Priscilla P. Barbosa
A5044581219- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- Malaria Research and Control
- Viral Infections and Vectors
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- Insect symbiosis and bacterial influences
- Infection Control and Ventilation
- COVID-19 and Mental Health
- Biosensors and Analytical Detection
- Poxvirus research and outbreaks
- Virus-based gene therapy research
- Medical Device Sterilization and Disinfection
- Dengue and Mosquito Control Research
- Virology and Viral Diseases
- Cardiovascular Health and Disease Prevention
- Wildlife Ecology and Conservation
- Vibrio bacteria research studies
- Vaccine Coverage and Hesitancy
- Meta-analysis and systematic reviews
- Non-Invasive Vital Sign Monitoring
- Cardiovascular Disease and Adiposity
- Bacterial Identification and Susceptibility Testing
- Wildlife-Road Interactions and Conservation
Universidade Estadual de Campinas (UNICAMP)
2021-2025
Cardiff University
2025
Universidade Federal de Jataí
2024
Imperial College London
2021
Universidade Federal de Roraima
2021
University of Oxford
2021
Universidade Feevale
2021
Universidade de São Paulo
2021
Fundação Oswaldo Cruz
2016-2017
Universidade Federal de São Paulo
2011
Zika virus (ZIKV) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. The primarily transmitted by mosquito bite, although routes infection have implicated in some cases. Aedes aegypti considered to be the main vector humans worldwide; however, there evidence species, including Culex quinquefasciatus, transmit virus. To test potential Cx. quinquefasciatus ZIKV, we experimentally compared competence...
Mutations accrued by SARS-CoV-2 lineage P.1-first detected in Brazil early January, 2021-include amino acid changes the receptor-binding domain of viral spike protein that also are reported other variants concern, including B.1.1.7 and B.1.351. We aimed to investigate whether isolates wild-type P.1 can escape from neutralising antibodies generated a polyclonal immune response.We did an immunological study assess effects on B SARS-CoV-2, using plasma samples patients previously infected with...
BackgroundChikungunya virus (CHIKV) is an Aedes mosquito-borne that has caused large epidemics linked to acute, chronic, and severe clinical outcomes. Currently, Brazil the highest number of chikungunya cases in Americas. We aimed investigate spatiotemporal dynamics recurrence pattern since its introduction 2013.MethodsIn this epidemiological study, we used CHIKV genomic sequencing data, vector information, aggregate data on from Brazil. The comprised 241 Brazilian genome sequences GenBank...
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes acute, subacute, and chronic human arthritogenic diseases and, in rare instances, can lead to neurological complications death. Here, we combined epidemiological, virological, histopathological, cytokine, molecular dynamics, metabolomic, proteomic, genomic analyses investigate viral host factors contribute chikungunya-associated (CHIK) Our results indicate CHIK deaths are associated with multi-organ infection, central...
Abstract Visceral adiposity is a risk factor for severe COVID-19, and link between adipose tissue infection disease progression has been proposed. Here we demonstrate that SARS-CoV-2 infects human undergoes productive in fat cells. However, susceptibility to the cellular response depends on anatomical origin of cells viral lineage. express more ACE2 are susceptible than their subcutaneous counterparts. leads inhibition lipolysis cells, while visceral it results higher expression...
Background: A new SARS-CoV-2 lineage, named P.1 (20J/501Y.V3), has recently been detected in Brazil. Mutations accrued by the lineage include amino acid changes receptor-binding domain of spike protein that also are reported variants concern United Kingdom (B.1.1.7) and South Africa (B.1.325).Methods: We isolated two P.1-containing specimens from nasopharyngeal bronchoalveolar lavage samples patients Manaus, measured neutralization virus after incubation with plasma 19 COVID-19 convalescent...
Monkeypox virus (MPXV) infection was classified as a public health emergency of international concern by the World Health Organization (WHO) in 2022, being transmitted between humans large respiratory droplets, contact with skin lesions, fomites, and sexually. Currently, there are no available accessible simple-to-use diagnostic tests that accurately detect MPXV antigens for decentralized frequent testing. Here, we report an electrochemical biosensor to saliva plasma samples within 15 min...
We documented 4 cases of severe acute respiratory syndrome coronavirus 2 reinfection by non-variant concern strains among healthcare workers in Campinas, Brazil. isolated infectious particles from nasopharyngeal secretions during both infection episodes. Improved and continued protection measures are necessary to mitigate the risk for workers.
Abstract Zika virus (ZIKV) is a flavivirus that has recently been associated with increased incidence of neonatal microcephaly and other neurological disorders. The primarily transmitted by mosquito bite, although routes infection have implicated in some cases. Aedes aegypti considered to be the main vector humans worldwide, but there evidence species, including Culex quinquefasciatus , playing role Brazilian outbreak. To test this hypothesis, we experimentally compared vectorial competence...
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is mainly transmitted by airborne droplets generated infected individuals. Since this and many other pathogens are able to remain viable on inert surfaces for extended periods of time, contaminated play an important role in SARS-CoV-2 fomite transmission. Cosmetic products destined be applied infection-sensitive sites, such as the lips eyelids. Therefore, special biosafety precautions should incorporated into routine procedures...
Aedes aegypti (L.) has become an efficient vector of important arboviruses due to its anthropophilic and domiciliary behaviors. Since the 1980s, dengue affects thousands people every year in Brazil; Fernando de Noronha (FN), a touristic archipelago, cases have occurred since 2001. Once Ae. populations are well established inhabited areas FN, threat or another arbovirus epidemic is continuously imminent. This study aimed monitor DENV serotypes mosquito samples collected where at least one...
The main goal of this dataset is a compilation geo-referenced road-kill data from published and unpublished road surveys. encompasses records 45 personal communications 26 studies in peer-reviewed journals, theses, reports. comprises 21,512 records, 83% which are identified to the species level (n = 450 species). This can be used identify taxa seem vulnerable traffic, analyze temporal spatial patterns at local, regional, national scales also understand effects on population persistence....
Numerous studies have focused on inflammation-related markers to understand COVID-19. In this study, we performed a comparative analysis of spike (S) and nucleocapsid (N) protein-specific IgA, total IgG subclass response in COVID-19 patients compared their disease outcome. We observed that the SARS-CoV-2 infection elicits robust IgA against N-terminal (N1) C-terminal (N3) region N protein, whereas failed detect antibodies weak disordered linker (N2) patients. S IgG1, IgG2 IgG3 was...
A SARS-CoV-2 B.1.1.7 variant of concern (VOC) has been associated with increased transmissibility, hospitalization, and mortality. This study aimed to explore the factors VOC infection in context vaccination. On March 2021, we detected RNA nasopharyngeal samples from 14 22 individuals vaccinated a single-dose ChAdOx1 (outbreak A, n = 26), 42 two doses CoronaVac vaccine B, 52) for breakthrough rates 63.6% 52.4% CoronaVac. The outbreaks were caused by independent clusters VOC. serum...
O vírus da dengue é transmitido pelo mosquito Aedes aegypti infectado. É uma das arboviroses mais presentes no mundo. Nota-se um aumento do número de casos Brasil nos últimos anos, chegando há 4 milhões prováveis notificados apenas até o período abril 2024. As manifestações clínicas vão desde forma assintomática, formas leves complicações graves como choque e alterações neurológicas morte. objetivo trabalho analisar as possíveis sistema nervoso central. Trata-se revisão narrativa dos 5 anos...
Background: Although poliomyelitis caused by wild-type poliovirus has been almost eradicated, especially in developed countries, vaccine associated paralytic (VAPP) cases still continue to occur Latin American countries. In Argentina, where OPV routine immunization policy is ongoing, the last wild (WPV) case was registered 1984. Since then, several polio reported were VAPP and Vaccine Derived Poliovirus (VDPV) (first iVDPV detected 1998). Methods: To report a VDPV an immunodeficient patient...
Characterize the pulse wave velocity (PWV) of patients seen at outpatient clinic a medical school in Brazil.102 were analyzed and underwent central pressure assessment using Mobil O''Graph device.Among 102 analyzed, 63 (61.7%) female mean age was 58.7 years (+-13.2) body mass index 23.6 (+-17.2). Peripheral systolic had 144.7mmHg (+-23.9) peripheral diastolic 89.9mmHg (+-14.4). The 148.7mmHg (+-26.7) 92.3 mmHg (+-15.0). an average 7.0 m/s (+-3.1). PWV is gold standard test for assessing...
Abstract Chikungunya virus (CHIKV) is an Aedes mosquito-borne that has caused explosive epidemics linked to acute, chronic, and severe clinical outcomes. Since 2014, Brazil had the highest number of chikungunya fever (CHIKF) cases in Americas. Here, we report contextualize spatiotemporal dynamic CHIKF combine genomic, epidemiological, vector analyses investigate recurrence several Brazilian states. From 2013 2022, CHIKV seven epidemic waves across Brazil, affecting 59.5% (3,316 5,570)...
Background: Some studies have determined that the SARS-CoV-2 B.1.1.7 variant of concern (VOC) has been associated with increased transmissibility, hospitalization, and mortality. This study aimed to explore factors VOC infection in context vaccination adenovirus-vectored inactivated vaccines.Methods: We analyzed epidemiological, clinical, laboratory data from simultaneous COVID-19 outbreaks a convent (Outbreak A) long-term care facility B) individuals vaccinated single dose ChAdOx1 or two...