A5000527783- Sexual Differentiation and Disorders
- Hormonal and reproductive studies
- HIV/AIDS Research and Interventions
- Folate and B Vitamins Research
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sex work and related issues
- Sexual function and dysfunction studies
- Adolescent Sexual and Reproductive Health
- Innovative Microfluidic and Catalytic Techniques Innovation
- Pharmacology and Obesity Treatment
- Radiopharmaceutical Chemistry and Applications
- Healthcare Regulation
- Growth Hormone and Insulin-like Growth Factors
- Testicular diseases and treatments
- Science and Education Research
- Sports Performance and Training
- Genital Health and Disease
- Metabolism and Genetic Disorders
- Adventure Sports and Sensation Seeking
- Hair Growth and Disorders
- Iron Metabolism and Disorders
- Cancer, Lipids, and Metabolism
- Physical Education and Gymnastics
Universidade Estadual de Campinas (UNICAMP)
2005-2022
Hospital de Clínicas da Unicamp
2005-2018
The effects of weight loss on erectile function and hormones have not been well studied. aim this study was to measure the degree which sexual in particular hormonal environment change after substantial loss, surgically non-surgically induced morbidly obese male a prospective randomized long-term controlled trial. Furthermore, how surgery makes difference when treating men envisaged context. We prospectively studied 20 for 24 months, divided into two groups: group A included 10 patients who...
Objective . To evaluate diagnosis, age of referral, karyotype, and sex rearing cases with disorders development (DSD) ambiguous genitalia. Methods Retrospective study during 23 years at outpatient clinic a referral center. Results There were 408 cases; 250 (61.3%) 46,XY 124 (30.4%) 46,XX 34 (8.3%) had chromosomes abnormalities. 189 (46.3%) testicular DSD, 105 (25.7%) ovarian 95 (23.3%) gonadal (DGD), 19 (4.7%) complex malformations. The main etiology DSD was salt-wasting 21-hydroxylase...
Testicular adrenal rest tumors (TART) can cause infertility in congenital hyperplasia (CAH) males.To determine TART prevalence patients with CAH due to 21-hydroxylase deficiency (21-OHD) and evaluate possible factors associated its development.This is a descriptive analytical cross-sectional study evaluating males the classical form of 21-OHD through testicular ultrasonography serum inhibin B dosages. Data on prescribed glucocorticoid dose levels 17- hydroxyprogesterone (17-OHP),...
The presence of neuroendocrine differentiation may play a key role in androgen-independent tumor progression. prognostic significance plasma chromogranin-A (CgA) was assessed series consecutive patients with high-risk prostate cancer (PCa).Twenty-three presenting PCa and 8 healthy individuals, as control group, had their blood samples collected to evaluate CgA, free total specific antigen, testosterone pilot study. correlations serum CgA levels PSA, testosterone, Gleason score, number foci...
Purpose The presence of neuroendocrine differentiation may play a key role in androgen-independent tumor progression. prognostic significance plasma chromogranin-A (CgA) was assessed series consecutive patients with high-risk prostate cancer (PCa). Patients and Methods Twenty-three presenting PCa 8 healthy individuals, as control group, had their blood samples collected to evaluate CgA, free total specific antigen, testosterone pilot study. correlations serum CgA levels PSA, testosterone,...
OBJECTIVE: To evaluate insulin resistance and lipid profile in women with congenital adrenal hyperplasia (CAH) caused by classical 21-hydroxylase deficiency (21OHD), their association body mass index (BMI) corticosteroid dosage. SUBJECTS AND METHODS: We assessed BMI, waist circumference, current glucocorticoid dosage, glucose, eighteen young (mean ± SD, 19.3 3.0 years) 21OHD CAH. RESULTS: BMI was normal 12 patients, 5 of them were overweight, 1 obese. Waist circumference high 7 patients....
OBJETIVO: Apresentar a experiência relativa pacientes com deficiência da enzima 5alfa-redutase tipo 2 provenientes de três serviços distintos no Brasil. CASUÍSTICA E MÉTODOS: Foram incluídos 25 sinais clínicos e hormonais pertencentes 23 famílias, 15 oriundas Bahia, 7 São Paulo 1 Minas Gerais. avaliados dados clínicos, moleculares. A análise molecular dos 5 éxons do gene SRD5A2 foi feita por meio técnica PCR, seguida seqüenciamento automático ou manual. RESULTADOS: Em 10 famílias havia...
Tumores malignos são a causa de milhões falecimentos no mundo todos os anos, porém detecção da doença em seu estágio inicial pode salvar vidas.Biomarcadores tumorais permitem diagnósticos mais precoces e menos invasivos, portanto vitais tratamento do câncer.Os nucleosídeos têm sido pesquisados
OBJETIVO: Avaliar as alterações de IGF-1, IGFBP-3, leptina e insulina após o uso doses reposição hormônio crescimento recombinante humano (rhGH) em crianças baixas pré-púberes com insuficiência renal crônica (IRC). CASUÍSTICA E MÉTODOS: Em 11 (3F:8M), idade média 9,6 anos, rhGH (0,23mg/Kg/semana) por 12 meses, foram dosados (antes, 6 meses início do tratamento rhGH) leptina, insulina, glicemia, IGF-1 IGFBP-3. RESULTADOS: As concentrações séricas glicemia não variaram significativamente no...
BACKGROUND: Because normal male sexual differentiation is more complex than female differentiation, there are cases of disorders sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers rarely used in distinguishing such individuals. OBJECTIVES: To evaluate the function cells individuals genital ambiguity, karyotype, palpable gonads testosterone secretion. STUDY DESIGN AND SETTING: Case-control study 77 patients, including eight partial...
You have accessJournal of UrologyInfertility: Therapy/Evaluation1 Apr 20101923 MORBID OBESE MEN PRESENT POOR SPERM QUALITY AND WHILE HORMONAL SEXUAL FUNCTIONS IMPROVE IT IS NOT REVERSED AFTER GASTRIC BYPASS – A LONG TERM FOLLOW UP Leonardo O. Reis, Ricardo D. Saade, Elintom A. Chaim, Laurione C. Oliveira, Adriano Fregonesi, and Ubirajara Ferreira ReisLeonardo Reis More articles by this author , SaadeRicardo Saade ChaimElintom Chaim OliveiraLaurione Oliveira FregonesiAdriano Fregonesi...
Inhibin B is a hormone produced by the Sertoli cells that can provide important information for investigation of disorders sex development (DSD) with 46,XY karyotype. The aim this study to compare two enzyme-linked immunosorbent assay (ELISA) assays dosage serum inhibin in patients DSD normal testosterone secretion.Twenty-nine and secretion (partial androgen insensitivity syndrome [PAIS] [n=8]; 5α-reductase deficiency [n=7] idiopathic [n=14]) were included. Molecular analysis AR SRD5A2 genes...
O projeto teve como objetivo avaliar o impacto da doenca Diabetes mellitus tipo 1 em adolescente na visao dos responsaveis. A relevância do estudo justifica-se pela necessidade de subsidiar a assistencia enfermagem, no que se refere as orientacoes prestadas bem ao atendimento e acompanhamento desses adolescentes visando minimizar gerado pelo suas complicacoes. metodologia utilizada constituiu-se com abordagem qualitativa carater descritivo. campo utilizado para realizacao pesquisa foi...
O estudo teve a finalidade de estudar o efeito da hiperhomocisteinemia (HHcy) leve no desenvolvimento aterosclerose, usando camundongos deficientes apolipoproteina E (apoE-/-) e receptor LDL (LDLR-/-). As concentracoes homocisteina (Hcy) plasmatica foram analisadas por HPLC-MS/MS. Foi realizada analise histologica das lesoes ateroscleroticas do seio aortico. lipidicas quantificadas programa Image Pro Plus software (versao 3.0). objetivo deste foi analisar dos receptores A estatistica...
A partir do tecido da prostata e liquido seminal pode-se obter o Antigeno Prostatico Especifico (PSA), que uma glicoproteina secretada pela prostata. O PSA desempenha a funcao de serina proteinase, sua atividade proteolitica inibida formacao irreversivel complexos com inibidores protease, alfa-1-antiquimotripsina alfa-2-macroglobulina, alem outras proteinas fase aguda. Habitualmente, concentracoes elevadas no soro sao indicadores doencas prostata, presenca fluido cervicovaginal impositiva...