A5017427059- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Sports Performance and Training
- Genomics and Phylogenetic Studies
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Antioxidant Activity and Oxidative Stress
- Agricultural and Food Sciences
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Microbial Community Ecology and Physiology
- Genetics and Physical Performance
- Diet, Metabolism, and Disease
- Heat shock proteins research
- Enzyme Production and Characterization
- Plant tissue culture and regeneration
- Plant Pathogenic Bacteria Studies
- Immune Cell Function and Interaction
- Eating Disorders and Behaviors
- Liver Disease Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Phytochemicals and Antioxidant Activities
- Cardiovascular Disease and Adiposity
- Toxin Mechanisms and Immunotoxins
Universidade de São Paulo
2012-2019
Universidad San Pedro
2017
Fundação de Amparo à Pesquisa do Estado de São Paulo
2017
Universidade Federal do Paraná
2005-2013
Orange juice is considered an excellent dietary source of several bioactive compounds with beneficial properties for human health. Citrus sinensis Osbeck cv. 'Cara Cara' a bud mutation originated from 'Washington' navel orange, also known as 'Bahia' orange. The ascorbic acid, flavonoid, and carotenoid contents in pasteurized nonpasteurized Bahia Cara juices using two LC-MS/MS platforms were investigated. Higher acid content was observed compared to both juices. Total flavanones well...
Sarcopenia describes an age-related decline in skeletal muscle mass, strength, and function that ultimately impairs metabolism leads to poor balance, frequent falling, limited mobility, a reduction quality of life. Here we investigate the pathogenesis sarcopenia through proteomic shotgun approach. In brief, employed tandem mass tags quantitate compare protein profiles obtained from young versus old rat slow-twitch type (soleus) fast-twitch (extensor digitorum longus, EDL). Our results...
Oxidative stress and inflammation play a role in the physiopathology of insulin resistance, diabetes cardiovascular disease. A single high-fat, high-carbohydrate (HFHC) meal induces an increase inflammatory oxidative markers peripheral blood mononuclear cells (PBMC). Previous studies have shown that orange juice is able to prevent this response by inhibiting toll like receptors (TLR) expression endotoxemia. Our goal was study proteome PBMC after consumption HFHC consumed with water, or...
AbstractAbstractThe participation of thiol-oxidoreductases such as thioredoxin during implantation, embryogenesis and fetal development has been extensively studied. Here, we analyzed the expression superfamily enzyme quiescin Q6/sulfhydryl oxidase (QSOX) development. Results show that QSOX is present in bovine serum (4 months' gestation), but its levels decrease with time after birth (from P1 to P60). We also demonstrate a sulfhydryl activity correlates sera, suggesting putative role redox...
This study aimed to develop an equipment and system of resistance exercise (RE), based on squat-type for rodents, with control training variables. We developed operant conditioning composed sound, light feeding devices that allowed optimized RE performance by the animal. With this system, it is not necessary impose fasting or electric shock animal perform task proposed (muscle contraction). Furthermore, possible muscle function tests in vivo within context variables such as intensity, volume...
Abstract Herbaspirillum seropedicae is an endophytic diazotroph associated with economically important crops such as rice, sugarcane, and wheat. Here, we present a 2‐D reference map for H. . Using MALDI‐TOF‐MS identified 205 spots representing 173 different proteins calculated average of 1.18 proteins/gene. Seventeen hypothetical or conserved ORFs were shown to code true gene products. These data will support the genome annotation process provide basis on which undertake comparative...
Branched-chain amino acids (BCAA) (especially leucine) have been shown to activate protein synthesis pathways, decrease proteolysis and increase insulin sensitivity. Furthermore, it appears that leucine can be used as a nutritional therapy avoid sarcopenia skeletal muscle atrophy due immobilization or glucocorticoid treatment. However, is of note all these conditions are related resistance varying degrees affect different tissues, particularly muscle. Additionally, evidence from recent...
Chronic inflammation contributes to the pathophysiology of many chronic diseases. Dietary fibers and antioxidants may exert anti-inflammatory effects. The objective this study was determine whether meals with different elicit a response in inflammatory markers healthy volunteers. On 3 separate days, subjects (n = 8) consumed one three isocaloric antioxidant (vitamin E, selenium β-carotene) fiber content (high, intermediate low) randomized crossover design. Blood samples were collected at...
An overconsumption of refined added sugars may cause inflammation, insulin resistance and an increase in visceral adiposity. It is important to highlight that sugar devoid micronutrients phytochemicals natural sweeteners such as malt extract honey have a different effect oxidative stress markers overall health. Malt contains approximately 90% carbohydrate, most it the form maltose, B vitamins (mainly niacin), amino acids some minerals magnesium potassium. also rich phenolic compounds mainly...
Coffee is one of the most valuable agricultural commodities.There much agronomic research on coffee, but molecular knowledge its fruit development and ripening limited.This study reports a comparative proteomic investigation immature coffee fruits in two early developmental stages: stage 1, cell division elongation perisperm; 2, growth endosperm progressively replacing perisperm.Proteins were extracted using modified SDSphenol method two-dimensional electrophoresis gels stained with...
PURPOSE: The objective of this study was to carry out a comparative phosphoproteome analysis soleus and EDL muscles young (6 months) old rats (22 supplemented with low dose high leucine. METHODS: Food-deprived (18h) (both groups) were assigned randomly one three treatments: control (saline), leucine (0.135g/kg) or (1.35g/kg) by oral gavage. Thirty min after the administration amino acid, killed decapitation collected stored at -80°C. proteins extracted in lysis buffer using cell disruptor...
mudanças no comportamento alimentar, que estão associados com o desejo de comer alimentos altamente palatáveis. Embora não haja uma relação causal clara, existe associação entre excessivo chocolate e as hormonais do ciclo menstrual. Examinamos efeito dos consumos leite maior teor cacau (50%) adicionado fibras por doces sintomas síndrome tensão pré-menstrual em 19 participantes. Este estudo experimental aberto durou 2 ciclos menstruais, incluindo fase controle (fase I) ingestão (50 g/dia)...