A5048037528- Functional Brain Connectivity Studies
- Sleep and related disorders
- Heart Rate Variability and Autonomic Control
- Electromagnetic Scattering and Analysis
- Neural and Behavioral Psychology Studies
- Dietary Effects on Health
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Liver Disease Diagnosis and Treatment
- Nutritional Studies and Diet
- Integrated Circuits and Semiconductor Failure Analysis
- Anesthesia and Pain Management
- Misinformation and Its Impacts
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Surface and Thin Film Phenomena
- Transcranial Magnetic Stimulation Studies
- Sleep and Wakefulness Research
- Drug-Induced Adverse Reactions
- Ultrasonics and Acoustic Wave Propagation
- Circadian rhythm and melatonin
- Biofield Effects and Biophysics
- Mental Health Research Topics
- Mindfulness and Compassion Interventions
- Dental Anxiety and Anesthesia Techniques
Peking University
2020-2025
Peking University Sixth Hospital
2020-2025
First Affiliated Hospital of Zhengzhou University
2025
Xi'an Jiaotong University
2020-2024
Shaanxi University of Chinese Medicine
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023
Third Affiliated Hospital of Sun Yat-sen University
2020-2022
Sun Yat-sen University
2020-2022
National Clinical Research
2020
Henan Polytechnic University
2015
Mounting evidence indicates that circular RNAs (circRNAs) have essential roles in several diseases, including periodontitis. Periodontal ligament stem cells (PDLSCs) exhibit potential for treating periodontitis accompanied by hypoxia. However, it is unclear how circRNA affects the osteogenesis of PDLSCs under In this study, a novel circRNA, hsa_circ_0003489, was found located at gene cyclin-dependent kinase 8 (CDK8) and referred to as circCDK8. The expression levels circCDK8...
The present study assessed the willingness of general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy resistance. A national online survey was conducted from 29 January 2021 26 April in China. Multinomial logistic regression analyses were identify Of 34,041 participants surveyed, 18,810 (55.3%) willing get vaccinated, 13,736 (40.3%) hesitant, 1495 (4.4%) resistant. Rates acceptance increased over time, with geographical discrepancies resistance...
BACKGROUND: The impact of different ovarian stimulation (OS) protocols on endometrial receptivity remains controversial. In this study, the effects OS expression integrin β3 subunit and leukaemia-inhibitory factor (LIF) during implantation window rate in mice were investigated. METHODS: Three used, involving either pregnant mare's serum gonadotrophin (PMSG) alone, PMSG plus GnRH agonist or antagonist. Uterus samples collected at 48 h after ovulation detected with immunohistochemistry,...
Background: The COVID-19 pandemic is our generation's greatest global challenge to public health system. Vaccines are considered one of the most effective tools available for preventing infection and its complications sequelae. Understanding addressing psychological stress related vaccination may promote acceptance these vaccines. Methods: We conducted an online survey from January 29 April 26, 2021 explore levels among general in China. Participants were asked evaluate their considering...
Late-life depression (LLD) is an important public health problem among the aging population. Recent studies found that mindfulness-based cognitive therapy (MBCT) can effectively alleviate depressive symptoms in major disorder. The present study explored clinical effect and potential neuroimaging mechanism of MBCT treatment LLD. We enrolled 60 participants with LLD 8-week, randomized, controlled trial (ChiCTR1800017725). Patients were randomized to treatment-as-usual (TAU) group or a MBCT+TAU...
The present study investigated functional connectivity and white matter integrity of the fronto-parietal network (FPN) to reveal neural mechanisms that underlie late-life depression (LLD). Fifty patients with LLD 40 non-depressed controls were included in study. A multi-parametric approach was used by applying independent component analysis (ICA) estimate FPN tractbased spatial statistics examine white-matter tracts FPN. Patients exhibited abnormalities right inferior frontal gyrus, middle...
Abstract Perceived stress impairs cognitive function across the adult lifespan, but extent to which cognition decline is variable individuals. Individual differences in response are described as personality traits. Substantial individual magnitude of impairment that induced by short-term perceived poorly understood. The present study tested hypothesis relationship between and different aspects mediated included 1066 participants with behavior neuroimaging data from Human Connectome Project...
Chronic pain and sleep disturbance are highly comorbid disorders, which leads to barriers treatment significant healthcare costs. Understanding the underlying genetic neural mechanisms of interplay between chronic is likely lead better treatment. In this study, we combined 1206 participants with phenotype data, resting-state functional magnetic resonance imaging (rfMRI) data genotype from Human Connectome Project two large sample size genome-wide association studies (GWASs) summary published...
ABSTRACT Background Some studies have shown that gut microbiota may be associated with intervertebral disc degeneration. However, the causal effects between and IVDD whether blood metabolites act as a mediator remain unclear. The objective of this study was to investigate relationship herniation, focus on potential mediating role metabolites. Methods Gut microbiota, metabolites, data were identified from large‐scale genome‐wide association (GWAS) summary data. Then we used Mendelian...
Subclinical anxiety, depressive and somatic symptoms appear closely related. However, it remains unclear whether mediate the association between subclinical anxiety what underlying neuroimaging mechanisms are for mediating effect.Data of healthy participants (n = 466) in remission major disorder 53) were obtained from Human Connectome Project. The Achenbach Adult Self-Report was adopted to assess symptoms. All completed four runs resting-state functional magnetic resonance imaging. Mediation...
Background: Several epidemiological studies have reported the protective role of caffeine on health outcomes; however, it remained debatable consumption and brain amyloid positivity. Objective: We aimed to determine relationship between pathology in cognitively normal older adults. Methods: The dataset used for analysis this cross-sectional study was selected from Anti-Amyloid Treatment Asymptomatic Alzheimer’s (A4) Study. Multivariable logistic regression analyses were performed explore...
We report the results of a grazing-incidence x-ray study on order-disorder phase transition (111)-oriented ${\mathrm{Cu}}_{3}$Au film (0.7 \ensuremath{\mu}m) epitaxially grown an ${\mathrm{Al}}_{2}$${\mathrm{O}}_{3}$ substrate with Nb buffer layer. By varying incident beam angles to surface, penetration depths between 22 and 650 A\r{} were probed. While bulk disorders at ${T}_{c}^{b}$=665 K through first-order transition, surface region appears exhibit enhanced ordering slightly higher...
To explore the correlation and causality between multidimensional sleep traits pan-cancer incidence mortality among patients with cancer. The multivariable Cox regression, linear nonlinear Mendelian randomization (MR), survival curve analyses were conducted to assess impacts of chronotype, duration, insomnia symptoms on risk (N = 326,417 from United Kingdom Biobank) 23,956 Biobank). In we observed a J-shaped association duration cancer respectively. addition, there was positive (HR, 1.03,...
Negative bias of emotional face is the core feature depression, but its underlying neurobiological mechanism still unclear. The neuroimaging findings negative recognition and depressive symptoms are inconsistent. neural association between were analyzed by measuring associations resting state functional connectivity (FC), brain structures, bias, problems. Then, we performed a mediation analysis to assess potential overlapping mechanisms. We found correlation recognition. Secondly, structure...
We have developed an x-ray-diffraction technique that provides depth sensitivity to the near-interface region of a thick, nonregistered film. By measuring intensity profiles along Si[00l] substrate crystal truncation rods, we compare diffraction from Si/GaAs interface with model based on grid misfit dislocations. find atoms root-mean-square displacement 1.09\ifmmode\pm\else\textpm\fi{}0.10 \AA{} and has roughness 2.9\ifmmode\pm\else\textpm\fi{}1.0 \AA{}. The indicates anomalously small...
STUDY QUESTIONHow does the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology (ART) compare with these control from spontaneous pregnancies?
The functional connectivity within and between networks could provide a framework to characterize the neurobiological mechanism of nicotine addiction. This study examined brain regions that were functionally connected in response smoking cues established brain-behaviour relationships smokers. Sixty-seven male smokers enrolled scanned while performing cue-reactivity Stroop task. A whole-brain analysis approach, connectome-based predictive modelling (CPM), was conducted on data from task...