A5070029938- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Acne and Rosacea Treatments and Effects
- Dermatologic Treatments and Research
- Nail Diseases and Treatments
- Cutaneous Melanoma Detection and Management
- Oral Health Pathology and Treatment
- Cultural and Sociopolitical Studies
- melanin and skin pigmentation
- Ocular Diseases and Behçet’s Syndrome
- Drug-Induced Adverse Reactions
- Dermatological and COVID-19 studies
- Cutaneous lymphoproliferative disorders research
- Cancer and Skin Lesions
- Skin Protection and Aging
- Genetic and rare skin diseases.
- Genital Health and Disease
- Hair Growth and Disorders
- Rheumatoid Arthritis Research and Therapies
- Facial Rejuvenation and Surgery Techniques
- Allergic Rhinitis and Sensitization
- Chemotherapy-related skin toxicity
- Ovarian function and disorders
Memorial Ankara Hospital
2017-2025
Sağlık Bilimleri Üniversitesi
2017-2025
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2016-2025
Ministry of Health
2016-2025
National Institutes of Health
2025
National Cancer Institute
2025
Izmir University
2025
University of Health Sciences
2017
Psychiatric Association of Turkey
2017
University of Health Sciences Antigua
2017
Generalized pustular psoriasis (GPP) is a rare and severe inflammatory disease characterized by widespread superficial sterile pustules on an erythematous background.This multicentre study aimed to determine the clinical profile course in large cohort of patients with GPP.One hundred fifty-six GPP (mean age, 44.2 ± 18.7 years) who met diagnostic criteria European Consensus Report were included study. Sociodemographic characteristics, quality life, triggering factors disease, clinical,...
COVID-19 pandemic has a significant impact on public health, whether directly or indirectly. The first case was seen in Turkey March 11, and the World Health Organization (WHO) declared 12, 2020. study aimed to document effect of dermatology outpatient clinics Turkey. Fifteen tertiary hospitals from 13 provinces were included study, which conducted between January 12 May International Codes Diseases (ICD-10) categories patients' characteristics evaluated before after pandemic. A total 164...
Approximately 50% of prostate cancer (PCa) patients harbor fusions involving the TMPRSS2 and ERG genes. Despite this, tailored therapies targeting fused gene, tERG, remain undeveloped. Our study analyzed biopsy samples from two clinical trials assessing efficacies androgen receptor (AR) signaling inhibitors (ARSIs). The results revealed that tERG promotes resistance to ARSIs is associated with elevated levels glucocorticoid (GR). Subsequent assays showed GR directly interacts alleviates...
Introduction: An emerging hypothesis suggests a potential link between enhanced intestinal permeability and the advancement of chronic spontaneous urticaria (CSU). Objective: This study aimed to investigate role in etiopathogenesis CSU by measuring serum zonulin levels, marker permeability, both patients control subjects. Additionally, sought explore correlation severity illness levels. Methods: The involved 61 with 59 healthy individuals. For patients, comprehensive data was collected,...
Several rare subtypes of melanoma, beyond the classic variants, have been described in literature. The rarity these variants can hinder recognition and lead to delays clinical diagnosis. Bullous melanoma is one such subtype. Blister formation bullous occur either intraepidermally or subepidermally. While most reported cases exhibit intraepidermal separation, only three with subepidermal separation documented date. Here, we present a case characterized by exceptional recurrent episodes.
Lymphomatoid papulosis (LyP) is a rare, chronic CD30+ cutaneous lymphoproliferative disorder characterized by recurrent, self-healing papulonodular lesions. Despite its benign clinical course, LyP histologically resembles malignant lymphomas, necessitating careful differentiation. A 42-year-old woman presented with 3-year history of recurring ulcerated lesions on her index finger. Histopathological examination revealed atypical lymphoid proliferation, confirming type A. Immunohistochemical...
401 Background: Patients diagnosed with localized high-risk PC have higher rates of recurrence, and neoadjuvant intensive hormonal therapies seek to treat occult micrometastatic disease by addition definitive treatment. We completed a phase 2 trial androgen deprivation therapy (ADT) plus the receptor (AR) inhibitor enzalutamide (enza) for 6 months prior radical prostatectomy (RP), in which 22 out 37 patients exhibited poor pathologic responses (NCT02430480). In current study, we aimed...
SUMMARY OBJECTIVE: In some diseases associated with inflammation, the C-reactive protein-to-albumin ratio can be used as a biomarker of inflammation. Since lichen planus is chronic inflammatory disease, our study aimed to investigate relationship between and disease activity whether it plays role in determining prognosis, compare them those subjects without planus. METHODS: This case–control study. Demographic data, clinical features, laboratory measures, including neutrophil, lymphocyte,...
ABSTRACT Biologic therapies targeting interleukin (IL)‐17 and IL‐23 have transformed psoriasis treatment, yet real‐world evidence on the impact of age treatment responses drug survival is limited. This study aims to compare early (12/16 weeks), mid term (24 weeks) long (52 Psoriasis Area Severity Index (PASI) in patients aged < 65 versus ≥ years receiving IL‐17 or inhibitors. In this retrospective study, 121 with moderate‐to‐severe plaque treated secukinumab, ixekizumab, guselkumab,...
Background: Truncal acne is often overlooked, although it as common facial acne. Objectives: We aimed to investigate the prevalence of truncal in patients with mild, moderate, and severe evaluate characteristics Methods: Patients aged ≥ 12 years who were diagnosed vulgaris at our dermatology outpatient clinics between May 2023 October categorized into two groups based on severity Results: Of patients, 69.9% (n = 381) female 30.1% 164) male. The mean age was 21.0 ± 5.1 years. upper back,...
Psoriasis is a chronic inflammatory skin disease in which lesions display angiogenesis and increased vascularity.The long-pulsed 1,064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser treats vascular suggests that it might also be used to treat nail psoriasis.Sixteen patients (10 males 6 females) with isolated psoriasis or only mild cutaneous involvement were enrolled the study. Nails treated for 3 sessions Nd:YAG once monthly. During course of treatment, bed matrix Nail Severity Index...
Immunosuppressive therapy has been a great concern during the pandemic. This study aimed to evaluate pandemic's impact on psoriasis patients treated with immunosuppressive drugs.The multicenter was conducted in 14 tertiary dermatology centers. Demographic data, treatment status, disease course, and cases of COVID-19 were evaluated using treatment.Of 1827 included, drug adherence rate 68.2%. Those receiving anti-interleukin (anti-IL) drugs more likely continue than conventional (OR = 1.50,...
Palmoplantar pustulosis (PPP) is a rare, chronic, inflammatory skin disease characterized by sterile pustules on palmar or plantar areas. Data PPP are scarce.To investigate the clinical characteristics and risk factors for severity in large cohort of Turkish patients with PPP.We conducted cross-sectional, multicentre study recruited from 21 tertiary centres across Turkey.In total, 263 (165 women, 98 men) were evaluated. Most (75.6%) former current smokers. The mean Pustulosis Area Severity...
Internalized stigma, adoption of negative attitudes and stereotypes the society regarding persons' illness, has not been studied previously in pediatric psoriasis patients.We aimed to investigate internalized stigma patients determine differences according factors affecting compared adult patients.This multicenter, cross-sectional, comparative study included 125 (55 female, 70 male; mean age±standard deviation [SD], 14.59±2.87 years) 1,235 (577 658 age±SD, 43.3±13.7 years). Psoriasis Stigma...
Introduction: CRP/albümin ratio (CAR) has been lately demonstrated as a prognostic factor and an indicator of disease activity, severity prognosis in solid organ malignancies inflammatory diseases. However, the effects CAR have not investigated mycosis fungoides (MF) patients yet. This study aimed to determine potential role diagnostic MF. Methods:We retrospectively electronic medical records 97 with MF admitted Dermatology Clinic Ankara Diskapi Yildirim Beyazit Training Research Hospital...
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Rosacea, a chronic inflammatory disease primarily affecting the central area of face, is complex condition whose mechanisms are still not fully understood. However, research has indicated positive correlation between two molecules: hypoxia-inducible factor-1α (HIF-1α) and interleukin-6 (IL-6). The levels HIF-1α in rosacea patients have yet to be assessed.