- Heart Rate Variability and Autonomic Control
- COVID-19 epidemiological studies
- Cardiac Imaging and Diagnostics
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Function and Risk Factors
- Non-Invasive Vital Sign Monitoring
- Data-Driven Disease Surveillance
- Heart Failure Treatment and Management
- Mobile Health and mHealth Applications
- COVID-19 and Mental Health
- Social Media in Health Education
- Ethics in Clinical Research
- Telemedicine and Telehealth Implementation
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Digital Contact Tracing
- ECG Monitoring and Analysis
- COVID-19 and healthcare impacts
- SARS-CoV-2 detection and testing
- Sleep and related disorders
- COVID-19 diagnosis using AI
- Cardiac Health and Mental Health
- Pharmaceutical Practices and Patient Outcomes
- Aortic Thrombus and Embolism
- Coronary Interventions and Diagnostics
Scripps Research Institute
2022-2025
Northwestern University
2014-2024
Scripps (United States)
2024
Scripps Institution of Oceanography
2022-2024
The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology
2024
Scripps Clinic
2023
Torrey Pines Institute For Molecular Studies
2022
Hypertension Institute
2020
Elmhurst College
2020
Cardiovascular Institute of the South
2015
Abstract The annual cost of hospital care services in the US has risen to over $1 trillion despite relatively worse health outcomes compared similar nations. These trends accentuate a growing need for innovative delivery models that reduce costs and improve outcomes. HaH—a program provides patients acute-level at home—has made significant progress past two decades. Technological advancements remote patient monitoring, wearable sensors, information technology infrastructure, multimodal data...
Abstract Background The uptake of nirmatrelvir plus ritonavir (NPR) in patients with coronavirus disease 2019 (COVID-19) has been limited by concerns around the rebound phenomenon despite scarcity evidence its epidemiology. purpose this study was to prospectively compare epidemiology NPR-treated and untreated participants acute COVID-19 infection. Methods We designed a prospective, observational which who tested positive for were clinically eligible NPR recruited be evaluated either viral or...
Abstract To better understand the impact of Long COVID on an individual, we explored changes in daily wearable data (step count, resting heart rate (RHR), and sleep quantity) for up to one year individuals relative their pre-infection baseline among 279 people with 274 without long COVID. Participants COVID, defined as symptoms lasting 30 days or longer, following a SARS-CoV-2 infection had significantly different RHR activity trajectories than those who did not report were also more likely...
Background Abnormalities in left atrial (LA) function often occur before LA structural changes and clinically identified fibrillation (AF). Little is known about the relationship between strain risk of subclinical arrhythmias detected from extended ambulatory cardiac monitoring. Methods Results A total 1441 participants MESA (Multi-Ethnic Study Atherosclerosis) completed speckle-tracking echocardiography monitoring during 2016 to 2018 (mean age, 73 years); AF or entire period were excluded....
Abstract Purpose of Review With the increasing prevalence commercially available wearable digital devices in sleep medicine, this review aims to address some benefits and concerns with using these devices, a specific focus on population-based studies. Recent Findings There has been recent proliferation sleep-related research studies that are likely due their relatively low cost widespread use among consumers. As technology improves, it seems wearables provide information par actigraphy,...
Large language models (LLMs) continue to exhibit noteworthy capabilities across a spectrum of areas, including emerging proficiencies the health care continuum. Successful LLM implementation and adoption depend on digital readiness, modern infrastructure, trained workforce, privacy, an ethical regulatory landscape. These factors can vary significantly ecosystems, dictating choice particular pathway. This perspective discusses 3 pathways—training from scratch pathway (TSP), fine-tuned (FTP),...
This cohort study examines traditional surveillance and self-reported COVID-19 test result data collected from independent smartphone app–based studies in the US Germany.
Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. There is an unmet need to define the and pathogenesis early symptomatic HF, which may be undiagnosed precedes hospitalization.
<sec> <title>BACKGROUND</title> Sleep is an important component of human health and can be measured longitudinally using digital activity trackers. Further, decentralized research data collection has the potential to provide a real-world picture sleep in large populations. We hypothesized that longitudinal patterns from trackers could predict risk obstructive apnea (OSA) similar Berlin questionnaire for hypertension based on self-report. </sec> <title>OBJECTIVE</title> To test ability...
The series of papers in this issue discusses artificial intelligence (AI) for healthcare Canada, including key milestones and efforts, current trends future needs Canada to progress from being a leader AI development responsible ethical adoption that advances the quintuple aim. Three discussion themes support bridge include: datasets, generalizability equity; efficiency evaluation; focusing on system rather than product. Partnerships interdisciplinary teamwork are essential, commentaries...
Traditional viral illness surveillance relies on in-person clinical or laboratory data, paper-based data collection, and outdated technology for transfer aggregation. We aimed to assess whether continuous sensor can provide an early warning signal COVID-19 activity as individual physiological behavioural changes might precede symptom onset, care seeking, diagnostic testing.This multivariable, population-based, modelling study recruited adult (aged ≥18 years) participants living in the USA...
Electronic health record (EHR) technology has become a central digital tool throughout care. EHR systems are responsible for growing number of vital functions hospitals and providers. More recently, patient-facing tools allowing patients to interact with their connect external sources data, such as wearable fitness trackers, personal genomics, outside services, it. As more engaged EHR, the volume variety information will serve an increasingly useful role in care research. Particularly due...
There is a need for better noninvasive remote monitoring solutions that prevent hospitalizations through the early prediction and management of heart failure (HF). SCALE-HF 1 evaluated performance novel Congestion Index alerts to fluid accumulation preceding HF events.
Abstract Background HIV/AIDS negatively impacts poverty alleviation and food security, which reciprocally hinder the rapid scale up effectiveness of HIV care programs. Nyanza province has highest prevalence (15.3%), is third contributor (2.4 million people) to rural in Kenya. Thus, we tested feasibility providing a micro-irrigation pump HIV-positive farmers order evaluate its impact on health economic advancement among patients their families. Methods Thirty enrolled Family AIDS Care...
Abstract Background Recent guidelines from NICE have proposed that open access gastroscopy is largely limited to patients with “alarm” symptoms. Aims and methods This study reviewed the outcome of all our verified oesophageal or gastric carcinoma who presented uncomplicated dyspepsia see if endoscopic investigation warranted in this group. All histologically upper gastrointestinal (GI) cancers over a period 1998 2002 were identified. Their presenting symptoms, treatment, analysed. Results...
Abstract Introduction The uptake of Paxlovid in individuals infected with COVID-19 has been significantly limited by concerns around the rebound phenomenon despite scarcity evidence its epidemiology. purpose this study was to prospectively compare epidemiology treated and untreated participants acute infection Methods We designed a decentralized, digital, prospective observational which who tested positive for using eMed Test-to-Treat telehealth kits were clinically eligible recruited be...