- Art, Politics, and Modernism
- Cinema and Media Studies
- Lung Cancer Treatments and Mutations
- Cultural Industries and Urban Development
- Architecture, Design, and Social History
- Photography and Visual Culture
- Economic Theory and Institutions
- Library Science and Administration
- Web and Library Services
- Shakespeare, Adaptation, and Literary Criticism
- Cancer Genomics and Diagnostics
- Lexicography and Language Studies
- Multiple and Secondary Primary Cancers
- Peptidase Inhibition and Analysis
- Medical Practices and Rehabilitation
- African history and culture analysis
- Hemoglobinopathies and Related Disorders
- Global Health Care Issues
- Muscle and Compartmental Disorders
- Art History and Market Analysis
- Hematopoietic Stem Cell Transplantation
- Museums and Cultural Heritage
- Exercise and Physiological Responses
- Cardiovascular Conditions and Treatments
- Economic and Financial Impacts of Cancer
Seattle Academy of Arts and Sciences
2025
Bedford Hospital
2025
University of Southampton
2022-2024
Medical University of South Carolina
2024
Parsons (United States)
2024
University Hospital Southampton NHS Foundation Trust
2024
National Institute of Allergy and Infectious Diseases
2024
National Marrow Donor Program
2024
National Institutes of Health
2024
Memorial Hospital
2024
PURPOSE The outcome for patients with recurrent medulloblastoma has historically been poor, most dying of disseminated disease. Here, we report on seven medulloblastoma, heavily pretreated a variety chemotherapeutic agents, including parenteral etoposide (VP-16), who showed responses to the administration repeated courses low-dose oral VP-16. PATIENTS AND METHODS Seven age 4 16 years were treated VP-16 after neuroradiographic and clinical evidence tumor progression. Six had received prior...
There is a need for simple, noninvasive solutions to remotely monitor and predict worsening heart failure (HF) events. SCALE-HF 1 (Surveillance Alert-Based Multiparameter Monitoring Reduce Worsening Heart Failure Events) prospective, multicenter study that will develop assess the accuracy of function index-a composite algorithm hemodynamic biomarkers from cardiac scale-in predicting HF events.Approximately 300 patients with chronic recent decompensation be enrolled in this observational...
In youth sports, young people are often subjected to approaches and coach behaviors misaligned with their physical psychological development, including early specialization the use of activity as punishment. Little research investigates these practices from perspective youth. This study used novel qualitative explore student reactions practices. Over four years, students who took an Introduction Psychology class at one private high school in a West Coast city received presentation about...
Human B cell immunity to the influenza hemagglutinin (HA) stem region, a universal vaccine target, is often stereotyped and immunogenetically restricted, posing challenges for study outside humans. Here, we show that macaques vaccinated with HA immunogen elicit human-like public lineages targeting two major conserved sites of vulnerability, central anchor epitopes. Central antibodies were predominantly derived from VH1-138, macaque homolog human VH1-69, VH-gene preferentially used in broadly...
The Nearctic bark beetle genus Scolytus Geoffroy was revised based in part on a molecular and morphological phylogeny. Monophyly of the native species tested using mitochondrial (COI) nuclear (28S, CAD, ArgK) genes 43 characters parsimony Bayesian phylogenetic analyses. Parsimony analyses combined datasets provided mixed results while analysis recovered most nodes with posterior probabilities >90%. Native hardwood- conifer-feeding were as paraphyletic. paraphyletic hardwood-feeding sister to...
Many patients referred with a provisional diagnosis of cancer unknown primary (pCUP) present presumed metastatic disease to the liver. Due lack definitive histological markers, intrahepatic cholangiocarcinoma (iCCA) may be overlooked. This study assessed frequency iCCA within pCUP cohort.A single UK cancer-center sequential from January 2017 April 2020. Baseline diagnostic imaging was reviewed independently by radiologist and oncologist; those radiological features (dominant liver lesion,...
Abstract Background ALL_EARS@UoS is a patient and public involvement engagement (PPIE) group for people with lived experience of hearing loss. The purpose the to share experiences loss healthcare, inform research improve services patients at University Southampton Auditory Implant Service. A year after inception, we wanted critically reflect on value challenges group. Four members were recruited an evaluation steering This paper reports using UK Standards Public Involvement. Methods An...
There is a need for better noninvasive remote monitoring solutions that prevent hospitalizations through the early prediction and management of heart failure (HF). SCALE-HF 1 evaluated performance novel Congestion Index alerts to fluid accumulation preceding HF events.
To assess the accuracy of standard parametric survival models, spline and mixture cure models (MCMs) fitted to overall (OS) data available at time submission in NICE HTA process compared with subsequently made available.Standard distributions, MCMs were OS presented single technology appraisals (TAs) for immune-checkpoint inhibitors (ICIs) cancer. For each TA, estimated from was Kaplan-Meier (KM) that following using differences between point estimates restricted area under curve (AUC) both...
The purpose of this study was to determine the effects carbohydrate supplementation during intense training on dietary patterns, psychological status, and markers anaerobic aerobic performance. Seven members U.S. National Field Hockey Team were matched 7 team counterparts (N = 14). One group blindly administered a drink containing 1 g.kg-1 four times daily, while remaining ingested flavored placebo days training. Subjects underwent pre- posttraining assessments, recorded daily diet intake,...
Lorlatinib is a third-generation anaplastic lymphoma kinase (ALK)/c-ros oncogene 1 (ROS1) tyrosine inhibitor (TKI) with efficacy in patients ALK-rearranged non-small-cell lung cancer (NSCLC) previously treated second-generation ALK or first- and inhibitors. We examined the cost-effectiveness of second- third-line+ (2L+ 3L+) lorlatinib Sweden, versus chemotherapy.
The emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), a phloem-feeding insect from Asia, was identified in 2002 as the cause of widespread (Fraxinus sp.) mortality southeastern Michigan and Essex County, Ontario. Most larvae overwinter nonfeeding prepupae outer sapwood or thick bark large trees. In series studies, we evaluated effects grinding, chipping, heat treatment on survival A. material. Heavily infested bolts containing roughly 8,700 were processed by...