- Glioma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Spinal Dysraphism and Malformations
- Fetal and Pediatric Neurological Disorders
- Head and Neck Surgical Oncology
- Neurofibromatosis and Schwannoma Cases
- Pituitary Gland Disorders and Treatments
- Neurosurgical Procedures and Complications
- Neurological Disorders and Treatments
- Brain Metastases and Treatment
- Spinal Fractures and Fixation Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer, Hypoxia, and Metabolism
- History of Medical Practice
- Neuroblastoma Research and Treatments
- Nanoparticle-Based Drug Delivery
- Metabolism, Diabetes, and Cancer
- RNA Interference and Gene Delivery
- Adrenal and Paraganglionic Tumors
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
Iuliu Hațieganu University of Medicine and Pharmacy
2016-2025
Spitalul Clinic Județean de Urgență Cluj-Napoca
2014-2021
Clinical Emergency Hospital Bucharest
2011-2016
Emergency University
2014
Amita Health St. Mary's Hospital
2014
Technical University of Cluj-Napoca
2012
Abstract Background Due to the lack of high-quality evidence which has hindered development evidence-based guidelines, there is a need provide general guidance on cranioplasty (CP) following traumatic brain injury (TBI), as well identify areas ongoing uncertainty via consensus-based approach. Methods The international consensus meeting post-traumatic CP was held during International Conference Recent Advances in Neurotraumatology (ICRAN), Naples, Italy, June 2018. This endorsed by...
Intracranial epidermoid cysts are benign slow-growing ectodermal inclusions that account for less than 1% of all intracranial tumors. We retrospectively reviewed 36 such cases to evaluate the demographic characteristics, clinical manifestations, anatomical distribution, surgical management, and treatment outcome these Additionally, we sought identify relationship between median or paramedian cistern tumor localization parameters, as recurrence risk, hospitalization duration, postoperative...
Background In cerebrospinal fluid (CSF) leakage endoscopic repair, lumbar drains (LDs) were used in an attempt to increase success rates. To critically assess the relationship between use of LDs and recurrent leaks, we embarked on this randomized prospective study. Methods Patients undergoing CSF leak repair 2000 2012 into two groups: 75 patients managed without other group LD was always placed. Different parameters analyzed identify their with failures: occurrence increased intracranial...
Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to lack of clear guidance. This project aims create European document improve adherence and adapt local protocols based on available resources national health systems. After thorough non-systematic review, steering committee (SC) formed expert panel (EP) for two-round questionnaire using the Delphi method. The employed 9-point Likert scale assess...
Traumatic brain injury (TBI) is a leading cause of death and disability for which there currently no effective drug therapy available. Because drugs targeting single TBI pathological pathway have failed to show clinical efficacy date, pleiotropic agents with effects on multiple mechanisms secondary damage could represent an option improve recovery outcome in patients. In this multicenter retrospective study, we investigated severity-related safety the add-on two concentrations (20 ml/day or...
Glioblastoma multiforme (GBM) represents a very aggressive brain tumor. Angiogenesis is the formation of network new blood vessels, from preexisting ones. It plays an important role in tumor, as it supplies with oxygen
Neuroplasticity is a complex process of structural and functional reorganization brain tissue. In the fetal period, neuroplasticity plays an important role in emergence development white matter tracts. Here, we aimed to study architecture normal brains by way Klingler's dissection. Ten were collected from utero deceased fetuses aged between 13 35 gestational weeks (GW). During this observed modifications volume, shape, sulci configuration. Our findings indicate that major tracts follow four...
The updated definition of TIA emphasizes tissue characteristics rather than symptom duration, defining as a transient neurological episode without ischemic lesions on brain imaging, including DWI. If imaging reveals lesion, even in patients with symptoms, the event is reclassified minor stroke. This retrospective cross-sectional study aimed to determine period prevalence DWI diagnosis. Adults aged 18–90 years, diagnosed by neurologist, and who underwent MRI-DWI at CMT hospital within first...
The updated definition of a TIA emphasizes tissue characteristics rather than symptom duration, defining as transient neurological episode without ischemic lesions in brain imaging, including DWI. If imaging reveals lesion, even patients with symptoms, the event is reclassified minor stroke. This retrospective observational study aimed to determine prevalence DWI diagnosis. Adults aged 18-90 years, diagnosed by neurologist and who underwent MRI-DWI at CMT hospital within first week after...
Neural tube defects (NTDs) are a group of congenital malformations the central nervous system occurring at an average rate 1 per 1,000 human pregnancies worldwide. Numerous genetic and environmental factors discussed to be relevant in their etiology. In mice, mutants >200 genes including planar cell polarity (PCP) pathway known cause NTDs, recently, heterozygous mutations VANGL1 gene have been described small subset patients with NTDs. We performed mutation analysis 144 unrelated individuals...