A5100765054- Advanced biosensing and bioanalysis techniques
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Chromatography in Natural Products
- Plant-based Medicinal Research
- Fluorine in Organic Chemistry
- Electrochemical sensors and biosensors
- Advanced Chemical Sensor Technologies
- Phytochemicals and Antioxidant Activities
- Toxic Organic Pollutants Impact
- Adsorption and biosorption for pollutant removal
- Phytochemistry and Biological Activities
- Water Quality Monitoring and Analysis
- Mass Spectrometry Techniques and Applications
- Natural product bioactivities and synthesis
- RNA Interference and Gene Delivery
- Carbon and Quantum Dots Applications
- Electrochemical Analysis and Applications
- DNA and Nucleic Acid Chemistry
- Traditional Chinese Medicine Analysis
- Plant tissue culture and regeneration
- Pesticide Residue Analysis and Safety
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Per- and polyfluoroalkyl substances research
Shenyang Pharmaceutical University
2022-2025
Tianjin University
2019-2025
Zhongda Hospital Southeast University
2023-2025
Brown University
2021-2025
Rhode Island Hospital
2020-2025
Sun Yat-sen University
2023-2025
The First Affiliated Hospital, Sun Yat-sen University
2025
Shaanxi Normal University
2015-2024
Northeastern University
2024
Shandong University of Traditional Chinese Medicine
2024
Advertising and feed ranking are essential to many Internet companies such as Facebook Sina Weibo. Among real-world advertising systems, click through rate (CTR) prediction plays a central role. There proposed models in this field logistic regression, tree based models, factorization machine deep learning CTR models. However, current works calculate the feature interactions simple way Hadamard product inner they care less about importance of features. In paper, new model named FiBiNET an...
The application of abundant and inexpensive fluorine feedstock sources to synthesize fluorinated compounds is an appealing yet underexplored strategy. Here, we report a photocatalytic radical hydrodifluoromethylation unactivated alkenes with industrial chemical, chlorodifluoromethane (ClCF2H, Freon-22). This protocol realized by merging tertiary amine-ligated boryl radical-induced halogen atom transfer (XAT) organophotoredox catalysis under blue light irradiation. A broad scope readily...
Abstract Immunotherapy with immune checkpoint inhibitors (CPIs) shows promising prospects for glioblastoma multiforme (GBM) but restricted results, mainly attributed to the immunosuppressive tumor microenvironment (TME) and limited antibody permeability of blood–tumor barrier (BTB) in GBM. Here, nanovesicles a macrophage‐mimicking membrane are described, that co‐deliver chemotactic CXC chemokine ligand 10 (CXCL10), pre‐activate microenvironment, anti‐programmed death 1 (aPD‐L1), interrupt...
Immunogenic cell death (ICD)-mediated immunization strategies have great potential against breast cancer. However, traditional neglect the increase in immunosuppressive metabolite, adenosine (ADO), during ICD, leading to insufficient therapeutic outcomes. In this study, it is found that A2A receptor (A2AR) significantly expressed cancer and positively associated with regulatory T (Treg) cells. Herein, a strategy combining Fe/Mo-based lipid peroxidation (LPO) nanoamplifiers A2AR blockade...
Background Alzheimer's disease (AD) is a complex neurodegenerative marked by increased amyloid-β (Aβ) deposition, tau hyperphosphorylation, impaired energy metabolism, and chronic ischemia-type injury. Cerebral microvascular dysfunction likely contributes to AD pathology, but its precise pathogenic role has been poorly defined. Objective To examine reactivity endothelium-dependent vasodilators small conductance calcium-activated potassium (SK) channel activity in an intracerebral...
Chemotherapy still accounts for a large proportion of the treatments tumors, but drug resistance and side effects caused by long-term chemotherapy should not be underestimated. In this work, combination strategy has been widely developed to overcome brought use single drugs improve therapeutic effect. However, in clinical applications, co-delivery is very difficult, different vivo kinetics due properties will lead decrease efficacy. Thus, design novel antitumor agents, including new platinum...
Abstract Background Pancreatic cancer (PC) is a highly lethal malignancy regarding digestive system, which the fourth leading factor of cancer-related mortalities in globe. Prognosis poor due to diagnosis at advanced disease stage, low rates surgical resection, and resistance traditional radiotherapy chemotherapy. In order develop novel therapeutic strategies, further elucidation molecular mechanisms underlying PC chemoresistance required. Ribosomal RNA biogenesis has been implicated...
The main aim of this study was to assess the free lipid composition plant community in a Chinese peatland. Twelve species from Dajiuhu Peatland were analyzed for compositions n-alkanes, n-fatty alcohols and sterols leaves roots. are significantly different between root leaf most plants. In some cases, roots yield more long chain n-alkanes n-alkanols than corresponding plant. half characterized by higher Cmax (homologue with maximum concentration) relative leaves. root-derived steroidal...