A5101679173- Parkinson's Disease Mechanisms and Treatments
- Bone health and osteoporosis research
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Neurotransmitter Receptor Influence on Behavior
- Lung Cancer Diagnosis and Treatment
- Diet and metabolism studies
- Bone and Joint Diseases
- Neurological disorders and treatments
- Thyroid Cancer Diagnosis and Treatment
- Bone health and treatments
- Regulation of Appetite and Obesity
- Functional Brain Connectivity Studies
- Bone Metabolism and Diseases
- Cardiovascular Disease and Adiposity
- Neuroscience and Neuropharmacology Research
- Diabetes Treatment and Management
- Medical Imaging and Pathology Studies
- Eating Disorders and Behaviors
- Spondyloarthritis Studies and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Thyroid and Parathyroid Surgery
- Adrenal and Paraganglionic Tumors
- Advanced Neuroimaging Techniques and Applications
Pusan National University Hospital
2015-2024
Pusan National University
2010-2021
University of Cincinnati
2013-2021
Biomedical Research Institute
2018
GTx (United States)
2012
Masan National Tuberculosis Hospital
1998
This was a study to compare the diagnostic efficacies of endoscopic ultrasonography (EUS), CT, PET/MR imaging, and PET/CT for preoperative local regional staging esophageal cancer, with postoperative pathologic stage used as reference standard. <b>Methods:</b> During 1 y, 19 patients resectable cancer were enrolled underwent EUS, PET/CT, imaging. A chest radiologist nuclear medicine physician retrospectively reviewed images assigned tumor lymph node stages according seventh version TNM...
Metabolic syndrome (MS) has 2 conflicting factors: obesity known to be protective against osteoporosis and an inflammation that activates bone resorption. The aim of this study was evaluate the difference mineral density(BMD) in women with or without MS according menopausal state. This is a cross-sectional 2,265 women(1,234-premenopausal, 931-postmenopausal) aged over 20 years who visited Health Promotion Center from January 2006 December 2009. We measured BMD at lumbar spine femoral neck....
The aim of this study was to evaluate the usefulness tumor burden as characterized by metabolic volume (MTV) and total lesion glycolysis (TLG) measured F-18 fluoro-2-deoxyglucose (F-18 FDG) PET-computed tomography (CT) in predicting recurrence-free survival (RFS) overall (OS) surgically resected non-small-cell lung cancer (NSCLC) patients.We retrospectively reviewed 91 patients with pathologically documented stages I-IIIA NSCLC. MTV TLG were obtained according various thresholds standard...
The authors investigated relations between obesity, age, and sex the availabilities of striatal dopamine transporter (DAT) extrastriatal serotonin (SERT) by 123I-FP-CIT single-photon emission computed tomography. study population consisted 192 healthy controls with screening scans. Specific bindings to DAT SERT were calculated using regions interest. binding ratios (SBRs) except pons (r = 0.2217, p 0.0026), not correlated body mass index (BMI). SBRs midbrains negatively BMIs obese subjects...
The clinical diagnosis of Kennedy's disease (KD) is not easy when the typical manifestations are lacking, especially in early stage disease. In our study, we tried to identify relative frequency common features and symptoms KD.Eighteen Korean patients with KD were included. Clinical findings subdivided into two parts: age at onset each characteristic signs on investigations. With detailed examinations, serum creatine kinase (CK) level, electrophysiologic study DNA analysis performed analyzed...
Objective The goal of the present study was to determine whether volumetric parameters such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG) measured by 18F-FDG PET/CT could be used prognostic factors for recurrence-free survival (RFS) overall (OS) in patients with surgically resected rectal cancer. Patients Methods A retrospective review identified 73 cancer who received PET/CT. Survival analysis conducted using Kaplan-Meier analysis, curves stratified age, sex, lymph node...
The purpose of this study was to investigate correlations between diffuse splenic FDG uptake and hematological inflammatory parameters clarify the significance on PET/CT images.We retrospectively analyzed consecutive records F-18 scans selected 31 patients with as patient group. A total 25 who underwent for simple health checkup were enrolled control ROIs placed liver spleen measure maximal standardized value (SUVmax). SUVmax divided by calculate spleen/liver ratio. S/L ratio various...
The purpose of this study was to evaluate the accuracy F-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) imaging in detection malignant pleural effusion and metastasis patients with non-small cell lung cancer (NSCLC).We analyzed PET/CT images 33 effusion. We used 2 categorical parameters differentiate from benign effusion: i) quantitative using maximum standardized uptake value (SUVmax pleura, following ratios: lesion aorta (L/Ao), cerebellum (L/Cbl),...
The aim of the current study was to investigate predictive value metabolic tumor volume (MTV) measured by (18)F-FDG PET/CT for regional lymph node (rLN) metastasis in patients with esophageal cancer.A retrospective review identified 54 surgically resected cancer who received at diagnosis cancer. findings all primary and rLN involvement were compared pathologic within 5 weeks after surgical resection. diagnoses state confirmed Univariate multivariate analyses used analyze associations among...
Background This study was a multicenter, parallel-group, double-blind, double-dummy, randomized, noninferiority trial to evaluate the efficacy and safety of γ-linolenic acid (GLA) relative α-lipoic (ALA) over 12-week treatment period in type 2 diabetes mellitus (T2DM) patients with painful diabetic peripheral neuropathy (DPN). Methods included 100 T2DM between 20 75 years age who had DPN received either GLA (320 mg/day) placebo or ALA (600 for 12 weeks. The primary outcome measures were mean...
Background This phase 3 study evaluated the efficacy and safety of 6-month treatment with romosozumab in Korean postmenopausal women osteoporosis. Methods Sixty-seven osteoporosis (bone mineral density [BMD] T-scores ≤−2.5 at lumbar spine, total hip, or femoral neck) were randomized (1:1) to receive monthly subcutaneous injections (210 mg; n=34) placebo (n=33) for 6 months. Results At month 6, difference least square (LS) mean percent change from baseline spine BMD (primary endpoint) between...
Abstract We evaluated the associations between metabolic parameters with visceral adipose tissue (VAT) volume in women prediabetes or type 2 diabetes (T2DM), and we compared VAT area. enrolled aged > 20 years T2DM, who underwent oral glucose tolerance test whose was using computed tomography (CT) at our institution 2017 2019. All participants unenhanced spiral CT a 3-mm slice thickness from level of diaphragm to mid-thigh. The two areas were defined as free drawn area on levels umbilicus...
We aimed to develop a decision tree model improve diagnostic performance of positron emission tomography/computed tomography (PET/CT) detect metastatic lymph nodes (LN) in non-small cell lung cancer (NSCLC). 115 patients with NSCLC were included this study. The training dataset 66 patients. A was developed 9 variables, and validated 49 patients: short long diameters LNs, ratio diameters, maximum standardized uptake value (SUVmax) LN, mean hounsfield unit, LN SUVmax ascending aorta (LN/AA),...
Objectives Concurrent inflammation or anemia at the time of PET/computed tomography (CT) could be one several causes diffuse splenic 18F-fluorodeoxyglucose (18F-FDG) uptake. In this study, we focused on cytokines to investigate interactions during phenomenon and clarify significance 18F-FDG uptake in PET/CT. Methods We selected 40 patients (17 women 23 men) with cholangiocarcinoma, pancreatic cancer, gallbladder cancer who had undergone These were subdivided into two groups (group A: showing...
The aim of the current study was to investigate predictive value dual-time-point F-18 FDG PET/CT for pathologic N1 metastasis in patients with non-small cell lung cancer (NSCLC).A retrospective review identified 70 NSCLC who received at diagnosis cancer. findings all primary and mediastinal lymph node involvement were compared within 5 weeks after surgical resection. diagnoses state confirmed by Univariate multivariate analyses used analyze associations among status age, sex, tumor size,...
We aimed to evaluate the associations of visceral adiposity with cardiometabolic risk factors in normal subjects integrated 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT). A total 58 who underwent 18F-FDG PET/CT scan for cancer screening were included this study. Volume and average Hounsfield unit (HU) adipose tissue (VAT) was measured from CT components PET/CT. Standardized uptake values (SUVmax) liver, spleen, lumbar spine ascending aorta (AA) PET Body mass...