A5050127714- Organic Light-Emitting Diodes Research
- Organic Electronics and Photovoltaics
- Luminescence and Fluorescent Materials
- Alzheimer's disease research and treatments
- Luminescence Properties of Advanced Materials
- Advanced Photocatalysis Techniques
- Color perception and design
- Auditing, Earnings Management, Governance
- Surgical Sutures and Adhesives
- 3D Printing in Biomedical Research
- Reconstructive Surgery and Microvascular Techniques
- Nerve injury and regeneration
- Medical Research and Treatments
- Advanced ceramic materials synthesis
- Risk Management in Financial Firms
- Green IT and Sustainability
- Tissue Engineering and Regenerative Medicine
- Supramolecular Self-Assembly in Materials
- Mental Health Research Topics
- Reconstructive Facial Surgery Techniques
- Superconducting Materials and Applications
- Bioinformatics and Genomic Networks
- Perovskite Materials and Applications
- Advanced Nanomaterials in Catalysis
- Ergonomics and Musculoskeletal Disorders
Neijiang Normal University
2025
University of California, San Francisco
2016-2025
Yunnan University
2025
Hefei Institutes of Physical Science
2024
Institute of Plasma Physics
2024
Chinese Academy of Sciences
2007-2024
Minzu University of China
2024
South China University of Technology
2019-2023
State Key Laboratory of Luminescent Materials and Devices
2019-2023
Ningbo First Hospital
2019-2023
Significance An expanding body of evidence argues that the Aβ and tau proteins share important characteristics prion propagation to cause pathogenesis in Alzheimer’s disease (AD). form a number amyloids (β-sheet–rich structures) with distinct conformations (“strains”), some which give rise different diseases associated pathologies. We develop new probes amyloid structure use these identify conformational strains heritable sporadic forms AD patient samples. demonstrate can be discerned types,...
Abstract Recent studies have shown the importance of cell–substrate interaction on neurone outgrowth, where Young’s modulus matrix plays a crucial role neurite length, migration, proliferation, and morphology neurones. In present study, PC12 cells were selected as representative to be cultured hydrogel substrates with different stiffness explore effect substrate outgrowth. By adjusting concentration gelatin methacryloyl (GelMA), variation stiffnesses (indicated by modulus) from approximately...
Abstract The operational lifetime of blue organic light‐emitting diodes (OLEDs) is still insufficient for practical applications in lighting and display. One type emitting materials with hybridized local charge‐transfer (HLCT) process are beneficial achieving high‐efficiency OLEDs through “hot exciton” channel by harnessing high‐lying triplet (T n ) excitons. However, the resulting rarely studied understood. In this article, aging properties fluorescent based on an HLCT material...
In neurodegenerative diseases, proteins fold into amyloid structures with distinct conformations (strains) that are characteristic of different diseases. However, there is a need to rapidly identify in situ. Here, we use machine learning on the full information available fluorescent excitation/emission spectra amyloid-binding dyes six conformational strains vitro, as well amyloid-β (Aβ) deposits transgenic mouse models. Our EMBER (excitation multiplexed bright emission recording) imaging...
Peripheral nerve injury (PNI) is a common and severe clinical disease worldwide, which leads to poor prognosis because of the complicated treatments high morbidity. Autologous grafting as gold standard still cannot meet needs transplantation its low availability limited size. The development artificial conduits was led novel direction for PNI treatment, while most currently developed lack biochemical cues promote regeneration. In this study, we designed composite neural conduit by inserting...
Dual carbon target is the definition of peak and neutrality, on one hand reducing fossil consumption in order to reduce emissions, other using afforestation increase absorption.In recent years, Sichuan ethnic areas actively implemented "double carbon" strategy, committed promoting low-carbon development agriculture.In this paper, agricultural emissions from 2006 2021 were measured, then efficiency was calculated by super-efficiency SBM model influencing factors Tobit model.The results show...
The design of organic–peptide hybrids has the potential to combine our vast knowledge protein with small molecule engineering create hybrid structures complex functions. Here, we describe computational a photoswitchable Ca 2+ -binding hybrid. designed molecule, designated switch (CaBS), combines an EF-hand motif from classical proteins such as calmodulin group that can be reversibly isomerized between spiropyran (SP) and merocyanine (MC) state in response different wavelengths light. MC/SP...
Here, using melamine as the main precursor and 6-(4-(fluoranthen-3-yl)phenyl)-1,3,5-triazine-2,4-diamine dopant, a 3-phenylfluoranthene-modified greenish-yellow-emitting g-C3N4 derivative was synthesized via thermal polymerization. Excited by blue light chips, high-performance white LEDs were fabricated red-emitting K2SiF6:Mn4+ phosphors.
The hydrophobic Aβ peptide is highly aggregation prone; it first forms soluble oligomers, which then convert into the amyloid fibrils found in cerebral plaques of Alzheimer's disease. It generally understood that as concentration increases, fibrillization process accelerated, but we examine limits on this phenomenon. We once a threshold exceeded, stable oligomer formed at expense fibril formation. suppression formation was observed by amyloid-binding dye Thioflavin T and solution nuclear...
Highly efficient fluorescence/phosphorescence hybrid WOLEDs have been realized by employing a new blue fluorescent material.
In this study, an "intelligent" graphitic carbon nitride nanosheets/ polyacrylamide/ polyacrylic acid (CNNS/ PAM/ PAA) composite hydrogel was prepared by radical polymerization method. The structure, swelling and fluorescent properties of the gels were investigated. results showed that mixed gel not only had pH sensitivity in aqueous solution, but also specific concentration-dependent intensities presence Ag+ over range (0–100) μM with a detection limit 6.31 μM. can be applied to...
High performance hybrid WOLEDs have been realized by precisely inserting ultrathin red/green phosphorescent layers in a blue exciplex emitter.
All fluorescent white organic light-emitting diodes (WOLEDs) have aroused significant interest owing to the advantages of excellent operational stability, low efficiency roll-off and cost.
The luminance degradation ratio and the corresponding relative change of exciton lifetimes for different hosts in resulting yellow PhOLEDs.
More than 90% of kidney cancers are attributed to renal cell carcinoma (RCC), which is however highly resistant traditional chemotherapy. The challenges met in treating RCC signify an imperative accelerate the development new and effective drugs. Preclinical testing has served as a foundation for evaluating potential effectiveness drugs, but this endeavor deeply restricted by current generation vitro two-dimensional culture models, cannot accurately mimic tumor microenvironment (TME)....