A5056756912- Immune cells in cancer
- Immune Cell Function and Interaction
- Macrophage Migration Inhibitory Factor
- Vagus Nerve Stimulation Research
- Gut microbiota and health
- Immune Response and Inflammation
- Antimicrobial Peptides and Activities
- Immunotherapy and Immune Responses
- Biomarkers in Disease Mechanisms
- Nuclear Receptors and Signaling
- Tryptophan and brain disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Diabetes and associated disorders
- Enhanced Recovery After Surgery
- Reproductive System and Pregnancy
- Olfactory and Sensory Function Studies
- Ion Channels and Receptors
- Phagocytosis and Immune Regulation
- Health and Medical Education
- Regulation of Appetite and Obesity
- Neonatal Respiratory Health Research
- Pediatric Pain Management Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Nicotinic Acetylcholine Receptors Study
- Dietary Effects on Health
Universidad Autónoma del Estado de Hidalgo
2023
Centro de Investigación en Materiales Avanzados
2020-2022
Instituto Politécnico Nacional
2015-2018
Center for Research and Advanced Studies of the National Polytechnic Institute
2011-2018
KU Leuven
2017-2018
Abstract Macrophages (Mφ) can be differentiated and polarized in vitro from human CD14+ monocytes under the influence of GM-CSF (GM-Mφ) M-CSF (M-Mφ). GM-Mφs are proinflammatory M-Mφs have an anti-inflammatory phenotype. We found selective expression lectin C-type domain family 5 member A (CLEC5A) transcripts scavenger receptor CD163 molecule-like 1 (CD163L1) by microarray assay. In vitro, CD163L1 was induced IL-10 CLEC5A inflammatory cytokines cell adherence. secondary lymphoid organs, their...
Objectives Vagus nerve stimulation (VNS), most likely via enteric neurons, prevents postoperative ileus (POI) by reducing activation of alpha7 nicotinic receptor (α7nAChR) positive muscularis macrophages (mMφ) and dampening surgery-induced intestinal inflammation. Here, we evaluated if 5-HT4 (5-HT4R) agonist prucalopride can mimic this effect in mice human. Design Using Ca 2+ imaging, the electrical field (EFS) was situ on mMφ evoked ATP jejunal tissue. Next, preoperative administration (1–5...
The ability of Mycobacterium tuberculosis (Mtb) to persist in its human host relies on numerous immune evasion strategies, such as the deregulation lipid metabolism leading formation foamy macrophages (FM). Yet specific factors phenotype Mtb-infected remain unknown. Herein, we aimed address whether cytokines contribute FM context Mtb infection. Our approach is based use an acellular fraction tuberculous pleural effusions (TB-PE) a physiological source local released during We found that...
Abstract Human CD14++CD16− and CD14+/loCD16+ monocyte subsets comprise 85 15% of blood monocytes, respectively, are thought to represent distinct stages in the differentiation pathway. However, fates both along macrophage (Mϕ) lineage have not yet been elucidated. We now evaluated potential CD14++ CD16− CD16+ monocytes differentiate be primed toward pro- or anti-inflammatory Mϕs upon culture with GM-CSF M-CSF, respectively (subsequently referred as GM14, M14, GM16, M16). Whereas GM16 GM14...
ABSTRACT Two major subsets of human Mo are identified based on CD14 and CD16 expression: the classical CD16– minor CD14+CD16+ Mo. In vitro studies suggested distinct function differentiation potential for each cell population. However, in vivo relevance these findings remains unclear. To evaluate development an model, we transferred both subpopulations into peritoneum immunocompromised mice homeostatic or inflammatory conditions. Inflammation was induced with soluble LPS particulate zymosan....
Circulating monocytes (Mo) play an essential role in the host immune response to chronic infections. We previously demonstrated that CD16(pos) Mo were expanded TB (tuberculosis) patients, correlated with disease severity and refractory dendritic cell differentiation. In present study, we investigated whether human subsets (CD16(neg) CD16(pos)) differed their ability influence early inflammatory against Mycobacterium tuberculosis. first evaluated capacity of migrate engage a microbicidal...
Obesity is a chronic inflammatory disease associated with adipose tissue macrophage (ATM) activation. ATMs from lean mice contribute to homeostasis by their M2-oriented polarization, whereas obesity leads an increase of M1 that underlies obesity-related metabolic disorders. In humans, studies characterizing and functional status are limited. Here we investigated ATM phenotype in visceral (VAT) subcutaneous (SAT) healthy obese individuals using two molecules previously identified as markers...
En respuesta a la importancia curricular de investigación en Licenciatura Enfermería y creciente participación los alumnos generación productos alto impacto, se ha organizado este mapa conceptual aspectos más destacados dentro del proceso Basada Evidencia (EBE). El método científico incorpora las cinco etapas EBE, quedando como eje pregunta PICO. es continuo, ya que evaluación mismo conlleva formulación preguntas clínicas. Dado población con problemas salud escasez personal enfermería...
Inflammation is a common factor in all pathologies, except normal pregnancy which not disease. The inflammation concept associated to immune system has been complemented by cells and inner secreted molecules interaction as coagulation tissue regeneration process, complex cross-talk integrated. Inflammatory response must be limited, it only proinflammatory mediators’ production stops disappears, anti-inflammatory release involved too. Unresolved inflammatory process participates early steps...