- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
- Diabetes Management and Research
- Thyroid Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Pancreatic function and diabetes
- Hormonal Regulation and Hypertension
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes and associated disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Thyroid and Parathyroid Surgery
- Lipoproteins and Cardiovascular Health
- Thyroid Disorders and Treatments
- Peptidase Inhibition and Analysis
- BRCA gene mutations in cancer
- Regulation of Appetite and Obesity
- Optical Network Technologies
- Parkinson's Disease Mechanisms and Treatments
- Nutrition, Health and Food Behavior
- Cardiovascular Disease and Adiposity
- Growth Hormone and Insulin-like Growth Factors
Sungkyunkwan University
2011-2025
Samsung (South Korea)
2023-2025
University of Hong Kong
2025
Brooklyn Hospital Center
2025
Samsung Changwon Hospital
2024
Dong-A University
2014-2023
Bio-Medical Science (South Korea)
2018
Hanyang University
2018
Dong-A University Hospital
2017
Samsung Medical Center
2011-2014
We evaluated the association of regular physical exercise with presence non-alcoholic fatty liver disease (NAFLD) and enzymes in relation to obesity insulin resistance.A cross-sectional analysis was conducted 72,359 healthy Korean adults without diabetes who participated a comprehensive health check-up. Subjects have been exercising regularly (more than 3 times per week, at least for 30 minutes each time consecutive month) were categorized into group. All subjects deciles based on their body...
Epidemiological studies have demonstrated that excess weight increases the risk of thyroid cancer. However, associations between and prognostic factors for cancer are uncertain. We evaluated relationships body mass index (BMI) clinico-pathological features outcomes papillary (PTC).Retrospective analysis 2057 patients with PTC was performed. Patients were grouped according to BMI (underweight, normal weight, overweight obesity)-based World Health Organization standardized categories. Logistic...
Background Type 2 diabetes (T2D) is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). This study examined the interplay between watching television and T2D genetic of ASCVD. Methods We included 346 916 White British individuals from UK Biobank. A weighted polygenic score was calculated on basis 138 variants associated with T2D. Time spent self‐reported categorized into groups: ≤1 h/d ≥2 h/d. Over median 13.8‐year follow‐up, 21 265 incident ASCVD events were identified....
Diabetes mellitus is a serious and growing health problem worldwide associated with severe acute chronic complications. Moreover, epidemiologic evidence suggests that people diabetes are at significantly higher risk for many forms of cancer. Several studies indicate an association between the liver, pancreas, endometrium, colon/rectum, breast, bladder Mortality also moderately increased in subjects diabetes. Common factors such as age, obesity, physical inactivity smoking may contribute to...
Although papillary thyroid microcarcinoma (PTMC) has a favourable long-term prognosis, disease recurrence after initial treatment remains problem and controversy exists regarding the role of radioactive iodine (RAI) ablation in PTMC. We performed this study to evaluate effect RAI on patients with PTMC.Between 1994 2004, 2579 underwent surgery for cancer at Samsung Medical Center. Among these patients, 704 PTMC presumed disease-free were followed up (median, 64 months; range, 1-185 months)....
We tested the hypothesis that higher levels of bilirubin, a bile pigment with antioxidant properties, are associated decreased risk cardiovascular disease (CVD). This study analyzed data from Korean Health and Genome Study to examine association between serum total bilirubin (TB) on CVD death. Serum TB was measured in 8,844 subjects (4,196 males 4,648 females) evaluated for development new onset 2001 2012 (mean 8.1 years follow-up). During follow-up period, 689 cases incident (7.8%) were...
Glucocorticoids provide a potent therapeutic response and are widely used to treat variety of diseases, including coronavirus disease 2019 (COVID-19) infection. However, the issue glucocorticoid-induced hyperglycemia (GIH), which is observed in over one-third patients treated with glucocorticoids, often neglected. To improve clinical course prognosis diseases that necessitate glucocorticoid therapy, proper management GIH essential. The key pathophysiology includes systemic insulin...
Background/Aims We investigated the clinical characteristics and follow-up findings of subjects with adrenal incidentalomas in a single, tertiary-care hospital South Korea. Methods The study consisted retrospective analysis 282 incidentaloma patients who underwent radiographic endocrinological evaluations at Samsung Medical Center Seoul, Korea, between January 2004 July 2011. Results Most (86.2%) were found to have nonfunctioning tumors. Functioning tumors seen 39 (13.8%). Among them, 28...
Previous studies on adrenal incidentalomas (AIs) are limited by their retrospective design, small numbers of patients, Western populations, or use an outdated imaging technique. We investigated the characteristics AIs in Korean patients and compared them with those reported largest study Italy to discover effects improved techniques ethnicity differences. This was a prospective, multicenter, cross-sectional observational including 1005 patients. Levels plasma adrenocorticotrophic hormone,...
During the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 vaccination-induced hyperglycemia and related complications have been reported. However, there few reports of type 1 diabetes triggered by vaccines in subjects without diabetes. Here, we report case a 56-year-old female patient who developed after second dose mRNA-based vaccination prior history She visited our hospital with uncontrolled despite administration oral hyperglycemic agents. Her initial glycated hemoglobin level...
Purpose: Radioactive iodine therapy (RAI) ≥100 mCi (3.7 GBq) is commonly recommended for papillary thyroid cancer (PTC) patients with extranodal extension (ENE). However, no study has evaluated whether RAI effective in reducing the recurrence of PTC ENE. Methods: This retrospective cohort enrolled 191 ENE who underwent total thyroidectomy and RAI. Recurrence according to activity (<100 vs. mCi) was compared before after propensity score matching (PSM) (1:2) using Kaplan-Meier curves Cox...
Data on the impact of resistance training insulin in overweight or obese children are inconclusive.Thirty South Korean adolescents (mean age 13.10 years) were divided by sex, and then randomly assigned to one three treatment groups, which diet only (DO), with aerobic exercise (AE), (RT) group. Physiologic metabolic parameters assessed at baseline after 12 weeks modification.Both groups (aerobic resistance) showed significant improvements their area under curve sensitivity index values when...