A5015522560- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Cerebrospinal fluid and hydrocephalus
- Spinal Hematomas and Complications
- Bone fractures and treatments
- Cervical and Thoracic Myelopathy
- Neurosurgical Procedures and Complications
- Orthopaedic implants and arthroplasty
Princess Alexandra Hospital
2025
University of Washington
2021-2024
Neurological Surgery
2021-2024
PURPOSE This study evaluated DB-020, a formulation of thiosulfate for intratympanic (IT) injection, in patients receiving high-dose cisplatin chemotherapy. METHODS randomized phase Ib clinical trial enrolled older than 18 years from five centers Australia and the United States scheduled at least three cycles total cumulative exposure ≥280 mg/m 2 . Patients received IT DB-020 (at dose level either 12% or 25%) one ear placebo other, once every 3 4 weeks, within hours before cisplatin. The...
OBJECTIVE Recombinant human bone morphogenetic protein–2 (rhBMP-2) is used in spinal arthrodesis procedures to enhance bony fusion. Research has suggested that it the most cost-effective fusion enhancer, but there are significant upfront costs for healthcare system. The primary objective of this study was determine whether intraoperative dosing and corresponding changed with surgeon cost awareness. secondary describe surgical complications before after awareness rhBMP-2 cost. METHODS A...
This study evaluated frontal behavioural symptoms, via the FrSBe self-report, in military personnel with and without a history of blast-related mild traumatic brain injury (mild TBI).
OBJECTIVE Anterior cervical discectomy and fusion (ACDF) is the most common treatment for degenerative disease of spine. Given high rate pseudarthrosis in multilevel stand-alone ACDF, there a need to explore utility novel grafting materials. In this study, authors present single-institution retrospective study patients with spine who underwent ACDF surgery or without cellular allograft supplementation. METHODS prospectively collected database, 28 supplemented (ViviGen) 25 decellularized...