A5032561038- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Cell Adhesion Molecules Research
- Diversity and Career in Medicine
- History of Medical Practice
- Blood Coagulation and Thrombosis Mechanisms
- Protease and Inhibitor Mechanisms
- Cerebrospinal fluid and hydrocephalus
- Surgical Simulation and Training
- Spinal Fractures and Fixation Techniques
- Acute Ischemic Stroke Management
- Occupational Therapy Practice and Research
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Pituitary Gland Disorders and Treatments
- Cervical and Thoracic Myelopathy
- Head and Neck Surgical Oncology
- Healthcare professionals’ stress and burnout
- Traumatic Brain Injury Research
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Spine and Intervertebral Disc Pathology
- COVID-19 Clinical Research Studies
- Spinal Hematomas and Complications
University Hospital of Larissa
2016-2025
University of Illinois Urbana-Champaign
2001-2025
Illinois College
2001-2025
Peoria campus of the University of Illinois System
2001-2025
University of Thessaly
2008-2024
NHS Lothian
2024
Western General Hospital
2024
National and Kapodistrian University of Athens
2002-2003
University of Illinois Chicago
2001
The University of Texas MD Anderson Cancer Center
2000-2001
Studies on head injury-induced pituitary dysfunction are limited in number and conflicting results have been reported.To further clarify this issue, 29 consecutive patients (24 males), with severe (n = 21) or moderate 8) trauma, having a mean age of 37 ± 17 years were investigated the immediate post-trauma period.All required mechanical ventilatory support for 8-55 days enrolled study within few before ICU discharge.Basal hormonal assessment included measurement cortisol, corticotropin, free...
Abstract Background Due to the lack of high-quality evidence which has hindered development evidence-based guidelines, there is a need provide general guidance on cranioplasty (CP) following traumatic brain injury (TBI), as well identify areas ongoing uncertainty via consensus-based approach. Methods The international consensus meeting post-traumatic CP was held during International Conference Recent Advances in Neurotraumatology (ICRAN), Naples, Italy, June 2018. This endorsed by...
Object Cerebral vasospasm is a common and potentially devastating complication of aneurysmal subarachnoid hemorrhage (aSAH). Inflammatory processes seem to play major role in the pathogenesis vasospasm. The Creactive protein (CRP) constitutes highly sensitive inflammatory marker. association elevated systemic CRP coronary has been well established. Additionally, elevation serum levels demonstrated patients with aSAH. purpose current study was evaluate possible relationship between CSF...
To assess the prevalence and outcome of external cerebral ventricular drainage-associated ventriculitis in neurocritical patients before after implementation a bundle control measures.Clinical prospective case series.University Hospital Larissa, Greece.Consecutive were recruited from ICU hospital. Patient inclusion criteria included presence drainage stay more than 48 hours.The measures 1) reeducation personnel on issues infection related to drainage, 2) meticulous intraventricular catheter...
Object In addition to difficulties with anesthetic and medical management, transsphenoidal operations in patients longstanding acromegaly are associated inherent intraoperative challenges because of anatomical variations that occur frequently these patients. The object this study was review the overall safety profile anatomical/technical surgery acromegaly. Methods authors performed a retrospective analysis 169 who underwent endoscopic for growth hormone–secreting adenomas assess incidence...
To investigate the association of (variable number tandem repeat) interleukin (IL) 1RN and (-511) IL-1B gene polymorphisms with brain hemorrhagic events after traumatic injury (TBI).Data from CT, Glasgow Coma Scale (GCS) at admission, 6-month Outcome (GOS) modified Rankin (mRS) were collected for 151 prospectively recruited patients TBI. IL-1RN genotypes determined using standard methods. Presence vs absence any type hemorrhage was main outcome. Type hemorrhage, GCS GOS mRS secondary...
Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to lack of clear guidance. This project aims create European document improve adherence and adapt local protocols based on available resources national health systems. After thorough non-systematic review, steering committee (SC) formed expert panel (EP) for two-round questionnaire using the Delphi method. The employed 9-point Likert scale assess...
Human tissue factor pathway inhibitor-2 (TFPI-2) is a 32-kDa serine protease inhibitor that inhibits plasmin, trypsin, chymotrypsin, cathepsin G, and plasma kallikrein but not urokinase tissue-type plasminogen activators or thrombin. After discovering TFPI-2 expression down-regulated lost during tumor progression, we investigated the role of in invasiveness prostate cancer cell line (LNCaP). We stably transfected LNCaP cells with 0.7-kb vector expressing sense orientation measured protein...
Cranioplasty has been considered for several decades as a protective and cosmetic procedure. It recently postulated that cranioplasty may have therapeutic role, improve the patient's functional outcome after decompressive craniectomy (DC). The appropriate timing remains unknown. In our current study, we review literature evaluating relationship of its complication rate outcome. PubMed database was searched to identify any relevant articles. following terms were used keywords: "cranioplasty",...
To prospectively explore the incidence and risk factors for postoperative delirium in elderly patients following lumbar spine surgery.This prospective study enrolled 148 consecutive over age of 65 who were scheduled to undergo surgery. Patients screened using short Confusion Assessment Method (CAM) postoperatively. Patient demographics relevant medical information collected. Logistic regression analysis was used identify associated with delirium.Eighty-three (56.1%) underwent surgery (not...
INTRODUCTION: Neurosurgeons may resort to caffeine, alcohol, and various drugs maintain peak performance as they grapple with work demands escalated stress. METHODS: An anonymous survey of 23 questions formulated by our research group was distributed through personal contacts neurosurgical societies. Inquiries revolved around the use medications other substances for job-related reasons. Data were analyzed via regression descriptive statistics in python. RESULTS: In total, 215 neurosurgeons...
Degradation of the extracellular matrix is a prerequisite for invasive phenotype in glioma cells. Several proteases released by invading tumor cells seem to participate focal degradation proteins. Using enzymatic assays, Western blotting, and Northern blotting techniques, we investigated whether cathepsin B level was associated with malignant grade seven human cell lines. Cathepsin activity protein content levels were higher glioblastoma lines than anaplastic astrocytoma or low-grade...