A5013658294- Gut microbiota and health
- Cancer-related Molecular Pathways
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Mycobacterium research and diagnosis
- Eosinophilic Esophagitis
- Genomics and Phylogenetic Studies
- Infectious Diseases and Mycology
- Cancer Genomics and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Cancer Immunotherapy and Biomarkers
- Drug Transport and Resistance Mechanisms
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Angiogenesis and VEGF in Cancer
- Agriculture, Soil, Plant Science
- Liver Disease Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- Diagnosis and Treatment of Venous Diseases
- Cancer Research and Treatments
- Diverticular Disease and Complications
National University of Singapore
2022-2024
Keio University
2020-2021
Immune cells and tumor vessels constitute important elements in tissue; however, their detailed relationship human tumors, including HCC, is still largely unknown. Consequently, we expanded our previous study on the immune microenvironment of HCC analyzed among microenvironment, inflammatory/angiostatic factor expression, angiogenic vessel findings, encapsulating clusters (VETC) macrotrabecular-massive (MTM) patterns.We classified into four distinct immunovascular subtypes...
Telomerase reverse transcriptase ( TERT ) promoter mutations are frequently observed in hepatocellular carcinoma (HCC); however, the impact of (TPMs) on clinical features and morphological patterns HCC remains unresolved. Using DNA extracted from 97 HCCs, correlations between TPM status both immunohistochemically‐based subgroups were evaluated. Morphological tumor semi‐quantitatively analyzed using hematoxylin eosin‐stained slides whole cross‐sectional area. The percentages area occupied by...
Automated nucleic acid extractors are useful instruments for the high-throughput processing of bio-samples and expected to improve research throughput in addition decreased inter-sample variability inherent manual processing. We evaluated three commercial Bioer GenePure Pro (Bioer Technology, Hangzhou, China), Maxwell RSC 16 (Promega Corporation, Madison, WI, USA), KingFisher Apex (ThermoFisher Scientific, Waltham, MA, USA) based on their DNA yield, purity, 16S rRNA gene amplicon results...
Hepatocellular carcinoma (HCC) remains a leading cause of cancer death worldwide despite recent advances in surveillance and therapeutic management. The outcomes for HCC patients remain poor, often as result late diagnosis or lack effective treatments. Early detection precise are evidently crucial improving the prognosis HCC. However, is highly heterogeneous with various clinical backgrounds altered molecular pathways; these factors make its more difficult. Approximately 25% HCCs harbor...