- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Body Contouring and Surgery
- Pancreatitis Pathology and Treatment
- Cardiovascular Disease and Adiposity
- Pancreatic and Hepatic Oncology Research
- Obesity and Health Practices
- Diet, Metabolism, and Disease
- Gastrointestinal disorders and treatments
- Nutrition and Health in Aging
- Healthcare Regulation
- Gallbladder and Bile Duct Disorders
- Adipose Tissue and Metabolism
- Eating Disorders and Behaviors
- Gastric Cancer Management and Outcomes
- Liver Disease and Transplantation
- Esophageal and GI Pathology
- Health and Lifestyle Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Youth, Drugs, and Violence
- Pediatric Hepatobiliary Diseases and Treatments
- Obesity, Physical Activity, Diet
Universidade Estadual de Campinas (UNICAMP)
2016-2025
Hospital de Clínicas da Unicamp
2008-2023
Centro Universitário da Cidade
2016-2020
Altera (United States)
2012
Institute of Surgery named after A. V. Vishnevskogo
1993
Universidade de São Paulo
1993
Hôpital Purpan
1993
Universitat de Barcelona
1993
Hammersmith Hospital
1993
The effects of weight loss on erectile function and hormones have not been well studied. aim this study was to measure the degree which sexual in particular hormonal environment change after substantial loss, surgically non-surgically induced morbidly obese male a prospective randomized long-term controlled trial. Furthermore, how surgery makes difference when treating men envisaged context. We prospectively studied 20 for 24 months, divided into two groups: group A included 10 patients who...
OBJECTIVE Inflammation and dysfunction of the hypothalamus are common features experimental obesity. However, it is unknown whether obesity massive loss body mass can modify immunologic status or functional activity human brain. Therefore, aim this study was to determine effect reduction on brain functionality. RESEARCH DESIGN AND METHODS In humans, changes in hypothalamic after a meal glucose intake be detected by magnetic resonance imaging (fMRI). Distinct fMRI analytic methods have been...
Abstract Visceral adiposity is a risk factor for severe COVID-19, and link between adipose tissue infection disease progression has been proposed. Here we demonstrate that SARS-CoV-2 infects human undergoes productive in fat cells. However, susceptibility to the cellular response depends on anatomical origin of cells viral lineage. express more ACE2 are susceptible than their subcutaneous counterparts. leads inhibition lipolysis cells, while visceral it results higher expression...
Insulin resistance ameliorates after bariatric surgery, yet there is still a need for data on the acute effect of Roux-en-Y gastric bypass (RYGBP) insulin sensitivity.The objective study was to describe RYGBP sensitivity, measured by both euglycemic-hyperinsulinemic clamp and homeostasis model assessment index (HOMA-IR).Evaluations were conducted before 1 month at State University Campinas (São Paulo, Brazil).Patients included 19 premenopausal women with metabolic syndrome aged 35.3 (6.7)...
The effect of weight loss (WL) on histopathological aspects non-alcoholic fatty liver disease (NAFLD) may provide further insights into the dynamics hepatic recovery after WL.To analyze effects pre-operative WL insulin resistance- and NAFLD-related histology in individuals undergoing bariatric surgery (BS) with or without WL.A matched cross-sectional study was conducted at a public university hospital private clinic Campinas, Brazil.An analytical, observational, using prospectively collected...
The visceral fat is linked to insulin resistance, the metabolic syndrome, type 2 diabetes and an increased cardiovascular risk, but it not clear whether has a causative role.Surgical resection of this depot research model address issue. Twenty premenopausal women with syndrome grade III obesity were randomized undergo Roux-en-Y gastric bypass (RYGBP) either alone or combined omentectomy. Insulin sensitivity (IS; euglycemic-hyperinsulinemic clamp), acute response glucose (AIR; intravenous...
ABSTRACT Background Non-invasive markers are useful and practical tools for assessing non-alcoholic fatty liver disease (NAFLD), but biopsy remains the gold-standard method. Liver can be easily obtained on individuals undergoing bariatric surgery, there is no ultimate evidence relationship between costs, risks benefits of its systematic performance. Objective To compare diagnostic accuracy non-invasive methods with detection staging NAFLD in obese surgery. Methods This a cross-sectional,...
In Brief Objective: To compare duodenal-jejunal bypass (DJB) with standard medical care in nonobese patients type 2 diabetes and evaluate surgically induced endocrine metabolic changes. Methods: Eighteen submitted to a DJB procedure met the following criteria: overweight, diagnosis less than 15 years, current insulin treatment, residual β-cell function, absence of autoimmunity. Patients who refused surgical treatment received (control group). At baseline, 3, 6, 12 months after surgery,...
- Bariatric surgery has become the gold standard treatment for morbid obesity, but access to remains difficult and low compliance postoperative follow-up is common. To improve outcomes, enable optimize follow-up, we developed a multidisciplinary preoperative approach bariatric surgery.- determine impact of this program in outcomes Brazilian public health system.- A prospective evaluation individuals who underwent comparison their surgical with those observed prospectively collected...