A5100402845- Carbon dioxide utilization in catalysis
- Advanced Polymer Synthesis and Characterization
- Lipid Membrane Structure and Behavior
- Chemical Synthesis and Analysis
- Force Microscopy Techniques and Applications
- Fluorine in Organic Chemistry
- Asymmetric Synthesis and Catalysis
- Antimicrobial Peptides and Activities
- Synthesis and Biological Evaluation
- Fuel Cells and Related Materials
- Synthesis and biological activity
- Mechanical and Optical Resonators
- CO2 Reduction Techniques and Catalysts
- Organometallic Complex Synthesis and Catalysis
- Histone Deacetylase Inhibitors Research
- Neurogenesis and neuroplasticity mechanisms
- Asymmetric Hydrogenation and Catalysis
- Supramolecular Self-Assembly in Materials
- Oxidative Organic Chemistry Reactions
- Polymer crystallization and properties
- Anaerobic Digestion and Biogas Production
- Epoxy Resin Curing Processes
- Carbon Dioxide Capture Technologies
- Environmental Toxicology and Ecotoxicology
- Polymer Science and PVC
Shaanxi Normal University
2003-2025
Tongji University
2012-2024
Guangdong Provincial People's Hospital
2024
Jinan University
2006-2024
East China Normal University
2012-2024
Henan University
2024
University of Manchester
2014-2023
Baotou Medical College
2023
Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine
2023
Zhangqiu City People's Hospital
2023
“Side-chain-type” and crosslinkable quaternized polypropylene was prepared by heterogeneous Ziegler–Natta catalyst mediated polymerization for use in highly stable anion exchange membranes.
This study demonstrates the dependence of non-local susceptibility effects on object orientation in gradient echo MRI and reduction by deconvolution using quantitative mapping. Imaging experiments were performed a 3T system spoiled 3D multi-echo GRE sequence phantoms known susceptibilities, human brains healthy subjects patients with intracerebral hemorrhages. Magnetic field measurements determined from multiple phase data. To determine mapping, these deconvolved through dipole inversion...
Abstract A series of tubular molecules with different lengths have been synthesized by attaching Trp‐incorporated peptides to the pillar[5]arene backbone. The are able insert into lipid bilayer form unimolecular transmembrane channels. One channels has revealed specifically Gram‐positive bacteria. In contrast, this channel cannot membranes mammalian rat erythrocytes even at high concentration 100 μ m . It was further demonstrated that, as a result membrane selectivity, exhibits efficient...
In this study, the effect of nine types biochar generated from three different feedstocks on anaerobic digestion (AD) sewage sludge was investigated. The obtained results indicated that methane production could be significantly enhanced by all used in test. maximum cumulative yield 218.45 L per kg VS for culture with corn straws pyrolyzed at 600 °C which also exhibited largest specific surface area. Adding an appropriate amount beneficial to improve yield, while excessive addition inhibit AD...
Molecular knots and entanglements form randomly spontaneously in both biological synthetic polymer chains. It is known that macroscopic materials, such as ropes, are substantially weakened by the presence of knots, but until now it has been unclear whether similar behaviour occurs on a molecular level. Here we show well-defined overhand knot chain increases rate scission under tension (≥2.6× faster) solution, because deformation backbone induced tightening activates otherwise unreactive...
The rational design of α-helix-mimicking peptidomimetics provides a streamlined approach to discover potent inhibitors for protein-protein interactions (PPIs). However, designing cell-penetrating long peptidomimetic scaffolds equipped with various functional groups necessary interacting large protein-binding interfaces remains challenging. This is particularly true targeting β-catenin/BCL9 PPIs. Here we designed series unprecedented helical sulfono-γ-AApeptides that mimic the binding mode...
We have investigated the mechanical dissociation of an ammonium/crown ether rotaxane using experimental (sonication) and computational (CoGEF) methods found that it breaks faster than its noninterlocked or uncoupled interlocked (i.e., pulled from both sides axle) counterparts. This was confirmed by analysis fragments, which are results a selective unstoppering reaction. Interestingly, initial also triggered elimination axle segment separating stopper ammonium binding station. CoGEF...
Abstract Neural progenitor cell (NPC) migration is an essential process for brain development, adult neurogenesis, and neuroregeneration after injury. Stromal cell-derived factor-1 (SDF-1, CXCL12) its traditional receptor CXCR4 are well known to regulate NPC migration. However, the discovery of CXCR7, a newly identified CXCL12 receptor, adds dynamics existing CXCL12/CXCR4 pair. Antagonists either or CXCR7 blocked CXCL12-mediated in transwell chemotaxis assay, suggesting that both receptors...
Mechanophores (mechanoresponsive molecules) offer great promises for the development of smart force-responsive materials. The activity a mechanophore can be tuned by altering its structure or composition actuating polymer. Here we show that [2]catenane act as mechanical protecting group diverting tensional forces away from mechanically active functional embedded in one rings. This property emerges mobility two rings catenane, which are able to rotate along each other until tension equalizes...
Abstract With the increase of human activities, cadmium (Cd) pollution has become a global environmental problem affecting biological metabolism in ecosystem. Cd very long half-life humans and is excreted slowly organs, which poses serious threat to health. In order better understand toxicity effects cadmium, third instar larvae Drosophila melanogaster (Canton-S strain) were exposed different concentrations (1.125 mg/kg, 2.25 4.5 9 mg/kg) cadmium. Trypan blue staining showed that intestinal...
We repeat the earliest claimed [2]catenane synthesis, reported by Wasserman over 60 years ago, in order to ascertain whether or not a nontemplate, statistical synthesis acyloin macrocyclization does indeed form mechanically interlocked rings. The lack of direct experimental evidence for Wasserman's catenane has led it being described as "prophetic compound", technical term used patents molecules that have yet been synthesized. Contemporary synthetic methods were reconstruct deuterium-labeled...
The enantioselective domino reaction between CO2 (1 atm), amines and linear allyl chlorides in the presence of an iridium complex, DABCO toluene at 15 °C was realized, which gave branched carbamates acceptable to high yields with up excellent regioselectivity (99/1) 94% ee. This is first example synthesis chiral through catalytic reactions using CO2.
Mechanical bonds are known to efficiently absorb mechanical energy at low forces, but their behavior high forces is unknown. Here we investigate the impact of a bond on rate activation Diels-Alder mechanophore. Using combination experimental and computational techniques, found that retro-Diels-Alder reaction under tension decreased when mechanophore embedded in axle rotaxane due presence competing high-stress region junction between macrocycle axle.
Abstract Three unimolecular peptide channels have been designed and prepared by using the β‐helical conformation of gramicidin A (gA). The new peptides bear one to three NH 3 + groups at N‐end CO 2 − C‐end. These zwitterionic were inserted into lipid bilayers in an orientation‐selective manner. Conductance experiments on planar showed that this orientation bias could lead observable directional K transport under multi‐channel conditions. This behavior can further cause generation a current...
One of the key challenges in engineering neural tissues for cell-based therapies is to develop a biocompatible scaffold material direct stem cell (NSC) behaviors. great advantage would be induce NSC migration toward pathological sites during regeneration and repair. In particular, inflammatory responses zone, which are mainly mediated by microglia central nervous system, affect repair capacity NSCs through migration. Recently, graphene was used as interface material, but few studies have...
1,4-Dioxane promoted O -alkylation of various 1,3-dicarbonyl compounds beyond previous carbene insertion into C–H and C–C bonds has been disclosed.
In vertebrate retina, melatonin regulates various physiological functions. this work we investigated the mechanisms underlying melatonin-induced potentiation of glycine currents in rat retinal ganglion cells (RGCs). Immunofluorescence double labelling showed that RGCs were solely immunoreactive to MT(2) receptors. Melatonin potentiated RGCs, which was reversed by receptor antagonist 4-P-PDOT. The effect blocked intracellular dialysis GDP-beta-S. Either preincubation with pertussis toxin or...