- Design Education and Practice
- Creativity in Education and Neuroscience
- Cardiovascular Function and Risk Factors
- Cognitive Science and Mapping
- Environmental Education and Sustainability
- Noise Effects and Management
- Sustainable Building Design and Assessment
- Neuroscience, Education and Cognitive Function
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Complex Systems and Decision Making
- Cardiovascular Effects of Exercise
- Urban Green Space and Health
- Cardiovascular Disease and Adiposity
- Quality and Safety in Healthcare
- Optical Imaging and Spectroscopy Techniques
- Multiple Sclerosis Research Studies
- Technology Assessment and Management
- Cardiomyopathy and Myosin Studies
- Atrial Fibrillation Management and Outcomes
- Genetic Neurodegenerative Diseases
- Product Development and Customization
- Biomedical and Engineering Education
- EEG and Brain-Computer Interfaces
Northwestern University
2020-2024
Cardiovascular Institute of the South
2024
Texas A&M University
2024
Swansea Bay University Health Board
2022-2024
Swansea University
2024
Virginia Tech
2018-2023
University of California, Berkeley
2020-2023
Cardiff University
2012-2022
University of North Carolina at Charlotte
2020-2022
Institut National des Sciences Appliquées de Lyon
2020
Transthyretin amyloid cardiomyopathy, an often unrecognized cause of heart failure, is now treatable with a transthyretin stabilizer. It therefore important to identify at-risk patients who can undergo targeted testing for earlier diagnosis and treatment, prior the development irreversible failure. Here we show that random forest machine learning model potential wild-type cardiomyopathy using medical claims data. We derive in 1071 cases non-amyloid failure controls validate three nationally...
New and disruptive building technologies will require new ways of thinking about decision-making design in engineering. The emergence a novel neuroimaging technique, called functional near-infrared spectroscopy (fNIRS), provides approach to quantify engineering cognition. To introduce fNIRS, systematic review was conducted provide an overview methods findings. Researchers interested measuring during infrastructure finance negotiations, coordination among stakeholders, or interaction between...
Abstract The research presented in this paper explores how engineering students cognitively manage concept generation and measures the effects of additional dimensions sustainability on design cognition. Twelve first-year eight senior generated solutions to 10 problems. Half problems included sustainability. number unique developed their neurocognitive activation were measured. Without requirements for sustainability, significantly more than students. First-year recruited higher cortical...
Left atrial (LA) and left ventricular (LV) remodeling are associated with fibrillation (AF). The prospective associations of impairment in cardiac mechanical function, as assessed by speckle-tracking echocardiography, incident AF less clear.In the Cardiovascular Health Study, a community-based cohort older adults, participants free echocardiograms adequate quality for speckle tracking were included. We evaluated indices mechanics (LA reservoir strain, LV longitudinal early diastolic strain...
Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. There is an unmet need to define the and pathogenesis early symptomatic HF, which may be undiagnosed precedes hospitalization.
Treatment persistence is the continuation of therapy over time. It reflects a combination treatment efficacy and tolerability. We aimed to describe real-world rates on disease-modifying therapies (DMTs) for people with multiple sclerosis (pwMS) reasons DMT discontinuation.
Echocardiographic (2-dimensional echocardiography) thresholds indicating disease or impaired functional status compared with normal physiological aging in individuals aged ≥65 years are not clearly defined. In the present study, we sought to establish standard values for 2-dimensional echocardiography parameters related chamber size and function older adults without cardiopulmonary cardiometabolic conditions.
We examined the prevalence of acute kidney injury (AKI) risk factors in emergency medical unit, generated a modified assessment tool and tested its ability to predict AKI.A total 1196 patients admitted admission units were assessed for patient-associated AKI factors. Subsequently, 898 limited number fixed with addition hypotension sepsis. This was correlated episodes.In first cohort, 2.1 ± 2.0 per patient, positive relationship between age higher ≥65 years. In second 12.3% presented or...
This paper presents the results of an experimental study comparing cortical activation in brain when generating solutions using brainstorming, morphological analysis, and TRIZ. Twelve engineering students were given same three design tasks, respectively, solution generation techniques. Students generated while change oxygenated blood along prefrontal cortex (PFC) was measured functional near-infrared spectroscopy. The show that TRIZ leads to differences activation, specifically region...
Abstract This paper presents the results of studying brain activations 30 engineering students when using three different design concept generation techniques: brainstorming, morphological analysis, and TRIZ. Changes in students’ activation prefrontal cortex were measured functional near-infrared spectroscopy. The are based on area under curve analysis oxygenated hemodynamic response as well an assessment connectivity Pearson’s correlation to compare cognitive these ideation techniques....
Green infrastructure solutions like bio-retention systems, permeable pavements, and water harvesting programs are cost-effective for stormwater management more adaptive to a changing climate. However, implementing green is constrained by status quo bias. Status bias inhibits that do not align with industry norms. The research presented in this paper tests how the formal expression of opinion city officials municipal resolution neutralizes effects Engineering graduate students trained were...
Abstract The study presented in this paper applies hidden Markov modeling (HMM) to uncover the recurring patterns within a neural activation dataset collected while designers engaged design concept generation task. HMM uses probabilistic approach that describes data (here, fMRI neuroimaging data) as dynamic sequence of discrete states. Without prior assumptions on data's temporal and spatial properties, enables an automatic inference states neurocognitive are highly likely occur generation....
Abstract Design cognition includes the formulation of problems, generation solutions, and utilization design process strategies. Here, we measure cognitive load to generate solutions engineering challenges for sustainability using functional near-infrared spectroscopy (fNIRS). fNIRS can be used study brain activity in more natural environments, while also providing better spatial resolution than EEG temporal fMRI. It therefore offers new opportunities exploring how relates design. While...
Robust hazard recognition is critical to reducing the estimated 1,000 fatalities and 230,000 injuries in U.S. construction industry each year. By adopting methods from neuroscience, this research develops a more accurate method measure differentiate cognitive response during tasks. The hypothesis that temporal load are influenced by energy source severity. In pilot study, engineering students (n = 14) were shown 24 images total varying (low high) severity type (i.e., gradational, mechanical,...
Ideation is a key phase in engineering design and brainstorming an established method during ideation. The proposal of ideas tends to peak at the beginning process quickly decreases over time. In this preliminary study, we tested innovative solution sustain ideation by providing designers feedback about their neuro-cognition. We used novel neuro-imaging technique called functional near-infrared spectroscopy (fNIRS) monitor students task. Half were given real-time brain activation. Our...
Recent advances in artificial intelligence (AI) enable AI agents to go beyond simply supporting human activities and, instead, take more control team decision-making. While significant literature has studied human-AI collaboration through the lens of as a "second opinion system," this type interaction is not fully representative many human-human scenarios, such scenarios where each decision maker granted equal voting rights for decision. In research, we explore how imparting with impacts...