A5017850999- Intraperitoneal and Appendiceal Malignancies
- Ovarian cancer diagnosis and treatment
- Growth Hormone and Insulin-like Growth Factors
- Renal cell carcinoma treatment
- Inflammatory Bowel Disease
- Pediatric Urology and Nephrology Studies
- Sexual Differentiation and Disorders
- Adrenal Hormones and Disorders
- Appendicitis Diagnosis and Management
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Pharmacological Effects and Assays
- Diabetes and associated disorders
- Acute Lymphoblastic Leukemia research
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Forensic Anthropology and Bioarchaeology Studies
- Cardiovascular Conditions and Treatments
- Thermal Expansion and Ionic Conductivity
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Pituitary Gland Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Hip disorders and treatments
- Health and Lifestyle Studies
The Netherlands Cancer Institute
2021-2025
Oncode Institute
2024
OLVG
2020
Lund University
1970-1996
New York College of Podiatric Medicine
1996
County Hospital
1991
Halmstad University
1990
The spontaneous growth process in Turner's syndrome is characterized by a progressive decline height velocity during childhood and no pubertal spurt. Therefore, therapy aimed at improving as well increasing final desirable for most girls with syndrome. Forty-five syndrome, 9-16 yr of age (mean age, 12.2 yr), were allocated to three study groups. Group 1 (n = 13) was initially treated oxandrolone alone; after treatment, GH without (group 1a; n 6) or 1b; 7) ethinyl estradiol added. 2 17) plus...
While immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, their efficacy in high-grade serous ovarian (HGSOC) remains limited. Some patients, however, achieve lasting responses, emphasizing the need to understand how tumor microenvironment and molecular characteristics influence ICI response. The phase 2 Neo-Pembro study (NCT03126812) included 33 untreated stage IV HGSOC who were scheduled for 6 cycles of carboplatin-paclitaxel interval cytoreductive surgery....
Growth, weight gain, and human growth hormone secretion were studied for 3 to 7 years in 27 children with acute leukemia complete continuous remission. Growth gain matched sex age by calculating the standard deviation score. The mean SD score height velocity was subnormal during three of therapy. A catch up occurred first year after cessation loss final attained small. HGH at end therapy yearly intervals thereafter two provocative tests; glucagon sleep. No significant difference seen between...
Growth rate was measured in 12 children with Crohn's disease and growth retardation, using roentgen stereophotogrammetric analysis. The method chosen as it provides an opportunity to record accurately during short periods of time. followed at variable intervals 4–12 weeks depending on the clinical situation. shown correlate symptoms, laboratory tests nitrogen balance. These findings indicate that growth, when is affected, fluctuates a similar way albumin, acute phase proteins all assumed...
ABSTRACT. Roentgen stereophotogrammetry is a new method for short term analysis of growth rate. Growth measured over the zone in distal fibula and fraction total statural growth. Normal rate about 15 μm/day at 5 cm/year. The was used to follow six months before after surgery retarded children with Crohn's disease. increased significantly ( p <0.01) within three from 5.8 operation 15.8 postoperatively had reached 18.0 μm/day. Improved could be recorded as early four weeks operation....
(Abstracted from Lancet Oncol 2023;24:P1109–P1118) Although the 5-year survival of patients with advanced ovarian cancer has improved, overall at 10 years remains approximately 13%. Hyperthermic intraperitoneal chemotherapy (HIPEC) involves delivery chemotherapeutic agents directly into peritoneum in combination hyperthermia, which enhances penetration and increases sensitivity to platinum compounds by inducing a transient state homologous recombination deficiency.
<h3>Introduction/Background</h3> In March 2019, interval cytoreductive surgery (ICS) with hyperthermic intraperitoneal chemotherapy (HIPEC) became the standard of care for FIGO stage III ovarian cancer patients treated neo-adjuvant in Netherlands. The OVHIPEC-1 trial showed a bowel resection rate 23% both arms, significant difference stoma formation among undergoing (43% non-HIPEC arm and 72% HIPEC arm). As there is no evidence that associated higher anastomotic leakage rate, surgeon's...