- Hair Growth and Disorders
- Reproductive tract infections research
- Healthcare Policy and Management
- Healthcare and Venom Research
- Global Health Workforce Issues
- Skin Protection and Aging
- Herpesvirus Infections and Treatments
- Cervical Cancer and HPV Research
- Liver Disease Diagnosis and Treatment
- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide Residue Analysis and Safety
- Pesticide and Herbicide Environmental Studies
- Diversity and Career in Medicine
- Traditional Chinese Medicine Studies
- Nutritional Studies and Diet
- Dermatology and Skin Diseases
- RNA modifications and cancer
- Ideological and Political Education
- Primary Care and Health Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Education and Work Dynamics
- Air Quality and Health Impacts
- Dermatologic Treatments and Research
- Liver Disease and Transplantation
- Biochemical effects in animals
Boston University
2022-2025
VA Boston Healthcare System
2022-2025
Beijing University of Chinese Medicine
2021-2025
Cleveland Clinic
2023-2025
Hainan University
2023-2024
Macau University of Science and Technology
2024
Shanghai East Hospital
2021-2024
Jilin Normal University
2024
Guangzhou Medical University
2024
Northeast Forestry University
2019-2024
The estimated glucose disposal rate (eGDR) has been linked to incident cardiovascular disease (CVD) in individuals without diabetes. However, few studies have accounted for long-term cumulative eGDR exposure. aim of this study was explore whether independently associated with CVD over the age 50 years and This used data from China Health Retirement Longitudinal Study (CHARLS) (HRS). calculated as summation average each pair consecutive examinations multiplied by time between these two...
The prevalence of depressive-like behavior is significantly higher in patients with cholestatic liver disease, leading to a notable reduction the quality life. This situation underscores urgent need investigate mechanisms underlying association between cholestasis and clinical depression. review provides comprehensive examination how neuroendocrine disorders resulting from influence onset depression through both direct indirect mechanisms. First, accumulation bile acids central nervous...
Pluripotent stem cells, including induced pluripotent and embryonic cells (ESCs), have less developed mitochondria than somatic and, therefore, rely more heavily on glycolysis for energy production.Citation1-3 However, how mitochondrial homeostasis matches the demands of nuclear reprogramming regulates pluripotency in ESCs is largely unknown. Here, we identified ATG3-dependent autophagy as an executor both remodeling during cell regulation ESCs. Dysfunctional by Atg3 deletion inhibited...
Introduction: With the rapid development of information technology and online communities, patients in growing numbers choose to consult physicians health communities (OHCs) for treatment. Although many researchers have examined OHCs, impact physicians' rating activeness on patient consultation choice, which is reflected by number has rarely been discussed. Methods: A computer program was developed download required data. We collected data from 8,401 an community, Good Doctor Online,...
Androgenic alopecia (AGA) is a highly prevalent form of non-scarring but lacks effective treatments. Stem cell exosomes have similar repair effects to stem cells, suffer from the drawbacks high cost and low yield yet. Cell-derived nanovesicles acquired through mechanical extrusion exhibit favorable biomimetic properties exosomes, enabling them efficiently encapsulate substantial quantities therapeutic proteins. In this study, we observed that JAM-A, an adhesion protein, resulted in...
Special attention has been paid to Hepatitis E (HE) prophylaxis for pregnant women due poor prognosis of HE in this population. We conducted a post-hoc analysis based on the randomized, double-blind, vaccine (Hecolin)-controlled phase 3 clinical trial human papillomavirus (HPV) (Cecolin) China. Eligible healthy aged 18-45 years were randomly assigned receive three doses Cecolin or Hecolin and followed up 66 months. All pregnancy-related events throughout study period closely up. The...
Abstract Background Paenibacillus polymyxa SC2, a bacterium isolated from the rhizosphere soil of pepper ( Capsicum annuum L.), promotes growth and biocontrol pepper. However, mechanisms interaction between P. SC2 have not yet been elucidated. This study aimed to investigate interactional relationship using transcriptomics. Results stems leaves in pot experiments greenhouse. Under conditions, peppers stimulate expression genes related quorum sensing, chemotaxis, biofilm formation SC2....
To assess the pattern of multiple human papillomavirus infection to predict type replacement postvaccination. A total 7372 women aged 18–45y from a phase III trial an Escherichia coli-produced HPV-16/18 vaccine were analyzed at enrollment visit before vaccination. Hierarchical multilevel logistic regression was used evaluate HPV and nonvaccine-type interactions with age as covariate. Binary construed compare infections single explore impact multiple-type on risk cervical disease. Multiple...
Acupuncture and related acupoint therapies have been widely used for smoking cessation. Some relevant systematic reviews (SRs) published. There is a need to summarize update the evidence inform practice decision-making.
Background Long-COVID (LC) refers to post-acute COVID-19 symptoms that can last for months or longer after the initial infection, affecting physical health of infected patients. This study aims investigate association between symptomology LC and mental patients in China. It also examine relationship perceived symptom burden these Methods A population-based stratified cluster sample was recruited, using a standard sampling procedure, from prefecture-level city Northern Participants included...
The application of pesticides in mixtures often exerts multiple pressures on agricultural soils the short term. Therefore, it is necessary to assess effects mixed environmental behavior and ecotoxicity soil. In this study, we assessed three common through soil degradation toxicity toward earthworm Eisenia fetida. Compared with half-lives (DT50) single pesticide, DT50 values avermectin, imidacloprid carbendazim binary were similar. However, their ternary approximately 1.5 times longer than...
Background: The Department of Veterans Affairs (VA) provides the largest Graduate Medical Education (GME) training platform for health professionals in United States. Studies on impact VA GME programs physician recruitment were lacking. Objectives: To examine size residency at a facility facility’s time-to-fill vacancies, and whether differs by socioeconomic deprivation public school quality geographic area. Project Design: We constructed an instrumental variable program interacting...
The assessment of human papillomavirus (HPV) genotype distribution in terms age and cervical lesions could contribute to the adoption more targeted preventive approaches specific populations against cancer. current study was conducted Ordos City, China, with aim analyzing HPV genotypes prevalence infection patterns within a hospital-based population.
Objectives To assess the therapeutic effects and safety of Tongxie Yaofang (TXYF) granules vs placebo as an alternative treatment for diarrhoea-predominant irritable bowel syndrome (IBS-D). We hypothesised that TXYF would improve clinical responses among patients with IBS-D. Design A randomised, double-blind, placebo-controlled, phase II, superiority trial. Setting Outpatients attending Fangshan Hospital, Beijing University Chinese Medicine, Beijing, China. Participants 96 eligible...
Abstract While ultraviolet radiation (UVR) exposure is a risk factor for skin cancer, there little evidence from prospective studies exploring the association with both malignant melanoma (MM) and in situ (MIS).1, 2 Within NIH-AARP Diet Health Study involving 491, 367 participants ages 50-71 when study began 1995, we investigated relationship between July erythemal UVR levels incidence of MM MIS prospectively. average noon-time ground-level dose measured July.3 were linked to participants’...
Most studies on adverse drug reactions (ADRs) of fluoroquinolones (FQs) have focused the mechanisms single ADRs, and no quantitative structure-activity relationship (QSAR) method been carried out that combine several ADRs FQs. In this study, an improved three-dimensional (3D) QSAR was established using fuzzy comprehensive evaluation. This could simultaneously consider three common FQs molecular parameters. The comprehensively predict provide direction for development new drugs with lower...