A5016872439- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Hormonal Regulation and Hypertension
- Cardiac Valve Diseases and Treatments
- Heart Rate Variability and Autonomic Control
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Cardiac tumors and thrombi
- Takotsubo Cardiomyopathy and Associated Phenomena
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiovascular Disease and Adiposity
- Renin-Angiotensin System Studies
- Infective Endocarditis Diagnosis and Management
- Sodium Intake and Health
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Lipoproteins and Cardiovascular Health
- Vasculitis and related conditions
- Aortic Disease and Treatment Approaches
- Non-Invasive Vital Sign Monitoring
- Medication Adherence and Compliance
Kyung Hee University Hospital at Gangdong
2015-2024
Kyung Hee University
2011-2024
Central Research Institute
2023
Weatherford College
2019
Seoul Medical Center
2017
Creative Commons
2016
Kyung Hee University East-West Neo Medical Center
2006-2011
Seoul National University Hospital
2009-2010
Kyung Hee University Medical Center
2010
Chonnam National University Hospital
2005-2007
A number of distinct stress signaling pathways in myocardium cause cardiac hypertrophy and heart failure. Class II histone deacetylases (HDACs) antagonize several stress-induced hypertrophy. However, induced by transgenic overexpression the homeodomain only protein, HOP, can be prevented nonspecific HDAC inhibitors trichostatin valproic acid, suggesting that alternate targets oppose class function might exist myocardium. We tested effects inhibitors, including a I HDAC-selective inhibitor,...
Curcumin, a yellow pigment of turmeric in curry, is reported to interfere with nuclear factor (NF)-κB. This study was designed investigate the underlying pathway antiinflammation curcumin on endothelial cells. Human umbilical vein cells (HUVECs) were stimulated 10 ng/mL tumor necrosis (TNF)-α. Curcumin blocked activation NF-κB by TNF-α. also reduced intracellular reactive oxygen species (ROS), monocyte adhesion, phosphorylation c-Jun N-terminal kinase (JNK), p38, and signal transducer...
Abstract Smartphone technology has spread rapidly around the globe. According to a report released by Korea Information Society Development Institute, about 95% of Koreans aged more than 30 years old owned smartphones. Recently, blood pressure (BP) measurement using photoplethysmography-based smartphone algorithm paired with smartwatch is continuously evolving. In this document, Korean Hypertension intends remark current results / smartwatch-based BP and recommend optimal methods device. We...
In several recent clinical trials on cardiac surgery patients, remote ischaemic preconditioning (RIPC) showed a powerful myocardial protective effect. However the effect of RIPC has not been studied in patients undergoing off-pump coronary artery bypass graft surgery. We evaluated whether could induce protection patients. Patients elective were randomly allocated to (n = 65) or control group 65). After induction anaesthesia, was induced by four cycles five-minute ischaemia and reperfusion...
Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for remain elusive. We aimed to present with reservoir, conduit, contractile components associated parameters in large-sized group healthy individuals.The study was from prospective multicenter registry South Korea. Subjects who had no history cardiovascular disease adequate images were eligible inclusion. strains (LASRES, LASCD LASCT, respectively)...
Objectives: The objective of the study was to test whether acupuncture improves endothelial dysfunction in patients with hypertension and compare effects different acupoints find out which one is most suitable for long-term follow-up study. Design: This a pilot, randomized, double-blind, placebo-controlled crossover trial. Subjects were randomly assigned sequence four treatment phases, each 15 minutes 7-day washout period between. Acupuncture needles inserted at bilateral ST 36; PC 6; 36...
The objective of the study was to investigate effect acupuncture on circadian rhythm blood pressure (BP) in patients with hypertension.The designed as a randomized, double-blind, controlled trial. Subjects were randomly divided into an active group and sham group. Each patient received real or treatment twice week for 8 weeks. Acupuncture needles inserted at bilateral ST 36 plus PC 6; placebo points.Thirty-three (33) essential hypertension subjects.Twenty-four (24)-hour ambulatory BP...
Measurement of the cardiac chamber is essential, and current guidelines recommend measuring reporting values for both sides during echocardiographic evaluation. Normal reference have been suggested previously, but detailed information about right-sided chambers according to gender was not included. This a prospective multicenter (23 centers) study evaluating normal Korean adult subjects using comprehensive echocardiography. We included (age; 20-79 years old) who had no significant disorders...
Standard conventional echocardiographyEchocardiographic images were acquired and measured at each institute according to a standard method outlined by the American Society of Echocardiography. 15)All echocardiographic parameters averaged Background: It is important understand distribution 2-dimensional strain values in normal population.We performed multicenter trial measure Korean population.Methods: This was substudy Normal echOcardiogRaphic Measurements KoreAn popuLation (NORMAL)...
The intratubular renin-angiotensin system (RAS) is thought to play an essential role in hypertensive renal disease, but information regarding sex-related differences this limited. present study investigated sex the RAS two-kidney, one-clip (2K1C) rats. A 2.5-mm clip was placed on left artery of Sprague-Dawley rats, and rats were euthanized 3 or 5 wk after operation. Systolic blood pressure increased 2K1C both sexes significantly higher male than female antihypertensive effect not observed...
We sought to assess the association between common antihypertensive drugs and risk of incident cancer in treated hypertensive patients. Using Korean National Health Insurance Service database, incidence was analyzed patients with hypertension who were initially free used following drug classes: Angiotensin-converting enzyme inhibitors (ACEIs); angiotensin receptor blockers (ARBs); beta (BBs); calcium channel (CCBs); diuretics. During a median follow-up 8.6 years, there 4513 (6.4%) overall...
Background Socioeconomic status is associated with differences in risk factors of cardiovascular disease and increased risks mortality. However, it unclear whether an association exists between income, a common measure socioeconomic status, among patients hypertension. Methods Results This population-based longitudinal study comprised 479 359 aged ≥19 years diagnosed essential Participants were categorized by income blood pressure levels. Primary end point was all-cause mortality secondary...
The intrarenal renin-angiotensin system (RAS) has an important role in generating and maintaining hypertension two-kidney, one-clip (2K1C) rats. This study evaluated how various RAS components contributed to not only the maintenance period (5w; 5 wk after operation) but also earlier (2w; 2 operation). We inserted a 2.5-mm clip into left renal artery of Sprague-Dawley rats euthanized them at 2w 5w following operation. Systolic blood pressure increased within 1 operation, ventricular...
Hemodynamic and functional evaluation with Doppler tissue study as a part of comprehensive echocardiography is essential but normal reference values have never been reported from Korean population especially according to age sex. Using Normal echOcaRdiographic Measurements in KoreAn popuLation subjects, we obtained for including tricuspid annular velocities current guidelines compared gender groups. Mitral early diastolic (E) late (A) velocity well E/A ratio were significantly higher women...
While the disease course of stress-induced cardiomyopathy (SIC) is usually benign, it can be fatal. The prognostic factors to predict poorer outcome are not well established, however. We analyzed Acute Physiology And Chronic Health Evaluation (APACHE) II score assess its value for predicting poor prognosis in patients with SIC. Thirty-seven consecutive SIC were followed prospectively during their hospitalization. Clinical factors, including APACHE score, coronary angiogram, echocardiography...
Background: This study was conducted to determine the early cardiac valvular changes in young male ankylosing spondylitis (AS) patients.Methods: A total of 70 AS patients on treatment without clinical symptoms were divided into group I (< 10 years, n = 50) and II (≥ 20) depending their disease duration after first diagnosis.Twenty-five healthy volunteers selected as control subjects.All subjects underwent transthoracic transesophageal echocardiography, electrocardiography, rheumatologic...
In this report, we introduce a case of thickening the involved left ventricular apical segment on echocardiography and deep T‐wave inversions in precordial leads electrocardiography transiently seen course recovery from biventricular takotsubo cardiomyopathy, mimicking hypertrophic cardiomyopathy. This result suggests that echocardiographic finding transient myocardial edema can be identified by cardiac magnetic resonance imaging Additionally, it persisted few weeks after full functional...
The preferred treatment for patients with ST elevation myocardial infarction (STEMI) is primary percutaneous coronary intervention (PCI). However, not all improve or maintain heart function following PCI, and certain may experience decreased function. present study investigated factors associated left ventricular (LV) dysfunction, improvement deterioration of LV ejection fraction (LVEF) at follow-up echocardiography successful PCI. clinical outcomes PCI were also investigated. assessed 4,044...