A5088034678- Cardiac Imaging and Diagnostics
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Political and Economic history of UK and US
- Atrial Fibrillation Management and Outcomes
- Stroke Rehabilitation and Recovery
- Cardiovascular Function and Risk Factors
- Chemotherapy-induced cardiotoxicity and mitigation
- Vestibular and auditory disorders
- Vascular Malformations Diagnosis and Treatment
- Shoulder and Clavicle Injuries
- Cerebrovascular and Carotid Artery Diseases
- Renin-Angiotensin System Studies
- Pericarditis and Cardiac Tamponade
- Heart Failure Treatment and Management
- Neuroendocrine regulation and behavior
- Sarcoidosis and Beryllium Toxicity Research
- Cerebral Venous Sinus Thrombosis
- Metalloenzymes and iron-sulfur proteins
- Cerebrovascular and genetic disorders
- Spectroscopy Techniques in Biomedical and Chemical Research
- Anesthesia and Pain Management
- Trauma and Emergency Care Studies
- Neurological diseases and metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
NHS Greater Glasgow and Clyde
2025
University of Glasgow
2022-2024
Rotorua Hospital
2023
Royal Hobart Hospital
2016-2017
Beatson West of Scotland Cancer Centre
2017
Menzies School of Health Research
2016
National Neuroscience Institute
2016
University of Manchester
2014
University of St Andrews
2011
Wrightington Hospital
2010
An accurate prognostic model is extremely important in severe traumatic brain injury (TBI) for both patient management and research. Clinical prediction models must be validated internally externally before they are considered widely applicable. Our aim to independently validate two models, one developed by the Corticosteroid Randomization After Significant Head (CRASH) trial investigators, other from International Mission Prognosis Analysis of Trials Traumatic Brain Injury (IMPACT) group....
Standard Raman spectroscopy (SRS) is a noninvasive technique that used in the biomedical field to discriminate between normal and cancer cells. However, presence of strong fluorescence background detracts from use SRS real-time clinical applications. Recently, we have reported novel modulated (MRS) extract spectra background. In this paper, present first application MRS identification human urothelial cells (SV-HUC-1) bladder (MGH) urine samples. These results are compared those obtained by...
To compare characteristics between stroke populations with and without sensorineural hearing loss (SNHL) assess the impact of SNHL on outcome.
To investigate the uptake, safety and efficacy of docetaxel chemotherapy in hormone-naïve metastatic prostate cancer (mPC) first year use outside a clinical trial.Patients West Scotland Cancer Network with newly diagnosed mPC were identified from regional multidisciplinary team meetings their treatment details collected electronic patient records. The rate febrile neutropenia, hospitalisations, time to progression, overall survival compared between those patients who received...
Introduction: Traumatic brain injury (TBI) is a global concern associated with high mortality and morbidity. Costs to individuals society are extensive due poor recovery, long-term disability the young age group affected. Statins have emerged as potential therapeutic agents in TBI. This study aimed investigate protective effect of statins severe TBI.Methods: case-control included adults A sliding dichotomy approach was used dichotomize at 14-days Glasgow Outcome Score (GOS) 6 months....
Importance Typical cysteine-altering NOTCH3 ( cys ) variants are highly prevalent (approximately 1 in 300 individuals) and associated with a broad spectrum of small vessel disease (SVD), ranging from early-onset stroke dementia (cerebral autosomal dominant arteriopathy subcortical infarcts leukoencephalopathy [CADASIL]) to nonpenetrance. A staging system that captures the full -SVD severity is needed currently lacking. Objective To design simple clinicoradiological spectrum. Design, Setting,...
Background To assess the effectiveness of a peri-operative pain control regimen for day-case shoulder surgery, including open and complex procedures. Methods A prospective cohort study all patients undergoing surgery in single hospital over 1-year period, using comprehensive regimen. The included patient education, interscalene block, analgesics, nonsteroidal anti-inflammatory medications cold compression wrap. All were followed up with telephone call 24 hours after to their levels,...
The arcuate nucleus (ArcN) is an integrative hub for the regulation of energy balance, reproduction, and arterial pressure (AP), all which are influenced by Angiotensin II (AngII); however, cellular mechanisms downstream neurocircuitry unclear. Here we show that ArcN AngII increases AP in female rats via two phases, both mediated activation type 1 receptors (AT1aR): initial vasopressin-induced vasoconstriction, followed slowly developing sympathetic nerve activity (SNA) heart rate (HR). In...