A5023199616- Reproductive Biology and Fertility
- Ovarian function and disorders
- Sperm and Testicular Function
- Chemotherapy-induced organ toxicity mitigation
- Reproductive Physiology in Livestock
- Ovarian cancer diagnosis and treatment
- Circadian rhythm and melatonin
- Renal and related cancers
- Endometriosis Research and Treatment
- Animal Genetics and Reproduction
- Seed Germination and Physiology
- Women's cancer prevention and management
- FOXO transcription factor regulation
- Sirtuins and Resveratrol in Medicine
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
- Ear Surgery and Otitis Media
- Maternal and Neonatal Healthcare
- Dietary Effects on Health
- Biochemical Acid Research Studies
- Otitis Media and Relapsing Polychondritis
- Phytochemical and Pharmacological Studies
- Genomics, phytochemicals, and oxidative stress
- Voice and Speech Disorders
- Digestive system and related health
Universidade Federal do Vale do São Francisco
2015-2024
Universidade Federal Rural de Pernambuco
2023-2024
Estácio (Brazil)
2024
Universidade do Vale do Sapucaí
2022
Universidade São Francisco
2015-2018
This study evaluated the receptor- and/or antioxidant stress-mediated mechanisms by which melatonin prevents ovarian toxicity of cisplatin treatment. The expression MT1 receptor in mouse ovaries was investigated immunohistochemistry. Pretreatment with (5, 10, or 20 mg/kg body weight, i.p.) before (5 administered to mice once daily for 3 days (phase I). pharmacological modulation via type 1 2 receptors analyzed administration antagonists (luzindole: nonselective MT1/MT2 antagonist; 5 weight...
We investigated the effects of insulin-like growth factor 1 (IGF-1) on morphology and follicular activation ovine preantral follicles cultured in situ whether phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway is involved IGF-1 action sheep ovary. Ovine ovarian fragments were fixed for histological terminal deoxynucleotidyl transferase dUTP nick-end labelling (TUNEL) analyses (fresh control) or supplemented alpha-minimum essential medium (α-MEM+; α-MEM+ with (1, 10, 50, 100...
The aim of this study was to evaluate the effects kaempferol on morphology, follicular activation, growth, and DNA fragmentation ovine preantral follicles cultured in situ, a phosphatidylinositol 3 kinase (PI3K) inhibitor expression phosphorylated protein B (pAKT) after culture. Ovine ovarian fragments were fixed for histological terminal deoxynucleotidyl transferase‐mediated dUTP nick‐end labeling (TUNEL) analyses (fresh control) or α‐MEM+ alone (control) with different concentrations (0.1,...
Esta revisão integrativa teve como objetivo identificar na literatura a produção científica que estabeleça uma relação entre vacinação contra o HPV e prevenção do câncer colo uterino. No período 24 de março 28 abril 2023, foi realizada busca bibliográfica seguindo os critérios inclusão: artigos publicados nos últimos cinco anos, em português, inglês ou espanhol Qualis CAPES mínimo B2. Para alcançar objetivos dessa revisão, foram selecionados partir da análise dos títulos, resumos leitura...
We aimed to study the effects of resveratrol on morphology, DNA fragmentation, follicular activation and cell proliferation after in vitro culture ovine ovarian tissue, verify if PI3K pathway is involved action sheep ovary. Ovaries were collected divided into fragments. One fragment was fixed for histology (fresh control). The remaining fragments cultured 7 days control medium (α-MEM+ ) alone or with (2, 10 30 µM). After culture, tissue destined morphological analysis. TUNEL proliferating...
Summary The present study aimed to investigate the effect of quercetin as an alternative antioxidant cysteamine on in vitro maturation. Oocytes were collected from goat ovaries, destined for maturation and distributed into three groups: CIS group, oocytes immersed MIV base medium; Groups Q4 Q8, medium adding 4 μM or 8 quercetin, respectively, cultured 24 h at 38.5°C with 5% CO 2 . groups presented same percentage expanded cumulus cells, but per cent Q8 group was significantly lower than that...
Abstract This study characterized the expression of melatonin receptor type 1 (MT ) protein in sheep ovaries, evaluated effects on primordial follicle survival and development after vitro culture ovarian tissue verified possible involvement phosphatidylinositol‐3‐kinase/protein kinase B/forkhead box O3a (PI3K/Akt/FOXO3a) pathway actions. Ovine fragments were cultured α‐modified minimum essential medium alone (α‐MEM + or supplemented with 100, 500, 1000 pg/ml for 7 days. PI3K inhibition was...
Summary The worldwide consumption of red wine, nuts and grapes has resulted in increased human exposure to resveratrol, which could affect reproductive function. However, the effect resveratrol on vitro culture early-stage ovarian follicles never been investigated. aims present study were evaluate sheep secondary follicle morphology, growth, DNA fragmentation, intracellular levels glutathione (GSH) active mitochondria. Secondary isolated from ovaries cultured for 18 days supplemented α -MEM...
The antioxidant properties of Amburana cearensis extract may be a useful substitute for standard cell culture medium. Thus, the aim this study was to evaluate effect extract, with or without supplementation, on in vitro survival and development sheep isolated secondary follicles. After collection ovaries, follicles were cultured 18 days α-MEM+ supplemented bovine serum albumin, insulin, transferrin, selenium, glutamine, hypoxanthine ascorbic acid (control medium) into medium composed...
This study evaluated the effects of kit ligand (KL) on morphology and development ovine preantral follicles (fresh control) after 7 days in vitro culture α-Minimal Essential Medium (α-MEM; control medium) or presence KL (1, 10, 50, 100 200 ng/ml). There was an increase percentage primary at concentration ng/ml KL, compared with fresh control, medium (α-MEM) other concentrations. Follicle diameter significantly higher than only concentrations 50 KL. In conclusion, promoted transition from...