A5100633654- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Cancer-related molecular mechanisms research
- Adenosine and Purinergic Signaling
- Lipoproteins and Cardiovascular Health
- Sulfur Compounds in Biology
- MicroRNA in disease regulation
- Eicosanoids and Hypertension Pharmacology
- Organ Transplantation Techniques and Outcomes
- Clinical Nutrition and Gastroenterology
- Renin-Angiotensin System Studies
- Viral Infections and Vectors
- COVID-19 Impact on Reproduction
- Peroxisome Proliferator-Activated Receptors
- Thyroid Cancer Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Cancer, Lipids, and Metabolism
- Extracellular vesicles in disease
- Congenital Diaphragmatic Hernia Studies
Hainan Medical University
2020
Nanjing Medical University
2010-2019
China Medical University
2006-2008
Atherosclerosis is associated with reduced vascular hydrogen sulfide (H2 S) biosynthesis. GYY4137 a novel slow-releasing H2 S compound that may effectively mimic the time course of release in vivo. However, it not known whether affects atherosclerosis.RAW 264.7 cells and human blood monocyte-derived macrophages were incubated oxidized low density lipoprotein (ox-LDL) with/without GYY4137. ApoE(-/-) mice fed high-fat diet for 4 weeks administered 30 days. Lipid atherosclerotic lesions...
Thyroid cancers are the most common malignancy of endocrine system; however, there is no reliable blood biomarkers for thyroid cancer diagnosis and even aggressive nonaggressive as well benign nodule discrimination. The present study aimed at evaluating whether circulating microRNA (miRNA) can differentiate from nodules. In this study, we performed a multiphase, case-control to screen serum miRNA expression profile in 100 patients with papillary (PTC), 15 medullary carcinoma (MTC), 91...
Abstract Asthenozoospermia is one of the major causes human male infertility. Long noncoding RNAs (lncRNAs) play critical roles in spermatogenesis processes. The present study aims to investigate intricate regulatory network associated with asthenozoospermia. lncRNAs expression profile was analyzed asthenozoospermia seminal plasma exosomes by RNA-sequencing, and functions differentially expressed genes (DEGs) were Gene Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) pathway DO (Disease...
Background: Emerging and re-emerging infectious diseases (EIDs Re-EIDs) cause significant economic crises public health problems worldwide. Epidemics appear to be more frequent, complex, harder prevent. Early warning systems can significantly reduce outbreak response times, contributing better patient outcomes. Improving early methods might one of the most effective responses. This study employs a bibliometric analysis dissect global research hotspots evolutionary trends in field disease...
To investigate the dynamic change and role of neuronal nitric oxide synthase (nNOS) inducible (iNOS) in neonatal rat with intestinal injury to define whether necrotizing enterocolitis (NEC) is associated levels (NOS) mucosa affected intestine tissue.Wistar rats less than 24 h age received an intraperitoneal injection 5 mg/kg lipopolysaccharide (LPS). Ileum tissues were collected at 1, 3, 6, 12 following LPS challenge for histological evaluation NEC measurements nNOS iNOS. The correlation...
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in premature neonates. The pathogenesis of NEC remains poorly understood. present study aimed to investigate dynamic change and role cyclooxygenase-2 (COX-2) neonatal rats with intestinal injury. Wistar rats, <24 h age, received an intraperitoneal injection 5 mg/kg lipopolysaccharide (LPS). Ileal tissues were collected at 1, 3, 6, 12 24 following LPS challenge for histological evaluation measurements COX-2 mRNA....
Objective To determine the dynamic changes of ileum epidermal growth factor(EGF),transforming factor-α(TGF-α)and epithelial factor receptor(EGFR)in neonatal rats with intestinal injury and to investigate their role in necrotizing enterocolitis(NEC). Methods One-day-old Wistar rat pups were divided into two groups.The lipopolysaccharide(LPS)-injected group(n=40)received an intraperitoneal injection 5 mg/kg LPS those control group(n=8)did not.Control group LPS-injected at 1,3,6,12 24 h...