A5101526532- Kruppel-like factors research
- Plant-Microbe Interactions and Immunity
- Plant Parasitism and Resistance
- Plant Pathogenic Bacteria Studies
- Plant tissue culture and regeneration
- CRISPR and Genetic Engineering
- Power Systems and Technologies
- Plant Molecular Biology Research
- Transgenic Plants and Applications
- Advanced Computational Techniques and Applications
- Plant-based Medicinal Research
- Angiogenesis and VEGF in Cancer
- Developmental Biology and Gene Regulation
- Toxin Mechanisms and Immunotoxins
- Ubiquitin and proteasome pathways
- Biomedical and Engineering Education
- Antibiotics Pharmacokinetics and Efficacy
- Cancer, Hypoxia, and Metabolism
- Endoplasmic Reticulum Stress and Disease
- Cell Adhesion Molecules Research
- Phytochemistry and Biological Activities
- Plant Pathogens and Fungal Diseases
- Higher Education Learning Practices
- Cancer Cells and Metastasis
- Cancer-related gene regulation
State Key Laboratory of Hybrid Rice
2019-2024
Wuhan University
2008-2024
Fuzhou University
2021-2024
Nanchang University
2021-2024
China National Rice Research Institute
2019
Zhejiang University
2019
GlaxoSmithKline (United Kingdom)
2011
To explore how rice (Oryza sativa L.) can be safely produced in Cd-polluted soil, OsLCT1 and OsNramp5 mutant lines were generated by CRISPR/Cas9-mediated mutagenesis. One of (lct1×1) two mutants (nramp5×7 nramp5×9) evaluated for grain Cd accumulation agronomic performances. In paddy field soil containing approximately 0.9 mg/kg Cd, lct1×1 grains contained 40% (0.17 mg/kg) the concentration wild type parental line, less than China National Food Safety Standard (0.20 mg/kg). Both showed low (<...
The nucleotide-binding domain leucine-rich repeat (NLR) immune receptors play important roles in innate plant immunity. activation of NLRs is specifically induced by their cognate effectors released from pathogens. Autoactive are expected to confer broad-spectrum resistance because they do not need activate responses. In this study, we demonstrated that the NLR genes RPS2 and RPM1(D505V) Arabidopsis were autoactive Oryza sativa conferred fungal pathogen Magnaporthe oryzae, bacterial...
Nucleotide-binding site leucine-rich repeat receptors (NBS-LRR/NLRs) are crucial intracellular immune proteins in plants. Previous article reported a novel NLR protein SUT1 (SUPPRESSORS OF TOPP4-1, 1), which is involved autoimmunity initiated by type one phosphatase 4 mutation (topp4-1) Arabidopsis, however, its role planta still unclear. This study employed Nicotiana benthamiana, model platform, to conduct an overall structural and functional analysis of protein. The transient expression...
RPM1 is a plant immune receptor that specially recognizes pathogen-released effectors to activate effector-triggered immunity (ETI) in Arabidopsis thaliana. RPM1-mediated ETI results the hypersensitive response (HR) and disease resistance. Previous reports indicated Phospholipase D (PLD) positively regulated HR. However, single, double, triple pld knock-out mutants of 12 members PLD family A. thaliana did not show suppressed HR, indicating functional redundancy among members. In this study,...
Coding sequences (CDS) are commonly used for transient gene expression, in yeast two-hybrid screening, to verify protein interactions and prokaryotic expression studies. CDS most obtained using complementary DNA (cDNA) derived from messenger RNA (mRNA) extracted plant tissues generated by reverse transcription. However, some difficult acquire through this process as they expressed at extremely low levels or have specific spatial and/or temporal patterns vivo. These challenges require the...
The exocyst is a hetero-octameric complex that exhibits significant functional diversity in regulating biological processes and defense responses. In plants, the EXO70 proteins are important components of involved membrane trafficking, biotic abiotic interactions, as well cell wall formation. A previous study has indicated member EXO subfamily, EXO70E2, interacts with RIN4 to mediate plant immunity. this study, we found EXO70E2 RING-type E3 ligase Botrytis susceptible1 interactor (BOI),...
This paper studies the methods and strategies of network update land survey spatial data based on embedded terminal equipment server application multi-level distributed heterogeneous database.Web services model has been used to do design implementation work system update. The main procedure real-time method in this article includes: web asynchronous transmission, wireless transmission GPRS, updating, layer-grid index by applying setting many levels blocks,interactive operations between...
Phospholipase A2 (PLA2) is the key enzyme to venom from Deinagkistrodon acutus which one of highly venomous snakes in China. In addition being a catalyst for hydrolysis phospholipases snake venom, it's well known that it possesses broad spectrum pharmacological activities, such as myotoxicity, neurotoxicity, cardiotoxicity, and hemolytic, anticoagulant antiplatelet activities. However, snakebites are not efficiently treated by conventional serum therapy. Acute wounds can still cause...
<div>Abstract<p>Notch signaling is required for vascular development and tumor angiogenesis. Although inhibition of the Notch ligand Delta-like 4 can restrict growth disrupt neovasculature, effect inhibiting receptor function on angiogenesis has yet to be defined. In this study, we generated a soluble form Notch1 (Notch1 decoy) assessed its <i>in vitro</i> vivo</i>. decoy expression reduced stimulated by binding three distinct ligands inhibited morphogenesis...
Supplementary Figure 2 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 3 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 4 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 1 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 2 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 3 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis
Supplementary Figure 4 from A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis