A5029552690- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Urological Disorders and Treatments
- Genetics and Neurodevelopmental Disorders
- Genetic Syndromes and Imprinting
- Abdominal Surgery and Complications
- Genital Health and Disease
- Sperm and Testicular Function
- LGBTQ Health, Identity, and Policy
- Pneumothorax, Barotrauma, Emphysema
- Female Genital Mutilation/Cutting Issues
- Reproductive Health and Contraception
- Hernia repair and management
- Prenatal Screening and Diagnostics
Universidade Estadual de Campinas (UNICAMP)
2016-2022
Objective . To evaluate diagnosis, age of referral, karyotype, and sex rearing cases with disorders development (DSD) ambiguous genitalia. Methods Retrospective study during 23 years at outpatient clinic a referral center. Results There were 408 cases; 250 (61.3%) 46,XY 124 (30.4%) 46,XX 34 (8.3%) had chromosomes abnormalities. 189 (46.3%) testicular DSD, 105 (25.7%) ovarian 95 (23.3%) gonadal (DGD), 19 (4.7%) complex malformations. The main etiology DSD was salt-wasting 21-hydroxylase...
Abstract Background: Ovotesticular disorder of sex development (OT-DSD) (true hermaphroditism) is an anatomopathological diagnosis based on the findings testicular and ovarian tissues in same subject, gonad (ovotestis), or separate gonads. OT-DSD a rare cause ambiguity, most common karyotype 46,XX; mosaics chimeras are found only 10%–20%. Aim: To report case patient with constitution. Case report: A 2-month-old child male assignment was referred to our clinic for investigation ambiguity. He...
To evaluate, in a sample of patients with disorders sex development (DSD), data related to the age at referral and their correlation initial complaints, gender referral, defined after diagnosis etiological diagnosis.Retrospective review first consultation reason for it, social diagnosis, karyotype all cases treated DSD outpatient clinic between 1989 2016. Cases that did not involve diagnoses do usually ambiguous genitalia, thus requiring specialized monitoring, were excluded.Of 1793 cases,...
OBJETIVO: O pneumoperitônio produz várias alterações na fisiologia humana. Algumas destas alterações, como hipercapnia e acidose, dependem ou são agravadas com o uso de CO2, tendo maior repercussão em pacientes problema cardio-respiratório. A necessidade uma melhor alternativa para insuflação da cavidade; a observação que as cirurgias abertas, assim laparoscópicas suspensão mecânica, realizadas presença Ar ambiente; escassez trabalhos testando substituição ao CO2 cavidade, foram motivos...
BACKGROUND: Because normal male sexual differentiation is more complex than female differentiation, there are cases of disorders sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers rarely used in distinguishing such individuals. OBJECTIVES: To evaluate the function cells individuals genital ambiguity, karyotype, palpable gonads testosterone secretion. STUDY DESIGN AND SETTING: Case-control study 77 patients, including eight partial...
Objective: To describe the case of a male Prader-Willi syndrome (PWS) patient with atypical development features.
Inhibin B is a hormone produced by the Sertoli cells that can provide important information for investigation of disorders sex development (DSD) with 46,XY karyotype. The aim this study to compare two enzyme-linked immunosorbent assay (ELISA) assays dosage serum inhibin in patients DSD normal testosterone secretion.Twenty-nine and secretion (partial androgen insensitivity syndrome [PAIS] [n=8]; 5α-reductase deficiency [n=7] idiopathic [n=14]) were included. Molecular analysis AR SRD5A2 genes...
ou não de gônadas (3,40; p=0,18) e com o cariótipo (0,51; p=0,77).Conclusão: a definição do sexo criação antes da investigação etiológica nesta ampla casuística crianças abaixo um ano idade ambiguidade genital se relacionou à menor distância cidade nascimento moradia criança em relação Campinas (SP) maior gravidade genital.
To evaluate, in a sample of patients with disorders sex development (DSD), data related to the age at referral and their correlation initial complaints, gender referral, defined after diagnosis etiological diagnosis. Retrospective review first consultation reason for it, social diagnosis, karyotype all cases treated DSD outpatient clinic between 1989 2016. Cases that did not involve diagnoses do usually ambiguous genitalia, thus requiring specialized monitoring, were excluded. Of 1793 cases,...