A5035355129- Essential Oils and Antimicrobial Activity
- Helicobacter pylori-related gastroenterology studies
- Microbial Metabolites in Food Biotechnology
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Sesquiterpenes and Asteraceae Studies
- Phytochemicals and Antioxidant Activities
- Pediatric health and respiratory diseases
- Galectins and Cancer Biology
- Respiratory viral infections research
- Gut microbiota and health
- Tryptophan and brain disorders
- Pneumonia and Respiratory Infections
- Probiotics and Fermented Foods
- Meat and Animal Product Quality
- Phytochemistry and Bioactive Compounds
- Tea Polyphenols and Effects
- Diet and metabolism studies
- Seed and Plant Biochemistry
- Botany, Ecology, and Taxonomy Studies
- Phytochemical and Pharmacological Studies
- Diabetes and associated disorders
- Ethnobotanical and Medicinal Plants Studies
- Gastroesophageal reflux and treatments
- Influenza Virus Research Studies
Centro Científico Tecnológico - Córdoba
2025
Consejo Nacional de Investigaciones Científicas y Técnicas
2011-2022
Fundación Miguel Lillo
2020
University of Florida
2017
University of Münster
2013-2017
Instituto de Química del Noroeste Argentino
2014-2015
National University of Tucumán
2012-2015
Lactobacillus johnsonii N6.2 mitigates the onset of type 1 diabetes (T1D) in Biobreeding diabetes-prone rats, part, through changes kynurenine:tryptophan (K:T) ratios. The goal this pilot study was to determine safety, tolerance and general immunological response L. healthy subjects. A double-blind, randomized clinical trial 42 individuals with no known risk factors for T1D undertaken evaluate subject responses consumption N6.2. Participants received capsule/day containing 108 colony forming...
The American Academy of Pediatrics recommends that extremely preterm infants receive mother’s own milk (MOM) when available or pasteurized donor breast (DBM) MOM is unavailable. goal this study was to determine whether DBM could be inoculated with from mothers restore the live microbiota (RM). Culture dependent and culture independent methods were used analyze fluctuations in overall population microbiome, respectively, DBM, MOM, RM samples over time. Using at time=0 (T0) as target for...
The nasal priming with nonviable Lactobacillus rhamnosus CRL1505 (NV1505) or its purified peptidoglycan (PG1505) differentially modulates the respiratory innate immune response in infant mice, improving their resistance to primary syncytial virus (RSV) infection and secondary pneumococcal pneumonia. In association protection against RSV-pneumococcal superinfection, it was found that NV1505 PG1505 significantly enhance numbers of CD11c+SiglecF+ alveolar macrophages (AMs) producing interferon...
This work evaluated the ability of probiotic Streptococcus thermophilus CRL1190 strain and its exopolysaccharides to adhere gastric mucosa. Probiotic bacteria attachment human stomach epithelium was confirmed in tissue samples epithelial cell line AGS. In addition, it demonstrated that S. reduced Helicobacter pylori adhesion attenuated inflammatory response AGS cells. is first demonstration capacity mucosa, improve protection against H. through reduction modulation response. Therefore,...
The aim of this work is to study the oregano essential oil (OEO) composition from Northwestern Argentinean regions and evaluate its effect on lactic starter cultures. used, Origanum vulgare var hirtum, was obtained Andalgalá, Catamarca. presented high amounts α-terpinene (10%), γ-terpinene (15.1%), terpinen-4-ol (15.5%) thymol (13.0%) as main components. No negative growth or metabolic activity acid bacteria Streptococcus thermophilus CRL 728 813, Lactobacillus delbrueckii subsp. bulgaricus...
Lactobacillus fermentum UCO-979C (Lf979C) beneficially modulates the cytokine response of gastric epithelial cells and macrophages after Helicobacter pylori infection in vitro. Nevertheless, no vivo studies were performed with this strain to confirm its beneficial immunomodulatory effects. This work evaluated whether Lf979C improves protection against H. mice by modulating innate immune response. In addition, we exopolysaccharide (EPS) was involved significantly reduced TNF-α, IL-8, MCP-1...
Salimenaea integrifolia (Incayuyo) is a native aromatic and medicinal plant of Argentina, traditionally used for digestive ailments. This study assesses the morpho‐anatomical characteristics leaves, phenolic flavonoid content, essential oil composition, antioxidant activity aerial parts from 13 genotypes obtained through free pollination wild cultivated under controlled conditions. Morphological variations were observed in leaf size glandular trichome density. Essential analysis categorized...
Artemisia copa var. copa, popularly known as “copa”, “copa-copa”, “coa”, “copal” or “tola”, is an aromatic shrub that inhabits the high Andean peaks and Puna region of Chile, Bolivia, Argentina. Its aerial parts are sold in local markets a sedative, for treatment digestive disorders, hypertension, fever, urinary, respiratory infections, frictions to relieve rheumatism. The morpho-anatomy histochemistry native population A. (Catamarca province, Argentina) were described order determine...
The anti-inflammatory, antioxidant, antimicrobial and cytotoxic activities of the hexane (HE), chloroform (CE) methanol (ME) extracts obtained from bark Prunus tucumanensis Lillo were investigated. Both ME CE displayed a significant in vitro anti-inflammatory activity similar to dexamethasone commercial formulation (Pygeum) used for treatment benign prostatic hyperplasia (BPH). exhibited powerful antioxidant (67.6% relative BHT) free radical scavenging (RC50 = 5 ppm) activities, against...
Previously, we demonstrated that the non-viable strain Lacticaseibacillus rhamnosus CRL1505 (NV1505) or its purified peptidoglycan (PG1505) differentially modulated respiratory innate antiviral immune response triggered by Toll-like receptor (TLR)-3 activation in infant mice, improving resistance to primary syncytial virus (RSV) infection and secondary pneumococcal pneumonia. In this work, evaluated effect of other L. strains their peptidoglycans on impact infections. addition, duration...
The ability to form biofilms and the potential immunomodulatory properties of human gastric isolate Lactobacillus rhamnosus UCO-25A were characterized in vitro. It was demonstrated that L. is able on abiotic cell surfaces, modulate inflammatory response triggered by Helicobacter pylori infection epithelial cells THP-1 macrophages. exhibited a substantial anti-inflammatory effect both lines improved IL-10 levels produced challenged Additionally, protected AGS against H. with higher pathogen...
The intestinal environment may play a central role in the development of Type 1 Diabetes (T1D). However, use bacteria to alleviate onset this disease has been restricted studies rodent models. To date, ability Lactobacillus probiotic prevent T1D humans not evaluated. L. johnsonii N6.2 mitigated when administered Biobreeding diabetes‐prone rats by altering activity indoleamine 2,3‐dioxygenase‐1 (IDO), correlating with Th17 bias mesenteric lymph nodes animals protected from onset. Translating...