A5018864173- Graphene and Nanomaterials Applications
- Carbon and Quantum Dots Applications
- Tissue Engineering and Regenerative Medicine
- Nanoplatforms for cancer theranostics
- Graphene research and applications
- Advanced biosensing and bioanalysis techniques
- Nerve injury and regeneration
- Electrospun Nanofibers in Biomedical Applications
- Cancer-related molecular mechanisms research
- Quantum Dots Synthesis And Properties
- Neuroscience and Neural Engineering
- Nanoparticles: synthesis and applications
- Pluripotent Stem Cells Research
- Biosensors and Analytical Detection
- Bone Tissue Engineering Materials
- Vagus Nerve Stimulation Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Neuroscience of respiration and sleep
- Supramolecular Self-Assembly in Materials
- Gout, Hyperuricemia, Uric Acid
- IL-33, ST2, and ILC Pathways
- Plant responses to water stress
- Cardiac and Coronary Surgery Techniques
- Genomics, phytochemicals, and oxidative stress
- Plant Stress Responses and Tolerance
Soochow University
2011-2025
Donghua University
2024-2025
Materials Science & Engineering
2025
Nanjing University of Aeronautics and Astronautics
2023-2024
University of Science and Technology of China
2024
Wannan Medical College
2021-2024
Suzhou Institute of Nano-tech and Nano-bionics
2013-2023
Chinese Academy of Sciences
2014-2023
First Affiliated Hospital of Soochow University
2023
Guangzhou University of Chinese Medicine
2020-2022
Small but powerful: NIR-emitting CdTe quantum dots (QDs) are directly prepared in aqueous phase through a one-step microwave synthesis. The QDs display excellent dispersibility, strong luminescence, and high stability. In vitro vivo imaging applications show spectral spatial resolution. efficiently accumulated tumors of live mice (see picture).
Physical cues of the scaffolds, elasticity, and stiffness significantly guide adhesion, proliferation, differentiation stem cells. In addressable microenvironments constructed by three-dimensional graphene foams (3D-GFs), neural cells (NSCs) interact with respond to structural geometry mechanical properties porous scaffolds. Our studies aim investigate NSC behavior on various 3D-GFs. Two kinds 3D-GFs scaffolds present soft stiff elasticity moduli 30 64 kPa, respectively. Stiff scaffold...
Abstract Despite advancements in engineered heart tissue (EHT), challenges persist achieving accurate dimensional accuracy of scaffolds and maturing human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs), a primary source functional cardiac cells. Drawing inspiration from muscle fiber arrangement, three‐dimensional (3D)‐printed multi‐layered microporous polycaprolactone (PCL) scaffold is created with interlayer angles set at 45° to replicate the precise structure native...
Silicon-based active and reproducible surface-enhanced Raman scattering (SERS) substrate, i.e., silver nanoparticles decorated-silicon wafers (AgNPs@Si), is employed for constructing high-performance sensors. Significantly, the AgNPs@Si, facilely prepared via in situ AgNPs growth on silicon wafers, features excellent SERS reproducibility high enhancement factor. Our experiment further demonstrates such resultant silicon-based substrate efficacious multiplex, sensitive, specific DNA...
Metal pollution has been widely reported in mangrove wetlands; however, the mechanisms involved metal detoxification by mangroves are still poorly understood. This study aimed to investigate possible function of root anatomy and lignification/suberization on uptake tolerance seedlings six species mangroves. The results revealed that three rhizophoraceous (Bruguiera gymnorrhiza (L.) Poir, Kandelia obovata Sheue, Liu & Yong Rhizophora stylosa Griff) consistently exhibited higher tolerances...
Surface-enhanced Raman scattering (SERS) is well recognized as a powerful analytical tool, enabling ultrahigh sensitive detection of analytes at low concentrations, even down to single-molecule level. Of particular note, in comparison sufficient investigations on SERS-based biomolecules (e.g., DNA and protein), there has been relatively scanty information regarding vitro vivo detection. In this Article, we demonstrate kind SERS-active substrate, i.e., AgNPs-decorated silicon wafer...
One of the key challenges in engineering neural tissues for cell-based therapies is to develop a biocompatible scaffold material direct stem cell (NSC) behaviors. great advantage would be induce NSC migration toward pathological sites during regeneration and repair. In particular, inflammatory responses zone, which are mainly mediated by microglia central nervous system, affect repair capacity NSCs through migration. Recently, graphene was used as interface material, but few studies have...
Cell-derived extracellular matrix exhibits excellent adhesion performance for neural progenitor cell anchoring and residency, resulting in promoted proliferation of the stem cells to basal forebrain cholinergic neurons.
Preeclampsia is a life-threatening multiorgan systemic disease with manifestations including gestational hypertension, oxidative stress, and vascular dysfunction. We aimed to evaluate the therapeutic effects of melatonin on an L-NAME (NLG-nitro-l-arginine methyl ester)-induced rat preeclampsia model. During gestation, was added drinking water at 50 mg/kg/day from gestation day (GD) 8. Rats received combination (10 mg/kg/day), or aspirin (1.5 rats that only no treatments were used as...
Abstract The collective light-matter interaction of chiral supramolecular aggregates or molecular ensembles with confined light fields remains a mystery beyond the current theoretical description. Here, we programmably and accurately build models plasmonic complexes, aiming to uncover entangled effects excitonic correlations, intra- intermolecular charge transfer, localized surface plasmon resonances. intricate interplay multiple chirality origins has proven be strongly dependent on...
The various complex needs for assistance among home-based older adults have increased dramatically. Thus, it would be advantageous to recruit volunteers with medical knowledge and a better understanding support assist the elderly living in urban communities.This study aimed explore experiences expectations of receiving volunteer services Chinese areas. DESIGN, SETTING AND PARTICIPANTS: A descriptive qualitative was conducted following Consolidated Criteria Reporting Qualitative Research...
Klein aber fein: Im Nahinfrarot emittierende CdTe-Quantenpunkte (QDs) werden direkt in wässriger Phase einer einstufigen Mikrowellensynthese hergestellt. Die Quantenpunkte sind hervorragend Wasser dispergierbar und zeigen starke Lumineszenz hohe Stabilität. Bildgebende In-vitro- In-vivo-Anwendungen ergeben eine spektrale räumliche Auflösung. wirksam Tumoren lebender Mäuse akkumuliert (siehe Bild).
Betatrophin is a recently identified protein that has been shown to be associated with lipid metabolism and insulin resistance. This study aimed measure serum betatrophin concentrations in patients type 2 diabetes (T2DM) evaluate the association of diabetic retinopthy (DR). Serum were compared between (1) gender-, age- body mass index-matched T2DM (n=17) or without (n=33) DR; (2) age-, healthy subjects (n=31), newly-diagnosed before treatment (n=24), under antidiabetic (n=35). determined by...
Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from root Salvia miltiorrhiza Bunge. Osteosarcomas are primary malignant tumors bone. The aim our study to explore role Tan in osteosarcomas survival, migration, and proliferation. MG63 osteosarcoma cell line was cultured vitro treated with different concentrations IIA. Then, ELISA, immunofluorescence, qPCR, western blots, pathway analysis were conducted verify whether II modulated proliferation through...
Yes‑associated protein (YAP) is a conserved transcriptional coactivator that plays key roles in controlling organ size, tumorigenesis and drug resistance. Emerging evidence shows YAP overexpressed associated with resistance to BRAF inhibitor treatment melanoma. However, the mechanism accounting for YAP‑overexpression melanoma largely unknown. The present study characterized ubiquitin‑specific peptidase 22 (USP22) as deubiquitinase abundance biological functions Using western blotting...
Background: Ischemic stroke is the most common cause of ischemia-related death globally. Brain injuries due to and trauma are typically followed by inflammation reactions within central nervous system (CNS). Neural stem cell (NSC)-based therapeutic strategies show great potential for treating ischemia-mediated brain injuries, migration NSCs a critical step involved in NSC-based therapy.
 Methods: In order examine effects microglial activation upon ischemia on NSC behaviors,...