A5016877332- Healthcare Systems and Public Health
- Adipokines, Inflammation, and Metabolic Diseases
- Human Health and Disease
- COVID-19 Clinical Research Studies
- Cardiovascular Disease and Adiposity
- Sodium Intake and Health
- Long-Term Effects of COVID-19
- Blood Pressure and Hypertension Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Apelin-related biomedical research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lipoproteins and Cardiovascular Health
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Smoking Behavior and Cessation
- Spaceflight effects on biology
- Heart Rate Variability and Autonomic Control
- Thermoregulation and physiological responses
- Biomarkers in Disease Mechanisms
- Birth, Development, and Health
- Climate Change and Health Impacts
- Thermal Regulation in Medicine
- Urban Transport and Accessibility
Institute of Cytology and Genetics
2022-2025
Research Institute of Therapy and Preventive Medicine
2025
Siberian Branch of the Russian Academy of Sciences
2023-2024
Aim of the study was to investigate main epidemiological characteristics hypertension (HTN), as well factors associated with HTN, in male rural population 35–74 years old Novosibirsk. Material and methods . On basis Research Institute Internal Preventive Medicine — Branch Cytology Genetics, Siberian Russian Academy Sciences, 2021–2023, a one–stage urban Novosibirsk region conducted according protocol “Epidemiology cardiovascular diseases their risk Federation. The third study”. A total 1,800...
Aim. To analyze the association of neighborhood infrastructure with cardiovascular diseases (CVDs) and their risk factors (RFs) in a representative all-Russian adult population sample. Material methods . Data from ESSE-RF3 study conducted 2020-2022 15 Russia regions were used. The total sample included 28731 men women aged 35-74 years. was assessed using Russian version (Neighborhood Environmental Walkability Scale (NEWS). following CVDs assessed: hypertension, obesity, hypercholesterolemia,...
Aim. To study the prevalence of non-alcoholic fatty liver disease (NAFLD) and its association with cardiovascular risk factors (RFs). Material methods. The database from ESSE-RF2 ESSE-RF3 epidemiological studies was used, including data surveys population aged 35-64 years in 18 Russian regions (n=21204). assess NAFLD, index (FLI) used. Statistical analysis performed using statistical programming language R environment (version 3.6.1) open-source code. significance level for all tested...
The article presents a review of the literature devoted to analysis influence natural and climatic factors on human body. We analyzed parameters such as ambient temperature, including effects heat cold, well fluctuations in atmospheric pressure humidity levels. A number studies have demonstrated significant impact both increase decrease temperature relative comfort level, correlation with has been established. these functioning cardiovascular, respiratory nervous systems were considered....
Aim . To study the content of unsaturated fatty acids (FAs) in blood plasma men from Novosibirsk (ESSERF3 region) with established type 2 diabetes mellitus (DM2), newly diagnosed diabetes, and prediabetes, as well to evaluate associations various types FAs presence or absence fasting glucose levels. Materials methods Within framework multicenter, single-stage epidemiological ESSE-RF3 region, 1 200 residents (600 men, 600 women) aged 35–74 years were examined. The present included 563 an...
Objective. To study the associations of fragmented QRS (fQRS) with cardiometabolic risk factors in a sample Novosibirsk residents. Material and methods. There were 982 residents (477 (48.6%) men) aged 35-74 years. Survey program included demographic social data, anthropometry, blood pressure electrocardiography. Cardiometabolic determined according to appropriate criteria (2013). The fQRS lower left ventricular wall was used. Results. 119 people (12.1%). It more common men (83/477 (17.4%)...
The pathogenesis of the development chronic lung diseases assumes participation systemic inflammation factors, as well hormone-like substances produced by adipose tissue. aim this study was to evaluate associations certain adipokines/cytokines and bronchitis against background abdominal obesity in young people. included 1415 people aged 25-44. In total, 115 were selected random numbers method, who divided into two subgroups: those with without obesity. A control group patients comparable...
It is important to determine the influence of traditional risk factors on development type 2 diabetes mellitus (T2DM) in young adults. Goal research: To study incidence T2DM and that increase its occurrence during observation a cohort adults.1341 people aged 25-44 were included from 2013 2017, whom 622 men (46.4%). The examination anamnesis, anthropometric data, blood test. Cases developed identified by comparing Diabetes Mellitus Register, medical records patients, database examined...
Aim. To evaluate the associations of abdominal obesity (AO), adipokines and premature coronary artery disease (CAD) in young people for a deeper understanding pathogenesis atherosclerotic diseases. Material methods. A total 1457 were examined, including 653 (44,8%) men. Mean age was 36,7±6,0 years. Premature CAD detected 46 people, while 4 following subgroups formed (138 total): with AO; CAD, without control groups by sex: AO. Results. is associated an increase non-high-density lipoprotein...
Discussions continue about the effect of arterial hypertension (AH) on course and prognosis COVID-19 infection, while interest in antihypertensive therapy (AHT), primarily angiotensin converting enzyme inhibitors (ACEI) receptor blockers (ARB), disease does not weaken. Aim study was to investigate associations AH, AHT severity coronavirus infection Novosibirsk patients. Material methods. Study design: a single-stage observational study. The included 268 patients aged 26–84 years (47.5 % men)...
There are data supporting the idea that atherogenic dyslipidemia is a risk factor for CKD and reduced GFR. The aim was to evaluate associations between adipocytokines early renal dysfunction in young people with dyslipidemia.A population study conducted IIPM-Branch of IC&G SB RAS, 2013-2017. Furthermore, 1033 were included (469 men (45.4%) 564 women (54.6%)). blood sampling, anthropometric data, adipokines by multiplex analysis.Among kidney function DLP, 3.1 times more common than without...
In 2020, the National Institute for Health and Care Excellence in UK proposed concept of post-Covid syndrome. One main manifestations post-COVID syndrome are cardiovascular diseases (CVD) dyslipidemia. However, pathogenetic patterns CVD development COVID-19 convalescents remain unclear. The purpose systematic review was to analyze research data on contribution past new coronavirus infection dyslipidemia atherosclerosis-associated (AAD) period. 106 publications were selected analysis. After...
Aim. To study the prevalence and risk factors of hypertension (HTN), structure effectiveness treatment coverage, as well disease control indicators among male population aged 35-74 years in Novosibirsk. Material methods . This cross-sectional Novosibirsk was conducted 2021-2023 at Research Institute for Internal Preventive Medicine — branch Federal Center Cytology Genetics according to ESSE-RF3 protocol. A total 1200 people living were examined. The analysis included 600 men. response rate...
Aim . To study the associations of abdominal obesity (AO), levels biochemical markers chronic and acute inflammation, post-COVID syndrome (PCS) in coronavirus disease 2019 (COVID-19) convalescents. Material methods The cross-sectional observational included 166 people aged 18-84 (44,6% men) who were COVID-19 convalescents. In all patients, medical history anthropometric data collected. AO was defined as waist circumference >80 cm women >94 men. blood serum, concentrations following...
This review presents the results of investigations in field studying association adipokines secreted by visceral adipocytes and level low-density lipoprotein cholesterol. In relation to this association, such as adiponectin, plasminogen activator inhibitor 1 (PAI-1), resistin, interleukin beta (IL-1β), monocyte-chemoattractant protein type (MCP-1), nerve growth factor (NGF), visfatin, omentin-1, pancreatic hormone insulin were analyzed. The studies that have studied pathogenetic (in animal...
This review presents the results of research in field studying associations biochemical and molecular genetic markers kidney damage arterial hypertension. Information on topic from publications PubMed, Google Scholar databases was used.
The purpose of this review is to describe the available scientific data on post-COVID-19 syndrome, formulate main approaches classification, determine potential mechanisms its pathogenesis, as well occurrence bronchopulmonary system pathology within framework syndrome. It known that long-term persistence COVID-19 symptoms significantly reduces quality life patients through direct or indirect effect SARS-CoV-2 virus a number organs and systems. examines in detail possible pathogenetic...
The prevalence of arterial hypertension (HTN), which is one the most important risk factors (RF) for cardiovascular diseases (CVD), still increasing, represents a global problem world health, because many decades CVD have occupied leading position in structure mortality throughout world. This article reviews main epidemiological studies available by end 2023, analyzed various indicators HTN both Russia and around world, with aim developing an understanding time trends HTN. also analyzes RF...
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The research was aimed to study the associations of adipocytokines with risk cardiovascular events and determine threshold values adipocytes for prognosis in a young population. is an epidemiological cohort study. analysis included 1240 people aged 25-44 years. endpoint combined included: death from disease, myocardial infarction, probable acute cerebrovascular accident, hospitalization revascularization. Adipocytokines were determined MILLIPLEX panel. In examined population, 1.7% cases...
The purpose of this review was to find an answer the question: “Is there association adipokines (adiponectin, adipsin, interleukin-6, lipocalin-2, PAI-1, resistin, MCP-1, leptin, TNF-α, visfatin, omentin-1) with coronary artery disease and abdominal obesity in people under 65 years age?”. Articles investigating patients aged 18 heart were included. analysis included only publications last 10 (2013–2023). As a result analyzed literature, most are devoted studies conducted on persons over age....