Lu Li

ORCID: 0000-0001-8019-0163
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About
Contact & Profiles
Research Areas
  • Animal Genetics and Reproduction
  • Virus-based gene therapy research
  • Genetically Modified Organisms Research
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • Carcinogens and Genotoxicity Assessment
  • Parasitic Diseases Research and Treatment
  • PI3K/AKT/mTOR signaling in cancer
  • MicroRNA in disease regulation
  • Effects and risks of endocrine disrupting chemicals
  • Plant Virus Research Studies
  • Medicinal Plants and Neuroprotection
  • Genomics, phytochemicals, and oxidative stress
  • Photosynthetic Processes and Mechanisms
  • Phytochemistry and Bioactivity Studies
  • Plant Molecular Biology Research
  • Molecular Biology Techniques and Applications
  • Cancer Cells and Metastasis
  • Plant Stress Responses and Tolerance

Northeast Agricultural University
2011-2021

The C (Cys) 2H (His) 2-type transcription factor is one of the most important factors in plants and plays a regulatory role physiological responses rice to abiotic stresses. A novel C2H2-type zinc finger protein, abscisic acid (ABA)-drought-reactive oxygen species (ROS) 3 (OsADR3), was found confer drought stress tolerance by enhancing antioxidant defense regulating OsGPX1. Overexpression OsADR3 increased increasing ROS scavenging ability ABA sensitivity. In contrast, CRISPR/Cas9-mediated...

10.1016/j.cj.2020.12.005 article EN cc-by-nc-nd The Crop Journal 2021-01-26

Abstract Glioma, the most predominant primary malignant brain tumor, remains uncured due to absence of effective treatments. Hence, it is imperative develop successful therapeutic agents. This study aimed explore antitumor effects and mechanisms ivermectin (IVM) in glioma cells vitro vivo. The IVM on cell viability, cycle arrest, apoptosis rate, morphological characteristics were determined respectively by MTT assay/colony formation assay, flow cytometry, transmission electron microscope. In...

10.1002/jcb.27420 article EN Journal of Cellular Biochemistry 2018-09-14

Bisphenol A (BPA) has caused serious pathologies in varying organs of humans and animals, especially reproductive organs. Naringenin (NRG) is a flavanone compound that shown protective effects against several environmental chemicals through suppression oxidative stress activation nuclear factor erythroid 2-related 2 (Nrf2) pathway. Herein, we described the discovery path NRG inhibition on apoptosis BPA exposed swine testis (ST) cells targeting Kelch-like ech-associated protein (Keap1). We...

10.1002/biof.1814 article EN BioFactors 2021-12-16
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