A5049883607- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Sleep and related disorders
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Cancer-related molecular mechanisms research
- Dementia and Cognitive Impairment Research
- Cancer, Lipids, and Metabolism
- Sleep and Wakefulness Research
- COVID-19 Clinical Research Studies
- MicroRNA in disease regulation
- RNA Research and Splicing
- Treatment of Major Depression
- Obstructive Sleep Apnea Research
- Intensive Care Unit Cognitive Disorders
- Health disparities and outcomes
- Bipolar Disorder and Treatment
- Psychological Well-being and Life Satisfaction
- Misinformation and Its Impacts
- Estrogen and related hormone effects
- Functional Brain Connectivity Studies
- Diet and metabolism studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Immune Cell Function and Interaction
- Prostate Cancer Treatment and Research
Affiliated Hospital of North Sichuan Medical College
2024-2025
Peking University
2019-2025
Peking University Sixth Hospital
2019-2025
Center for Life Sciences
2021-2025
Chinese Institute for Brain Research
2021-2025
Shandong Provincial Hospital
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Chongqing Medical University
2020-2024
Temple University
2024
Coronavirus disease 2019 (COVID-19) has evolved into a worldwide pandemic, and been found to be closely associated with mental neurological disorders. We aimed comprehensively quantify the association between disorders, both pre-existing subsequent, risk of susceptibility, severity mortality COVID-19.In this systematic review meta-analysis, we searched PubMed, Web Science, Embase, PsycINFO, Cochrane library databases for studies published from inception up January 16, 2021 updated at July 7,...
Leisure activities are major components of modifiable and healthy lifestyles proposed to help prevent the development dementia. This study aimed assess effects different types leisure activities, including cognitive, physical, social on incidence all-cause dementia (ACD), Alzheimer disease (AD), vascular (VD).We performed a systematic review meta-analysis Cochrane, PubMed, Embase, Web Science databases identify longitudinal studies that examined associations between Relative risks (RRs) 95%...
The concept of a healthy lifestyle is receiving increasing attention. This study sought to identify an optimal profile associated with sleep health in general population China. An online cross-sectional survey was conducted from June July 2022. Six factors were assessed: diet, regular physical exercise, never smoking, drinking alcohol, low sedentary behavior, and normal weight. Participants categorized into the (5-6 factors), average (3-4 unhealthy groups (0-2 factors). study's primary...
COVID-19 might have long-term mental health impacts. We aim to investigate the longitudinal changes in problems from initial peak its aftermath among general public China. Depression, anxiety and insomnia were assessed a large-sample nationwide cohort of 10,492 adults during (28 February 2020 11 March 2020) (8 July 8 August using Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Insomnia Severity Index. used generalized estimating equations linear mixed models explore factors...
The present study assessed the willingness of general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy resistance. A national online survey was conducted from 29 January 2021 26 April in China. Multinomial logistic regression analyses were identify Of 34,041 participants surveyed, 18,810 (55.3%) willing get vaccinated, 13,736 (40.3%) hesitant, 1495 (4.4%) resistant. Rates acceptance increased over time, with geographical discrepancies resistance...
The relationship between Metabolic Syndrome and cancer remains controversial. We aimed to assess the association risk at different locations using a Mendelian randomization approach.
Abstract Backgound Although Myeloid-derived suppressor cells (MDSCs) have a prominent ability to suppress the immune responses of T lymphocytes and propel tumor escape, lack profound systemic immunesuppression in tumor-bearing mice patients. The underlying mechanism these remains unclear. Methods For this purpose, renal cancer-derived exosomes (RDEs) were first labeled with PKH67 been observed internalization by MDSCs. Flow cytometry analysis showed proportion activity change MDSCs spleen...
Background: The COVID-19 pandemic is our generation's greatest global challenge to public health system. Vaccines are considered one of the most effective tools available for preventing infection and its complications sequelae. Understanding addressing psychological stress related vaccination may promote acceptance these vaccines. Methods: We conducted an online survey from January 29 April 26, 2021 explore levels among general in China. Participants were asked evaluate their considering...
Abstract The present study aimed to evaluate the relationship between OSA and adenotonsillar size in children of different weight status. A total 451 patients aged 2–13 years with suspected were retrospectively enrolled study. Correlations apnea-hypopnea index (AHI) status investigated. adenoidal/nasopharyngeal (A/N) ratio underweight was significantly higher than that normal-weight ( P = 0.027). Both adenoid tonsil positively correlated logAHI normal (r 0.210, 0.001; r 0.212, 0.001) but...
Abstract Background Dementia is a global public health priority. Many modifiable factors have been shown to influence the development of dementia, but these are not adequately known by general public. This study aimed assess awareness that associated with dementia in China. Methods A cross-sectional was conducted from May October 2019 using an Internet-based questionnaire. Data on basic sociodemographic characteristics were collected, and knowledge risk protective for investigated. Logistic...
Background: The novel coronavirus 2019 (COVID-19) pandemic and related compulsory measures have triggered a wide range of psychological issues. However, the effect COVID-19 on mental health in late-middle-aged adults remains unclear. Methods: This cross-sectional, web-based survey recruited 3,730 participants (≥ 50 years old) between February 28 March 11 2020. Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Insomnia Severity Index, Acute Stress Disorder Scale were used to...
Prostate cancer (PCa) is a common malignant in elderly males Western countries. Whole-genome sequencing confirmed that long non-coding RNAs (lncRNAs) are frequently altered castration-resistant prostate (CRPC) and promote drug resistance to therapy. Therefore, elucidating the prospective role of lncRNAs PCa oncogenesis progression remarkable clinical significance. In this study, gene expression tissues was determined using RNA-sequencing datasets, diagnostic prognostic values CRPC were...