A5060526986- Race, Genetics, and Society
- Epigenetics and DNA Methylation
- Psychoanalysis and Psychopathology Research
- Birth, Development, and Health
- Identity, Memory, and Therapy
- Ethics in Clinical Research
- SARS-CoV-2 and COVID-19 Research
- Child Abuse and Trauma
- Multisensory perception and integration
- Education, sociology, and vocational training
- Tactile and Sensory Interactions
- Child Welfare and Adoption
- Hearing Impairment and Communication
- Neuroethics, Human Enhancement, Biomedical Innovations
- Evaluation and Performance Assessment
- Prion Diseases and Protein Misfolding
- Mental Health and Psychiatry
- Health, Environment, Cognitive Aging
- Psychotherapy Techniques and Applications
- Hearing Loss and Rehabilitation
- Geographies of human-animal interactions
- Prenatal Substance Exposure Effects
- Empathy and Medical Education
- Social Representations and Identity
- BRCA gene mutations in cancer
Université Laval
2014-2024
Douglas Mental Health University Institute
2023
University of Exeter
2015
McGill University
2005-2012
Université Paris Cité
2008
Université de Montréal
2008
Transcatheter aortic valve implantation (TAVI) is a less invasive alternative to surgical replacement and the treatment of choice for patients at high operative risk. The role TAVI in lower risk unclear.To determine whether noninferior surgery moderately increased risk.In this randomized clinical trial conducted 34 UK centers, 913 aged 70 years or older with severe, symptomatic stenosis due age comorbidity were enrolled between April 2014 2018 followed up through 2019.TAVI using any CE mark...
Science & Society20 September 2017free access The biosocial genome? Interdisciplinary perspectives on environmental epigenetics, health and society Ruth Müller [email protected] Munich Center for Technology in Society (MCTS) School of Life Sciences Weihenstephan, Technical University Munich, Germany Search more papers by this author Clare Hanson Department English, Faculty Humanities, Southampton, UK Mark Institute Developmental NIHR Biomedical Research Centre, Southampton Hospital Michael...
Using the genetics of late onset Alzheimer's disease (LOAD) as illustrative, this paper argues for a reflexive critique involved science, specifically in connection with estimations increased risk. Following review social science commentary on genetic testing and screening general, current scientific understanding about molecular population LOAD is then presented. The results open-ended interviews conducted first-degree relatives individuals diagnosed at two study sites follow. It shown that...
In recent years, the evaluation of complex interventions has been great interest to members community. this special issue Canadian Journal Program Evaluation, we explore how evaluators, in their practice, approach interventions. The aim is not provide exhaustive coverage all different ways evaluating interventions, but rather inform practitioners on experiences seasoned evaluators.
This study explored why adult offspring of individuals with Alzheimer's disease (AD) sought genetic susceptibility testing for AD. Participants (N = 60) were a subset subjects from the first randomized controlled clinical trial to offer such testing. Qualitative analysis revealed two central constructs: altruism and learning. Planning future, hoping prevent AD, need know concepts that explained value These results add important contextual information into people might seek on their risk...
Abstract Throughout the process of being treated for mood and anxiety disorders, people dream "normal life" that awaits them. However, post-therapy, distinctiveness clinical normality (i.e., reduced symptomatology) social normativity become more apparent. In this article we suggest who have long felt socially excluded because their psychiatric symptoms, "normally shy" or awkward" is not enough. Instead they aspire to an ideal life. This confusion between means ends, a nonsymptomatic self,...
The aim of this special issue the Canadian Journal Program Evaluation was to present an overview current practices in field evaluation complex interventions. Seasoned evaluators described their approaches these types healthcare context. Building upon contributions, synthesis offers a cross-sectional reading experiences, highlighting common and divergent features as well most pressing concerns interests.
<ns4:p>In this Open Letter we bring together researchers from the Biosocial Birth Cohort Research (BBCR) network to reflect on interdisciplinary research and methods within birth cohorts draw attention social science approaches field, which argue are underutilized. A more comprehensive consistent integration of would expand scope value with cohorts. We critically engage three specific areas cohort that provide significant opportunities for exchange across disciplines; how exposure is defined...
In post-genomic science, the development of etiological models neurobiological vulnerability to psychiatric risk has expanded exponentially in recent decades, particularly since neuromolecular and biosocial turns basic research. Among this research is that McGill Group for Suicide Studies (MGSS) whose work centers on identification major factors epigenetic traits help identify a specific profile conditions (e.g., depression) predict high-risk behaviors suicidality). Although MGSS attracted...
Abstract When the artificial is natural: reconsidering what bionics and sensoria do. Videos of cochlear implant (CI) activation are common on online platforms such as YouTube, presenting a “magical” moment when people receive “the gift hearing.” We argue that these videos present distorted understanding bionic devices, specifically CIs, Our research focuses scientific understandings implants do within user's sensorium and, consequently, with CIs. The case CIs calls us to analyze subvert...
In this article, we explore a set of conceptual and technoscientific shifts that led to reconsiderations the experience hearing over twentieth twenty-first centuries, most specifically, through use cochlear implants (CIs). doing so, focus on factors are thought contribute CI users' experiences sound, including their potentially distinctive sensoria neural profiles, as they navigate spaces day-to-day lives both bearers objective audiograms subjective listeners. These increasingly broad,...
Deterministic dynamic models for coupled resident and invader populations are considered with the purpose of finding quantities that effective at predicting when invasive population will become established asymptotically. A key feature is stage-structure, meaning described by vectors discrete developmental stage- or age-classes. The vector structure permits exotic transient behaviour-phenomena not encountered in scalar models. Analysis using a linear Lyapunov function demonstrates class...
Argument In this article, we trace shifting narratives of trauma within psychiatric, neuroscience, and environmental epigenetics research. We argue that two contemporary – each which concerns questions time psychopathology, the past invading present had to be stabilized in order for models suicide risk posited. Through an examination these narratives, consider how early came understood as playing etiologically significant role development risk. Suicide, models, has come seen a behavior no...
Abstract Just over 20 years ago, molecular biologists Leonie Ringrose and Renato Paro published an article with a provocative title, “Remembering Silence”, in BioEssays. The focused on how epigenetic elements could return to their silent state, operationally defined as status before modulation by experimental or environmental factors. Though Paro's was fruit flies factors affecting embryological growth, the asked question of considerable importance rapidly expanding research neuroepigenetics...
Since 2013, we have studied the logic and narratives of an environmental epigenetics research team that studies correlations between early childhood adversity (ECA), specific biomarkers, suicide risk. Within this program, kin deceased participate in psychological autopsies, which researchers use to establish classify within a typology with or without abuse. We focus on words these family respondents their reflections life death loved ones, after death, consider slippery, transgressive,...