Thomas K. Varghese

ORCID: 0000-0001-5867-6538
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Cardiac, Anesthesia and Surgical Outcomes
  • Radiomics and Machine Learning in Medical Imaging
  • Global Cancer Incidence and Screening
  • Diversity and Career in Medicine
  • Social Media in Health Education
  • Pleural and Pulmonary Diseases
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • COVID-19 and healthcare impacts
  • Gastric Cancer Management and Outcomes
  • Healthcare cost, quality, practices
  • Economic and Financial Impacts of Cancer
  • Cytomegalovirus and herpesvirus research
  • Health Literacy and Information Accessibility
  • Lung Cancer Research Studies
  • Healthcare Policy and Management
  • Cancer survivorship and care
  • Mathematics Education and Teaching Techniques
  • Patient-Provider Communication in Healthcare
  • Neuroendocrine Tumor Research Advances
  • Venous Thromboembolism Diagnosis and Management
  • Surgical Simulation and Training
  • Nutrition and Health in Aging

Huntsman Cancer Institute
2019-2025

University of Utah
2016-2025

University of Utah Health Care
2025

Northern Alberta Institute of Technology
2011-2024

Ananthapuri Hospitals and Research Institute
2024

Digital Scholar (United States)
2018-2023

English Heritage
2023

Charlottesville Medical Research
2023

New York Proton Center
2021-2023

University Hospitals of North Midlands NHS Trust
2023

The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations a multidisciplinary approach the management of patients with gastric cancer. For resectable locoregional cancer, guidelines recommend gastrectomy D1+ or modified D2 lymph node dissection (performed by experienced surgeons high-volume centers). Postoperative chemoradiation is preferred option after complete resection T3-T4 tumors node-positive T1-T2 tumors. chemotherapy...

10.6004/jnccn.2013.0070 article EN Journal of the National Comprehensive Cancer Network 2013-05-01

Esophageal cancer is the sixth most common cause of deaths worldwide. Adenocarcinoma more in North America and Western European countries, originating mostly lower third esophagus, which often involves esophagogastric junction (EGJ). Recent randomized trials have shown that addition preoperative chemoradiation or perioperative chemotherapy to surgery significantly improves survival patients with resectable cancer. Targeted therapies trastuzumab ramucirumab produced encouraging results...

10.6004/jnccn.2015.0028 article EN Journal of the National Comprehensive Cancer Network 2015-02-01

Overview Upper gastrointestinal tract cancers originating in the esophagus, esophagogastric junction (EGJ), and stomach constitute a major health problem around world. An estimated 37,640 new cases of 25,070 deaths from upper occurred United States 2010.1 A dramatic shift location tumors has States.2,3 Changes hisNCCN

10.6004/jnccn.2011.0072 article EN Journal of the National Comprehensive Cancer Network 2011-08-01

Nonsteroidal anti-inflammatory drugs (NSAIDs) have many physiologic effects and are being used more commonly to treat postoperative pain, but recent small studies suggested that NSAIDs may impair anastomotic healing in the gastrointestinal tract.

10.1001/jamasurg.2014.2239 article EN JAMA Surgery 2015-01-21

The extraordinary demands of managing the COVID-19 pandemic has disrupted world's ability to care for patients with thoracic malignancies. As a hospital's population increases and hospital resources are depleted, provide surgical is progressively restricted, forcing surgeons prioritize among their cancer populations. Representatives from multiple cancer, surgical, research organizations have come together guide triaging malignancies as impact evolves each hospital.

10.1016/j.athoracsur.2020.03.005 article EN other-oa The Annals of Thoracic Surgery 2020-04-09

The COVID-19 pandemic is an unprecedented global crisis. Surgical providers have been forced to reconsider almost every facet of their daily clinical practice. Elective surgeries are canceled, and clinics scaled back drastically irrespective healthcare system or geographic boundary. trainees stand side-by-side with all members the team confront ever-changing demands pandemic. Although full magnitude remains be seen in North America, we cannot ignore impact this new evolving "normal" state on...

10.1097/sla.0000000000003927 article EN Annals of Surgery 2020-04-16

BACKGROUND American Indians/Alaskan Natives (AI/ANs) have the worst 5‐year cancer survival of all racial/ethnic groups in United States. Causes for this disparity are unknown. The authors report examined receipt treatment among AI/AN patients compared with white patients. METHODS This was a retrospective cohort study 338,204 who were diagnosed at age ≥65 years breast, colon, lung, or prostate between 1996 and 2005 Surveillance, Epidemiology, End Results‐Medicare database. Nationally accepted...

10.1002/cncr.28683 article EN Cancer 2014-04-07

ABSTRACT Reactivation of cytomegalovirus (CMV) from latency is a frequent complication organ transplantation, and the molecular mechanism by which this occurs unknown. Previous studies have shown that allogeneic stimulation induces reactivation human CMV (HCMV) in vitro (64). We find transplantation vascularized kidneys murine (MCMV) HCMV immediate-early ( ie ) gene expression. This induction accompanied increased expression transcripts encoding inflammatory cytokines, including tumor...

10.1128/jvi.75.10.4814-4822.2001 article EN Journal of Virology 2001-05-15

BACKGROUND: Randomized controlled trials demonstrate the efficacy of arginine-enriched nutritional supplements (immunonutrition) in reducing complications after surgery. The effectiveness preoperative immunonutrition has not been evaluated a community setting. OBJECTIVE: This study aims to determine whether before elective colorectal surgery improves outcomes at large. DESIGN: is prospective cohort with propensity score–matched comparative evaluation. SETTINGS: was conducted Washington State...

10.1097/dcr.0000000000000740 article EN Diseases of the Colon & Rectum 2016-12-07
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