- Reproductive Biology and Fertility
- Prenatal Screening and Diagnostics
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Renal and related cancers
- COVID-19 Impact on Reproduction
- Ovarian function and disorders
University of Sadat City
2020-2022
King Abdulaziz Medical City
2022
Saad Specialist Hospital
2020
The prolonged lockdown of health facilities providing non-urgent gamete cryopreservation-as currently recommended by many reproductive medicine entities and regulatory authorities due to the SARS-CoV-2 pandemic will be detrimental for subgroups male infertility patients. We believe existing recommendations should promptly modified propose that same permissive approach sperm banking granted men with cancer is expanded other groups vulnerable These include patients (eg, azoospermic...
Abstract Purpose: To report the utilization of diagnostic intracytoplasmic sperm injection (D-ICSI), an ICSI cycle performed in natural cycle, to obtain information about embryo development potential after into zona pellucida (ZP)-free oocytes. Materials and Methods: We case a couple with primary unexplained infertility history previous failed, vitro fertilization (IVF-ICSI) cycles characterized by presence ZP-free Whole exome sequencing (WES) was carried out analyse possible genetic basis...
The aim of this study was to assess mitochondrial DNA analysis as a predictor the pregnancy potential biopsied preimplantation embryos. included 78 blastomeres from day 4 cleavage stage euploid embryo karyotype confirmed by 24-chromosome genetic testing for aneuploidies using Illumina Next-Generation Sequencing (NGS) system. Mitochondria viability ratios (mtV) were determined BAM files subjected web-based genome-analysis tool Galaxy. From cohort patients, 30.4% patients (n = 34) failed...
Abstract Study question Is mitochondrial DNA viability ratio of day–4 biopsied embryos associated with embryo implantation potential? Summary answer The is significantly higher in that implant. score might help to select euploid for single transfer. What known already Embryo euploidy a critical factor successful pregnancy outcomes. However, transfer does not invariably result implantation, thus indicating other factors may play role. Metabolic rates and adenosine triphosphate content vary...