The optimum dosage for vitamin D supplementation has not yet been elucidated in patients with Ulcerative colitis (UC). aim of this study was to investigate the effects two regimens UC deficiency. In double blind randomized clinical trial, 50 mild moderate UC, who met inclusion criteria, received either 1000 or 2000 IU/day (as low dose high group, respectively) 12 weeks. Serum 25-hydroxy (25-OHD) level, total antioxidant capacity (TAC), and Total Oxidant Status (TOS), inflammatory bowel...

Liver cirrhosis is associated with significant nutritional risks and poor survival rates. Little known about the impact of dietary factors on metabolic complications mortality from cirrhosis.The present study investigated potential associations between fibers risk cirrhosis-related mortality.In this prospective study, 121 ambulatory cirrhotic patients more than six months diagnosis were followed-up for 4 years. Dietary intakes assessed using a 168-item semi-quantitative validated food...

The aim of this study was to determine the effects caffeine and chlorogenic acid supplementation on gut microbiota, metabolic disturbances in patients with NAFLD diabetes. In randomized, placebo-controlled, clinical trial, 26 diabetes were randomly assigned four groups receive either 200 mg plus (CFCA), or placebo (starch) (CFPL), (CAPL), (PLPL) for 12 weeks. After 3 months supplementation, intervention showed a significant decrease body weight (CFCA group =-3.69 kg; CFPL group=-0.7kg; CAPL...

Abstract Background Cirrhosis is a medical condition marked by persistent liver damage, which leads to the development of fibrous tissue and compromised function. In present study, we decided investigate possibility connection between consumption fermentable olig-, di-, monosaccharides, polyols (FODMAPs) mortality rates in cirrhotic patients utilizing data obtained from prospective cohort study. Methods This study enrolled 166 ambulatory two hospitals Tehran, Iran, 2016 2018, followed them...

The role of diet in reducing the burden liver disease and mortality attributed to cirrhosis is very imperative. present study scrutinized relationship between dietary advanced glycation end products (AGEs) patients with cirrhosis. This research was a prospective cohort on 166 ambulatory cirrhotic who had been diagnosed for maximum six months. Follow-up continued 5 years until May 2024. To determine incidence quartiles AGEs, cox regression models were used adjustment potential confounding...

Background A double blind clinical trial was performed to evaluate whether the polycystic ovary syndrome (PCOS)-specific serum markers and metabolic parameters would change in women with PCOS during three-month administration of oligopin. Methods In this double-blind multicenter trial, we randomly assigned 80 women, based on a 1:1 ratio, receive oligopin (n= 40) or maltodextrin as placebo (n = for up 3 months. As PCOS-specific outcomes, investigated changes testosterone, sex hormone binding...

Abstract Background Liver cirrhosis is a worldwide burden and associated with poor clinical outcomes, including increased mortality. The beneficial effects of dietary modifications in reducing morbidity mortality are inevitable. Aim current study aimed to evaluate the potential association protein intake cirrhosis-related Methods In this cohort study, 121 ambulatory cirrhotic patients at least 6 months diagnosis were followed-up for 48 months. A 168-item validated food frequency...

Although previous findings have shown the beneficial role of healthy eating pattern on human immune system, association between plant-based diet and COVID-19 severity has not yet been elucidated. This study aimed to determine possible index (PDI) in severity. cross-sectional, multicentral was conducted 141 patients with confirmed COVID-19. Dietary intakes were evaluated using a validated food frequency questionnaire. Then, PDI compared who needed be hospitalised (considered severe cases),...

Abstract As a global health concern, cirrhosis contributes significantly to morbidity and mortality. This prospective cohort study aimed investigate the association between dietary acid load (DAL) cirrhosis-related Present was conducted on 121 patients with newly diagnosed who were followed up for 48 months. Anthropometric measures, nutritional status intakes assessed DAL estimated based potential renal (PRAL) net endogenous production (NEAP) scores. Crude multivariable-adjusted hazard...

Background: Type 2 Diabetes mellitus (T2DM) is a prevalent chronic condition causing one-fifth million deaths globally. Standard treatments for diabetes are not sufficiently effective, highlighting the need to find adjunctive improve glycemic control. Nigella sativa (NS) and Cuminum cyminum (CC) two herbal medicines known their antioxidant, anti-inflammatory, antidiabetic properties. Objective: This study aims assess impact of supplementation with combination NS CC on regulation among...

Liver Cirrhosis, defined as the final stage of chronic liver disease, may become more prevalent in lower level body defense against oxidation and inflammation. Therefore, we assessed association dietary total antioxidant capacity (DTAC) with severity mortality cirrhosis a cohort study. 120 newly diagnosed patients from Tehran, Iran, participated this The patients' habitual diet was using 168-item validated food frequency questionnaire. Both ferric-reducing potential (FRAP) oxygen radical...

Background and Aims: Although irritable bowel syndrome is one of the most common gastrointestinal disorders presented to gastroenterologists, therapeutic strategies are not yet well-established. Accordingly, we conducted a randomized, double-blind, placebo-controlled, clinical trial evaluate possible superiority adding glutamine supplement low fermentable oligo- di- monosaccharides polyols (FODMAP) diet in patients with (IBS). Methods: Eligible adults were randomized receive FODMAP either...

Background: Previous research declares that metabolic syndrome (MS) is a cluster of risk factors contribute to significant level incidence cardiovascular diseases and diabetes mellitus. Lichen Planus (LP) potential factor affect dyslipidemia other components MS. Objectives: The aim this was assess the association MS, dyslipidemia, weight, hypertension, mellitus with cutaneous LP. Methods: To reach goal research, case-control study designed. sample included 140 participants dividing into two...

Given the importance of dietary habits in immune system, current study aimed at investigating association between Dietary Approach to Stop Hypertension (DASH) diet and risk hospitalization due COVID-19.Dietary data 141 patients with COVID-19 were collected using 147-item food frequency questionnaire. DASH score this cross-sectional was calculated based on eight components, including fruits, vegetables, legumes nuts seeds, whole grains, low-fat dairy, red or processed meats, sweetened...

Abstract Considering the progressive prevalence and co-occurrence of type 2 diabetes mellitus (T2DM) non-alcoholic fatty liver disease (NAFLD), as well current evidence suggesting elevated levels basal metabolic rate (BMR) among these individuals, present study aimed to identify factors determining hypermetabolism in such subjects. This cross sectional was conducted 30 53-year-old individuals with concurrent T2DM NAFLD (controlled attenuation parameter score ≥ 260 dB/m). Resting energy...

Growing clinical evidence represented that certain dietary components are involved in inflammatory bowel disease (IBD) development and progression. This research, therefore, aimed to evaluate whether there exists any relationship between nutrients IBD. case-control study from 2017 2019 was performed on 145 newly diagnosed IBD patients BMI-, sex-, age-matched healthy controls who were recruited a hospital clinic. A validated 168-item food frequency questionnaire completed by each participant....

The aim of this study was to investigate whether dairy intake associated with the severity coronavirus disease 2019 (COVID-19) and probability hospitalization patients. This cross-sectional conducted on 141 patients COVID-19 an average age 46.23 ± 15.88 years. number men (52.5%) participating in higher than that women. association between evaluated by multivariable logistic regression analysis. risk highest tertile 31% lower lowest (odds ratio [OR], 0.69; 95% confidence interval [CI],...

Abstract Since conducting a long-term randomised clinical trial is not logical and feasible to find the optimum dosage of salt intake in patients with cirrhosis, cohort studies are best design assess effects dietary on survival cirrhotic patients. This study aimed evaluate association between mortality risk The present was designed as three referral hospitals Iran 2018. One hundred twenty-one aged 20 70 years established cirrhosis were recruited. Dietary intakes, demographic data disease...