Xiaohong Xu

ORCID: 0000-0001-7683-4472
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About
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Research Areas
  • Gastrointestinal motility and disorders
  • Heart Rate Variability and Autonomic Control
  • Diet and metabolism studies
  • Acupuncture Treatment Research Studies
  • Infant Health and Development
  • Urinary Bladder and Prostate Research
  • Sexual function and dysfunction studies
  • Gastroesophageal reflux and treatments
  • Cancer-related Molecular Pathways
  • Protein Tyrosine Phosphatases
  • Cardiovascular and exercise physiology
  • Heart rate and cardiovascular health
  • Obstructive Sleep Apnea Research
  • Non-Invasive Vital Sign Monitoring
  • Music Therapy and Health
  • Vagus Nerve Stimulation Research
  • Neuroscience of respiration and sleep
  • Dysphagia Assessment and Management
  • Sex and Gender in Healthcare
  • Ginseng Biological Effects and Applications
  • Anesthesia and Neurotoxicity Research
  • Cardiovascular Syncope and Autonomic Disorders
  • Biochemical effects in animals
  • Pharmacology and Obesity Treatment
  • Clinical Nutrition and Gastroenterology

Tianjin Medical University
2025

Zhejiang Chinese Medical University
2020-2023

Oklahoma Medical Research Foundation
2013

The University of Texas Medical Branch at Galveston
2002-2012

Peking Union Medical College Hospital
2006-2009

Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2009

Background acupuncture (AP) has been shown to have a therapeutic potential for gastrointestinal motility disorders. The aims of this study were investigate the effects and possible mechanisms on postprandial upper lower abdominal symptoms induced by rectal distension (RD). Twenty healthy volunteers involved in two-session (AP sham-AP, AP no-AP, or sham-AP no-AP). In 12 volunteers, RD was performed 60 min state, at ST36 during second 30-min period RD. Gastric slow waves heart rate variability...

10.1152/ajpregu.00301.2010 article EN AJP Regulatory Integrative and Comparative Physiology 2012-05-17

Background Rectoanal inhibitory reflex (RAIR) is routinely assessed in anorectal manometry and of clinical value the diagnosis patients with constipation. However, no quantitative analysis currently available for assessment RAIR. The aim this study was to evaluate diagnostic RAIR Methods Nine healthy subjects, 22 constipation (CO) 26 fecal incontinence (FI) were enrolled study. solicited by inflating balloon various volumes from 10 50 mL. percentage relaxation determined on basis rectal...

10.1097/mcg.0b013e31814927ba article EN Journal of Clinical Gastroenterology 2008-07-01

Abstract Background and Aim: The aim of this study was to investigate the effect enhanced viscosity on gastric emptying gastrointestinal motor myoelectrical activities in dogs. Method: performed eight healthy female hound dogs chronically implanted with four pairs two intestinal serosal electrodes a duodenal fistula. Each dog studied three sessions fed test meals different viscosity. Gastric monitored for 2 h simultaneously recordings. Results: liquid meal containing either 0.78% or 1.21%...

10.1111/j.1440-1746.2005.03604.x article EN Journal of Gastroenterology and Hepatology 2005-02-24

Constipation, a gastrointestinal function disorder, is one of the side effects paclitaxel (PTX) chemotherapy. Shenhuang plaster (SHP) application on Shenque acupoint promotes gut motility in clinical settings. In this study, we elucidated ingredients SHP and evaluated its PTX-induced constipation using tumour-bearing mouse model. was prepared traditional Chinese preparation method. The were analysed UPLC-MS/MS identified via screening standard drug database. transit by movement...

10.1155/2020/2383970 article EN cc-by Journal of Immunology Research 2020-07-11

Postoperative ileus (POI), a gastrointestinal function disorder, is complication that arises from surgery. Shenhuang plaster (SHP) application to the Shenque acupoint (CV8) promote recovery of has achieved definite curative effects in clinical settings; however, underlying pharmacological mechanism remains unknown. In this study, we evaluated SHP using Sprague Dawley rat POI model. Then, transit different groups was by movement fluorescein-labelled dextran. Ghrelin, obestatin, motilin (MTL),...

10.1155/2021/8859579 article EN Evidence-based Complementary and Alternative Medicine 2021-06-01

Abstract The aim of this study was to investigate the effects sildenafil on gastric motility and slow waves in dogs. performed healthy dogs composed three experiments. first experiment designed emptying waves. second used tone. third postprandial antral contractions. (i) Sildenafil did not alter liquid. (ii) had no dominant frequency percentage normal power was, however, significantly reduced with ( P < 0.02). (iii) Fasting volume higher than that at baseline 0.0005) or control session...

10.1111/j.1365-2982.2006.00893.x article EN Neurogastroenterology & Motility 2007-02-12

Lung cancer, particularly non-small cell lung cancer (NSCLC) which contributes more than 80% to totally cases, remains the leading cause of death and 5-year survival is less 20%. Continuous understanding on mechanisms underlying pathogenesis this disease identification biomarkers for therapeutic application response treatment will help improve patient survival. Here we found that a molecule known as DUSP10 (also MAPK phosphatase 5) oncogenic in NSCLC. Overexpression NSCLC cells resulted...

10.4110/in.2023.23.e34 article EN Immune Network 2023-01-01

The aims of this study were to utilize multi‐channel electrogastrography (MEGG) and power spectra analysis Heart Rate Variability (HRV) investigate the effects test meal on MEGG autonomic nervous system (ANS) function in patients with gastroesophageal reflux disease (GERD). Methods: Sixteen diagnosis GERD enrolled (11 M, 5 F, mean age: 47 yrs) 16 healthy subjects (HS) matched for age gender recruited as control yrs). was recorded simultaneously electrocardiogram (ECG) recording 30 min...

10.1111/j.1365-2982.2006.00789_28.x article EN Neurogastroenterology & Motility 2006-05-12
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