A5048858320- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- HIV/AIDS drug development and treatment
- Mycobacterium research and diagnosis
- Disaster Response and Management
- Tuberculosis Research and Epidemiology
- Global Security and Public Health
- Sustainable Development and Environmental Policy
- Hepatitis B Virus Studies
- Environmental and Social Impact Assessments
- HIV-related health complications and treatments
- Climate Change and Health Impacts
- Rabies epidemiology and control
- HIV, Drug Use, Sexual Risk
- Health and Conflict Studies
- HIV/AIDS oral health manifestations
- Peptidase Inhibition and Analysis
- Reproductive tract infections research
- Cardiac Fibrosis and Remodeling
- Data-Driven Disease Surveillance
- Zoonotic diseases and public health
- Clinical Laboratory Practices and Quality Control
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
Metabiota (United States)
2022-2023
Kativik Regional Government
2021
American College of Chest Physicians
2021
Roche (Switzerland)
2021
McGill University Health Centre
2021
Nunavik Regional Board of Health and Social Services
2021
University of Haiti
2014-2017
Centers for Disease Control and Prevention
2017
University of South Florida
2013
Instituto de Medicina Tropical “Pedro Kourí”
2007
Pediatric human immunodeficiency virus (HIV) infection remains an important public health issue in resource-limited settings. In 2015, 1.4 million children aged <15 years were estimated to be living with HIV (including 170,000 infants born 2015), the vast majority sub-Saharan Africa (1). 2014, 150,000 died from HIV-related causes worldwide (2). Access timely diagnosis and treatment for HIV-infected reduces HIV-associated mortality, which is approximately 50% by age 2 without (3). Since 2011,...
Introduction Viral load (VL) assessment is the preferred method for diagnosing and confirming virologic failure patients on antiretroviral therapy (ART). We conducted a retrospective cross-sectional study to evaluate suppression rate among ART ≥6 months in five hospitals around Port-au-Prince, Haiti. Methods Plasma VL was measured with <1,000 copies/mL were defined as virologically suppressed. A second test performed within at least six of first test. Factors associated analyzed using...
Abstract Natriuretic peptide receptor A (NPRA), the signaling for cardiac hormone, atrial natriuretic (ANP), is expressed abundantly in inflamed/injured tissues and tumors. NPRA deficiency substantially decreases tissue inflammation inhibits tumor growth. However, precise mechanism of function whether it links tumorigenesis remains unknown. Since both injury repair growth require stem cell recruitment angiogenesis, we examined role angiogenesis as a model this study. In vitro cultures,...
Herpes simplex virus type 2 (HSV-2), one the most common causes of genital ulcers, appears to increase both risk HIV acquisition and transmission. HSV-2/HIV co-infection among pregnant women may perinatal transmission HIV. This study describes rates HSV-2 in Haiti test performance this population. Unlinked residual serum specimens from 2012 National Syphilis Sentinel Surveillance Survey were tested using two commercial kits (Focus HerpeSelect, Kalon) for antibodies. We evaluated...
To evaluate an external quality assessment (EQA) program for human immunodeficiency virus (HIV) rapid diagnostics testing by the Haitian National Public Health Laboratory (French acronym: LNSP). Acceptable performance was defined as any proficiency (PT) score more than 80%.
Laboratory-enhanced surveillance is critical for rapidly detecting the potential re-emergence of Ebola virus disease. Rapid diagnostic tests (RDT) antigens could expand capacity disease.The Guinean National Coordination Response conducted a pilot implementation to determine feasibility broad screening patients and corpses with OraQuick® RDT.The team developed protocols trained healthcare workers screen in Forécariah prefecture, Guinea, from 15 October 30 November 2015. Data collected...
During initial expansion of HIV care and treatment services in Haiti, most laboratories relied on a manual method CD4 testing based
The main objective of this study was to determine the frequency and patterns HIV drug resistance-associated mutations among children under 18 months age born HIV-1-positive mothers enrolled in prevention mother-to-child transmission services Haiti.
Tungiasis is endemic in poverty-stricken communities of South and Central America, Africa, Asia, the Caribbean. This ectoparasitosis, caused by female sand flea Tunga penetrans, associated with considerable longterm morbidity severely affected patients, including toe deformation limited mobility. In Haiti, tungiasis poorly documented but known to occur. study first formal investigation Haiti.A total 383 patients four regions (Belle Fontaine, Vallue, Savanette, Cerca Carvajal) were examined...
Haiti's health system has faced many challenges over the years, with competing priorities in context of chronic financial and human resource limitations. As a result, existing notifiable disease surveillance was unable to provide most basic epidemiologic data for public decision-making action. In wake January 2010 earthquake, Haitian Ministry Public Health Population collaborated U.S. Centers Disease Control Prevention, Pan American Organization, other local international partners implement...
The Ebola virus disease (Ebola) epidemic in West Africa began Guinea early 2014. reemergence of and risk ongoing, undetected transmission continues because the potential for sexual other as yet unknown pathways. On March 17, 2016, two new cases were confirmed by World Health Organization. This is first since original outbreak country was declared over on December 29, 2015. prefecture Forécariah, western Guinea, considerably affected 2015, with an incidence rate 159 per 100,000 persons. also...
Since the 2010 earthquake, tuberculosis (TB) control has been a major priority for health sector response and recovery efforts in Haiti. The goal of this study was to analyze trends TB case notification Haiti from aggregate data reported by National Control Program understand effects such efforts. A total 95,745 patients were registered treatment between 2015. Three regions, West, Artibonite, North departments accounted 68% cases notified during period. Patients 15–34 age groups represented...
Before the 2010 devastating earthquake and cholera outbreak, Haiti's public health laboratory systems were weak services limited. There was no national strategic plan only minimal coordination across network. Laboratory capacity further weakened by destruction of over 25 laboratories testing sites at departmental peripheral levels loss life among health-care workers. However, since 2010, tremendous progress has been made in building stronger infrastructure training a qualified workforce...
HIV rapid diagnostic tests (RDTs) are instrumental in scaling-up testing services (HTS) low-income and middle-income countries (LMICs). misdiagnosis is a growing concern the era of expanded decentralised access to HTS. External quality assurance (EQA) programme including proficiency (PT) for RDTs priority guarantee accuracy reliability patients' result. Here we sharing Haiti's 11 years' experience implementing EQA help address some challenges faced by other LMICs. HTS expanding beyond...
<h3>Background:</h3> Active screening for tuberculosis (TB) involves systematic detection of previously undiagnosed TB disease or latent infection (LTBI). It may be an important step toward elimination among Inuit in Canada. We aimed to evaluate the cost-effectiveness community-wide active and 2 communities Nunavik. <h3>Methods:</h3> incorporated data from into a decision analysis model. predicted TB-related health outcomes over 20-year time frame, beginning 2019. assessed presence varying...
Over the last 15 years, prevalence of HIV in Haiti has stabilised to around 2.0%. However, key populations remain at higher risk contracting and other sexually transmitted infections (STIs). The is 12.9% among men having sex with (MSM). There limited information about STI Haitian population general even less populations. We assessed burden Chlamydia trachomatis (CT) Neisseria gonorrhoeae (NG) factors for MSM Haiti. A cross-sectional study was conducted. were recruited from seven health...
Study design and patient selectionWe performed a cross sectional study of patients with advanced HIV (CD4 cell counts <200 cells/mm 3 ) within health facilities providing care treatment across five the 10 administrative departments AbstractCryptococcal meningitis is common opportunistic infection among persons HIV-associated immunosuppression associated high mortality.The prevalence asymptomatic cryptococcal antigenemia (CrAg) can inform potential utility screening pre-emptive prevention...
Background: In low HIV prevalence settings, understanding the transmission dynamics and impact of drug resistance is critical to curb down epidemic. This study aims explore drug-resistance mutations (DRMs) among key populations in Haiti. Settings: Eligible participants (naive, treated) were selected from 7 population friendly health care centers Port-au-Prince, Haiti, September 2018 July 2019. Methods: A total 119 HIV-1 pol sequences analyzed men having sex with (MSM), female workers (FSWs),...
Bats are presumed reservoirs of diverse α- and β- coronaviruses (CoVs) understanding the diversity bat-CoVs role bats play in CoV transmission is highly relevant context current COVID pandemic. We sampled Côte d’Ivoire (2016-2018) living at ecotones between anthropogenic wild habitats Marahoué National Park, a recently encroached protected area, to detect characterize CoVs circulating humans. A total 314 were captured, mostly during rainy season (78%), RNA was detected three (0.96%)....