Andreas K. Demetriades
A5062079553- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Infectious Diseases and Tuberculosis
- Trauma and Emergency Care Studies
- Cervical and Thoracic Myelopathy
- Musculoskeletal pain and rehabilitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Surgical Simulation and Training
- Spinal Dysraphism and Malformations
- History of Medical Practice
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Cardiac, Anesthesia and Surgical Outcomes
- Head and Neck Surgical Oncology
- Global Health and Surgery
- COVID-19 and healthcare impacts
- Pelvic and Acetabular Injuries
- Orthopedic Infections and Treatments
- Spinal Hematomas and Complications
- Diversity and Career in Medicine
- Spinal Cord Injury Research
- History of Medicine Studies
- Amoebic Infections and Treatments
- Traumatic Brain Injury Research
- Intracranial Aneurysms: Treatment and Complications
Leiden University Medical Center
2023-2025
Edinburgh Royal Infirmary
2020-2025
NHS Lothian
2019-2025
Royal Victoria Hospital
2025
University of Ulster
2025
Nottingham University Hospitals NHS Trust
2025
Spinal Research
2019-2024
Ospedale Santa Maria Goretti
2024
University of Edinburgh
2017-2024
Royal Edinburgh Hospital
2024
Objective: This study aims to assess global trends in the use of open surgery versus minimally invasive (MIS) for treatment single-level L4–5 degenerative lumbar spondylolisthesis (DLS).Methods: A cross-sectional online survey issued by AO Spine Knowledge Forum Degenerative was conducted among members between July and September 2023. Participants were presented with 3 clinical cases grade 1 DLS, each varying degrees stenosis instability. The captured surgeon demographics preferences MIS...
A prospective randomized study.To compare occupational radiation exposure to the surgeon, as well patient, during posterior lumbar spine instrumentation in 10 navigated cases (navigated) versus 11 using freehand technique (non-navigated).The use of navigation increases accuracy instrumentation.A further speculated benefit is reduction surgeon. However, this has so far not been evaluated such comparative manner.Radiation surgeon was measured by digital dosimeters placed at level eye, chest,...
Artificial Intelligence (AI) plays an integral role in enhancing the quality of surgical simulation, which is increasingly becoming a popular tool for enriching training experience surgeon. This spans spectrum from facilitating preoperative planning, to intraoperative visualisation and guidance, ultimately with aim improving patient safety. Although arguably still its early stages widespread clinical application, AI technology enables personal evaluation provides personalised feedback...
Literature Review (Narrative).To contextualize AO Spine RECODE-DCM research priority number 5: What is the socio-economic impact of DCM? (The financial living with DCM to individual, their supporters, and society as a whole).In this review, we introduce methodology health-economic investigation, including potential techniques approaches. We summarize current evidence within DCM, so far focused on surgical treatment. also cover first national estimate, in partnership Myelopathy.org from...
Spondylodiscitis is a potentially life-threatening infection of the intervertebral disk and adjacent vertebral bodies, with mortality rate 2-20%. Given aging population, increase in immunosuppression, intravenous drug use England, incidence spondylodiscitis postulated to be increasing; however, exact epidemiological trend England remains unknown.The Hospital Episode Statistics (HES) database contains details all secondary care admissions across NHS hospitals England. This study aimed HES...
OBJECTIVE It is unknown whether efforts to expand access neurosurgery worldwide have translated an increase in the global workforce, particularly low- and middle-income countries. The main objective of this study was quantify number distribution consultant neurosurgeons worldwide, while also identifying temporal geographic trends workforce different income levels WHO regions, analyzing what factors might contribute growth a national workforce. METHODS This subanalysis electronic...
Abstract Background The early management of polytrauma patients with traumatic spinal cord injury (tSCI) is a major challenge. Sparse data available to provide optimal care in this scenario and worldwide variability clinical practice has been documented recent studies. Methods A multidisciplinary consensus panel physicians selected for their established scientific expertise the acute tSCI different specializations was established. World Society Emergency Surgery (WSES) European Association...
Abstract Background The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates disease burden in EU individual 27 countries 2019, compares them with those 2010. Methods We used Global Disease 2019 study 95% uncertainty intervals whole each country to evaluate age-standardised death, years life lost (YLLs), lived disability (YLDs) disability-adjusted (DALYs)...
Knowledge translation from research to clinical practice can often be challenging, and modification patterns among surgeons may stem a variety of sources, including personal experience, peer influence, ongoing education, evolving findings. This study aimed investigate the adoption amongst for newer innovations analyse factors affecting implementation same in practice. We used osteobiologics as case example. An international expert survey was conducted AO Spine users members. The survey,...
Only a handful of cases de-novo malignancies the vestibulocochlear nerve have been reported. Even rarer is malignant transformation previously histologically diagnosed benign vestibular schwannoma. We present case young adult who had combined operative/Gamma knife treatment for schwannoma, followed by further surgery 2 years later. He represented 10 after original diagnosis with facial numbness and ataxia, MRI showing gross tumor recurrence. After radical resection, histology showed to...
AbstractWe report the use of three-dimensional or 3D printed, patient-specific anatomy as a tool to improve informed patient consent and understanding in case posterior lumbar fixation. Next, we discuss its utility an educational enhance imaging interpretation by neurosurgery trainees.Keywords:: printingmedical educationpatient AcknowledgementsWe thank Dr Zoe Morris for preparing anonymized CT DICOM files, Steve Gourlay at University Edinburgh School Engineering overseeing printing...
There are no guidelines for the management of brain abscesses in children, and there is a paucity recent data describing clinical microbiologic features. We aimed to identify factors affecting outcome inform antibiotic recommendations.From 1999 2009, 118 children presented with 4 neurosurgical centers United Kingdom. Clinical, treatment were collected.The commonest preceding infection was sinusitis, 59% all receiving antibiotics before diagnosis. Nonspecific symptoms common, only 13% having...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or Covid-19), which began as an epidemic in China and spread globally a pandemic, has necessitated resource management to meet emergency needs of Covid-19 patients other emergent cases. We have conducted survey analyze caseload measures adapt indications for perception crisis.We constructed questionnaire snapshot neurosurgical activity, resources, during 1 week with usual activity December 2019 SARS-CoV-2 pandemic March 2020. The...
Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack standardised clinical definitions outcome measures. This prospective multi-centre observational cohort study adults with UK. We assessed presentation, investigation, management, all Core Outcome Set domains up one year post-operatively using clinician participant reporting....
Pyogenic spondylodiscitis presents significant diagnostic and therapeutic challenges. In Germany, a comprehensive understanding of its epidemiology inpatient management outcomes is limited, hindering the optimisation strategies. This study aimed to characterise evolving epidemiological trends pyogenic in concurrently evaluate strategies outcomes. We performed retrospective population-based cases Germany from 2005 2021, utilising data German Federal Statistical Office database. The parameters...
The majority of patients presenting with suspected clinical cauda equina syndrome (CES) have no identifiable structural cause for their symptoms ('scan-negative' CES). Understanding these aids differentiation and management in CES.A retrospective electronic note review was undertaken CES, defined as ≥ 1 acute bladder, bowel, sexual dysfunction or saddle numbness, to a regional neurosciences centre. We investigated radiology, features, psychiatric functional disorder comorbidities outcome...
Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress time constraints, sometimes with no awareness of the trauma's causes or patient's personal clinical information. In this perspective, dynamics how trauma function is fundamental ensuring best performance outcomes.An online survey was conducted among World Society Surgery members in early 2021. 402 fully filled questionnaires on topics knowledge translation tools,...
Abstract Background Work-related musculoskeletal disorders (WMSDs) affect a significant percentage of the neurosurgical workforce. The aim current questionnaire-based study was to examine prevalence WMSDs amongst neurosurgeons, identify risk factors, and views neurosurgeons regarding ergonomics. Methods From June August 2020, members “European Association Neurosurgical Societies,” “ Neurosurgery Research Listserv , ” “Latin American Federation Societies” were asked complete an electronic...