A5100774438- Sugarcane Cultivation and Processing
- Biofuel production and bioconversion
- Rice Cultivation and Yield Improvement
- Plant nutrient uptake and metabolism
- Genetic Mapping and Diversity in Plants and Animals
- Monoclonal and Polyclonal Antibodies Research
- Plant Molecular Biology Research
- Natural Products and Biological Research
- Genomics and Phylogenetic Studies
- Advanced Data Storage Technologies
- Cancer, Hypoxia, and Metabolism
- Cocoa and Sweet Potato Agronomy
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Plant Stress Responses and Tolerance
- Cancer Genomics and Diagnostics
- Inflammatory Biomarkers in Disease Prognosis
- Birth, Development, and Health
- Heavy metals in environment
- Epigenetics and DNA Methylation
- Light effects on plants
- RNA and protein synthesis mechanisms
- Dental Implant Techniques and Outcomes
- Mercury impact and mitigation studies
- Animal Genetics and Reproduction
Nanjing Agricultural University
2019-2024
Hunan University of Science and Technology
2020-2024
Soil and Fertilizer Institute of Hunan Province
2022
Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences
2022
Fujian Agriculture and Forestry University
2014-2020
Xiangya Hospital Central South University
2018
Central South University
2018
Peking University
1989-1991
Peking University Cancer Hospital
1989-1991
Abstract Over-application of nitrogen fertilizer in fields has had a negative impact on both environment and human health. Domesticated rice varieties with high use efficiency (NUE) reduce for sustainable agriculture. Here, we perform genome-wide association analysis diverse population displaying extreme nitrogen-related phenotypes over three successive years the field, identify an elite haplotype nitrate transporter OsNPF6.1 HapB that enhances uptake confers NUE by increasing yield under...
Increased use of nitrogen fertilizers has deleterious impact on the environment. Increase in yield potential at low supply is regarded as a cereal breeding goal for future agricultural sustainability. Although natural variations transporters have been investigated, key genes associated with assimilation remain largely unexplored efficiency (NUE) enhancement. Here, we identified NIN-like protein NLP4 NUE through GWAS rice. We found that OsNLP4 transactivated OsNiR encoding nitrite reductase...
Abstract Excessive nitrogen promotes the formation of nonproductive tillers in rice, which decreases use efficiency (NUE). Developing high-NUE rice cultivars through balancing uptake and productive remains a long-standing challenge, yet how these two processes are coordinated elusive. Here we identify transcription factor OsGATA8 as key coordinator tiller rice. negatively regulates by repressing ammonium transporter gene OsAMT3.2 . Meanwhile, it OsTCP19 , negative modulator tillering. We -H...
Hotspot mutations of isocitrate dehydrogenase 1 and 2 (IDH1/2) have been studied in several cancers.However, the function wild-type IDH2 lung cancer mechanism its contribution to growth cells remain unknown.Here, we explored role promoting cancer.Methods: Information regarding genomic clinical application focusing on was examined databases more than 1,000 tumor samples.IDH2 expression assessed by immunohistochemistry tissues from patients.The biological functions were evaluated using...
Excessive nitrogen fertilizer application is harmful to the environment and reduces quality of cereal crops. Maintaining crop yields under low (LN) conditions improving are important goals for breeding. Although effects assimilation on nitrogen-use efficiency (NUE) have been intensively studied, natural variations key genes underlying grain development largely unclear. Here, we identified an NUE-associated gene, OsGS1;1, encoding glutamine synthase, through genome-wide association analysis,...
Sugarcane (Saccharum spp. hybrids) is considered the most globally important sugar-producing crop and raw material for biofuel. Insect attack a major issue in sugarcane cultivation, resulting yield losses sucrose content reductions. Stem borer (Diatraea saccharalis F.) causes serious worldwide. However, insect-resistant germplasms are not available any collections all over world, molecular mechanism of insect resistance has been elucidated. In this study, cry1Ac transgenic lines were...
Heterosis QTLs, including qSS7 and qHD8, with dominance effects were identified through GBS large-scale phenotyping of CSSLs hybrid F1 populations in a paddy field. has contributed immensely to agricultural production, but its genetic basis is unclear. We evaluated by creating two populations: B-homo set homozygous background heterozygous chromosomal segments B-heter segments. This was achieved crossing 156 backcrossed-derived chromosome segment substitution lines (CSSLs) their recurrent...
Modern sugarcane cultivars are highly polyploid with complex nuclear genomic genetic background, while their mitochondrion (mt) genomes much simpler, smaller and more manageable could provide useful phylogenetic information. In this study, the mt genome of a modern commercial cultivar A1 was sequenced via Illumina Hiseq XTen PacBio Sequel platform. The assembled annotated mitochondrial were composed two circular DNA molecules, one large small, which named Chromosome 1 2. distinct chromosomes...
The VQ motif-containing proteins play a vital role in various processes such as growth, resistance to biotic and abiotic stresses development. However, there is currently no report on the genes sugarcane (Saccharum spp.). Herein, 78 Saccharum spontaneum were identified classified into nine subgroups (I-IX) by comparative genomic analyses. Each subgroup had similar structural conservative motif. These expanded mainly through whole-genome segmental duplication. cis-regulatory elements (CREs)...
Abstract Rice is the most important cereal crop but sensitive to salinity stress. Increased salinization progressively reducing rice productivity, escalating calls for research ensure sustainable food production. The genetic diversity available in cultivars provides a rich resource discovering genes associated with salt tolerance which has not yet been sufficiently utilized. In this study, 54 QTLs were detected through genome‐wide association study (GWAS) using core population consisting of...
A total of 100 Sporisorium scitamineum isolates were investigated by inter simple sequence repeat (ISSR) and single primer-sequence related amplified polymorphism (SP-SRAP) markers. These clearly assorted into three distinct clusters regardless method used: either cluster analysis or principal component (PCA) the ISSR, SP-SRAP, ISSR + SP-SRAP data set. The gene diversity (H t) between subpopulations s) estimated to be 0.34 0.38 0.22 0.29, respectively, analyzing separately sets, 0.26-0.36...
FHY3 and FAR1 serve as positive regulators of the phyA-mediated far-red light signal pathway, influencing plant growth development by regulating expression downstream genes. However, little is known about FAR1/FHY3 family in Brassica species. A total 21 members BnFAR1/FHY3 gene were identified napus genome, exhibiting an uneven distribution across ten B. chromosomes. phylogenetic analysis showed that could be divided into four subfamilies. Putative cis-elements promoter regions also...
In plants, the multi-gene family of dual-function hexokinases (HXKs) plays an important role in sugar metabolism and sensing, that affects growth stress adaptation. Sugarcane is sucrose crop biofuel crop. However, little known about HXK gene sugarcane. A comprehensive survey sugarcane HXKs, including physicochemical properties, chromosomal distribution, conserved motifs, structure was conducted, identifying 20 members SsHXK were located on seven 32 Saccharum spontaneum L. chromosomes....
The complete mitogenome of Saccharum spp. hybrid ROC22 (a modern sugarcane cultivar) was sequenced and analyzed in the present study. Our results revealed that, unlike most plants, contains two distinct circular chromosomes, Chromosome 1 2. length is 300,837 bp with GC content 43.93%, 2 144,755 43.57%. Apart from 16 tRNAs six rRNAs non-coding genes, there are 20 protein-coding genes 1, including nad four rps three atp ccm cox one mat gene mtt gene. 18 five tRNA 13 (four gene, cob rpl gene)....
The complete mitogenome of Saccharum spp. hybrid FN15 was successfully sequenced. It contains two distinct circular chromosomes, Chromosome 1 and 2. former is 301,533 bp in length with the GC content 43.90%, 7.12% genome (21,468 nucleotides) are coding DNA while 92.88% (280,065 intergenic region. latter 144,744 43.57%, 8.20% (11,865 91.80% (132,879 Besides, 22 protein-coding genes (four atp genes, three ccm cox one mat gene, mtt six nad four rps genes), 21 non-coding (15 tRNA rRNAs), whereas...
The complete mitogenome of Saccharum spp. hybrid 15a-53 was determined in this study, which contains two distinct circular chromosomes, Chromosome 1 and 2. length is 300,848 bp with the GC content 43.93%, while 2 144,713 43.57%. In 1, 7.14% genome (21,468 nucleotides) coding DNA 92.86% (279,380 are intergenic region, 2, 8.20% (11,865 91.80% (132,848 region. 20 protein-coding genes (three atp genes, three ccm cox one mat gene, mtt six nad four rps genes), 21 non-coding (15 tRNA rRNAs), there...
Spleen cells from Balb/c mice immunized with five human gastric cancer cell lines in sequence were fused murine myeloma line SP2/0, and hybridomas 3F4, 3G9 3H11, secreting monoclonal antibodiees (MoAbs) against cancer, obtained through selective culture screening. These MoAbs have both good selectivity a high positive rate of reaction for reaching 5/5 84.8% to 93.5% tissues respectively. The normal was neglible. corresponding antigens the sensitive digestion by trypsin pronase resistant...
Objective To investigate the effect of infused CD34+ cell count on hematopoietic recovery and prognosis non-Hodgkin lymphoma (NHL) patients after autologous peripheral blood stem transplantation (APBSCT). Methods The data 60 NHL who underwent APBSCT from May 2010 to 2016 in Affiliated Cancer Hospital Shanxi Medical University was retrospectively analyzed, including 32 B-NHL 28 T-NHL patients. The were grouped according receiver operating characteristic curve (ROC) threshold,...
The localization of three monoclonal antibodies (MAb) against gastric cancer was studied on two human cell lines by immunoelectron microscopic technique. It has shown that the corresponding antigens MAb 3G9 and 3H11 were distributed microvilli (M) non-microvillus (NM) plasma membrane target cells, with various M to NM ratios depending MAbs cells used. However, PD4 only localized surface round or finger-like bulges never non-microvillous membrane. Since nature function these tumor have not...