A5040384843- Breast Cancer Treatment Studies
- Lymphoma Diagnosis and Treatment
- Cancer survivorship and care
- Breast Lesions and Carcinomas
- Advanced Breast Cancer Therapies
- Cancer Treatment and Pharmacology
- Breast Implant and Reconstruction
- Influenza Virus Research Studies
- Behavioral Health and Interventions
- Chronic Lymphocytic Leukemia Research
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Genomics and Diagnostics
- Physical Activity and Health
- Ovarian cancer diagnosis and treatment
- BRCA gene mutations in cancer
- Colorectal Cancer Treatments and Studies
- Economic and Financial Impacts of Cancer
- Cancer Risks and Factors
- Traumatic Brain Injury and Neurovascular Disturbances
- Viral-associated cancers and disorders
- Gastric Cancer Management and Outcomes
- Cancer-related cognitive impairment studies
- Global Cancer Incidence and Screening
- Neutropenia and Cancer Infections
- Reconstructive Surgery and Microvascular Techniques
Institut Bergonié
2015-2025
Swiss Cancer Center Léman
2024
École Polytechnique Fédérale de Lausanne
2024
École de Technologie Supérieure
2023
Sanofi (France)
2017-2023
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2023
Grenoble Institute of Neurosciences
2019
Inserm
2012-2019
Centre Hospitalier Universitaire de Grenoble
2019
Université de Bordeaux
2010-2019
Objective— Association between lipoprotein(a) (Lp(a)) level and a first-ever coronary (CHD) event is recognized. Less evident in patients with overt CHD stable symptoms whom we investigated associations Lp(a) future events. Approach Results— Relationships concentration cardiovascular disease outcomes during 6 years’ median follow-up were evaluated the Long-Term Intervention Pravastatin Ischaemic Disease (LIPID) study. concentrations measured plasma from 7863 who had sustained previous been...
This study aims to test the efficacy of text messaging cues ( SMS ) promote physical activity (PA) habit formation in workplace. Employees N = 49; 28 females and 21 males, M age 47.5 ± 8.29 years) were randomized into two parallel groups: a PA group enrolled 28‐week supervised program + same with received before their sessions. The exercise was assessed every week from self‐reports on an online application. maintenance several fitness measures also prior after intervention evaluate its...
PURPOSE Socioeconomic status (SES) influences the survival outcomes of patients with early breast cancer (EBC). However, limited research investigates social inequalities in their quality life (QoL). This study examines socioeconomic QoL after an EBC diagnosis and time trends. PATIENTS AND METHODS We used data from French prospective multicentric CANTO cohort (ClinicalTrials.gov identifier: NCT01993498 ), including women enrolled between 2012 2018. was assessed using European Organisation...
Triple-negative breast cancer (TNBC) patients have an increased risk of developing visceral metastases and other primary nonbreast cancers, particularly lung cancer. The differential diagnosis TNBC cancers from organs can be difficult due to lack a standard immunoprofile. We analyzed the diagnostic value estrogen receptor, progesterone human epidermal growth factor thyroid transcription factor-1 (TTF1), Napsin A, mammaglobin, gross cystic disease fluid protein 15 (GCDFP15), Sry-related...
Given the impact of individuals' habits on health, it is important to study how behaviors can become habitual. Cortisol has been well documented have a role in habit formation. This aimed elucidate influence circadian rhythm cortisol formation real-life setting.Forty-eight students were followed for 90 days during which they attempted adopt health behavior (psoas iliac stretch). They randomly assigned perform stretch either upon waking morning, when concentrations are high, or before evening...
Brentuximab vedotin was reported to be effective and safe against refractory/relapsed Hodgkin lymphoma in cohorts of between 12 102 patients. Herein we report our retrospective analysis the French experience with brentuximab used alone treat 240 patients enrolled a named patient program 2011 2013. All had histologically documented CD30+ lymphoma; 74% refractory disease or early relapses. After median 3 lines chemotherapy, infused intravenously (1.8 mg/kg every weeks). The primary endpoint...
Background This study assessed the prevalence and risk factors of unhealthy behaviors among survivors early‐stage breast cancer. Methods Women (n = 9556) from CANcer TOxicity cohort (NCT01993498) were included. Physical activity (PA), tobacco alcohol consumption, body mass index at diagnosis years 1 2 after diagnosis. A behavior was defined as if patients failed to meet PA recommendations (≥10 metabolic equivalent task hours per week), reduce/quit tobacco, or decrease consumption less than...
Importance As life span has increased among patients with cancer, survivorship become an important component of breast cancer care. Among concerns, adequate contraceptive counseling is needed for premenopausal who are not seeking to pregnant. Objective To examine use and chosen methods assess factors associated over time in early cancer. Design, Setting, Participants The Cancer Toxicity (CANTO) study was a multicenter nationwide prospective cohort that enrolled women diagnosed stage I III...
Abstract Background Many patients receiving adjuvant endocrine therapy (ET) for breast cancer experience side effects and reduced quality of life (QoL) discontinue ET. We sought to describe these issues develop a prediction model early discontinuation Methods Among with hormone receptor–positive HER2-negative stage I-III the Cancer Toxicities cohort (NCT01993498) who were prescribed ET between 2012 2017, upon stratification by menopausal status, we evaluated patterns including treatment...
E-scooters as a mode of transportation is rapidly growing in popularity. This study evaluates head impact conditions and injury risk associated with E-scooter crashes. A multibody model falls induced by wheel-curb collision was built compared an experimental crash test. total 162 scenarios were simulated to assess the effect fall (E-scooter initial speed inclination, obstacle orientation, user size) on kinematics. The forehead hit ground first 44% simulations. average tangential normal...
12051 Background: Worrisome thoughts are common future-oriented behaviors and may affect quality of life (QoL) years removed from BC diagnosis. We aimed to identify trajectories worry their determinants, focusing on age-related specificities. Methods: Disease-free stage I-III survivors CANTO (NCT01993498) completed the Impact Cancer scale v2 at end treatment (EoT) (Y) 1, 3, 5 post-EoT. Group-based were identified modeling continuous scores subscale (range: 1-5, higher = worse), which...
12036 Background: Fatigue, cognitive impairment, insomnia, anxiety, and depression are cancer-related behavioral symptoms that frequently co-occur share underlying risk factors. We investigated the clustering of these at different time points, aiming to identify drivers symptom segregation. Methods: Patients with stage I-III BC from CANTO (NCT01993498) were included. Hierarchical cluster analysis was performed three points: baseline (BC diagnosis), year (Y) 1 (3-6 months post-surgery,...
The aim of this study was to assess the efficacy neoadjuvant anastrozole and fulvestrant treatment large operable or locally advanced hormone-receptor-positive breast cancer not eligible for initial breast-conserving surgery, identify genomic changes occurring after treatment. One hundred twenty post-menopausal patients were randomised receive 1 mg (61 patients) 500 (59 6 months. Genomic DNA copy number profiles generated a subgroup 20 before A total 108 evaluable 118 toxicity. objective...
To perform a cartography of lymph node metastases in epithelial ovarian cancer and to determine predictive factors metastases.The charts 355 patients with who underwent lymphadenectomy during primary (n = 252) or secondary debulking surgery 103) were analyzed. The topography the was notified for whole group according stage disease, histological type, moment surgery. In before chemotherapy, independent prognostic variables risk involvement tested multivariate analysis. Independent combined...