A5100774233- IL-33, ST2, and ILC Pathways
- Metal complexes synthesis and properties
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- Ferrocene Chemistry and Applications
- Neonatal Respiratory Health Research
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Eosinophilic Esophagitis
- Click Chemistry and Applications
- Synthesis and biological activity
- Synthesis of Tetrazole Derivatives
- Analytical chemistry methods development
- Bioinformatics and Genomic Networks
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced Glycation End Products research
- Asthma and respiratory diseases
- Macrophage Migration Inhibitory Factor
- Virus-based gene therapy research
- Wound Healing and Treatments
- Enzyme Production and Characterization
- Neuroinflammation and Neurodegeneration Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Identification and Quantification in Food
- Ovarian function and disorders
Guangdong Pharmaceutical University
2016-2025
Chongqing Medical University
2025
Children's Hospital of Chongqing Medical University
2025
Chengdu University
2011-2024
Yangzhou University
2022-2024
Sichuan University
2010-2023
Jiangxi Provincial People's Hospital
2023
First Affiliated Hospital of Jiangxi Medical College
2023
Ningxia Medical University
2017
SynZyme Technologies (United States)
2014
In Th (T helper) 1/Th2 balance in response to signals given during donor antigen presentation, induction of allograft prolongation is more often related Th2-type than with Th1-type immunity. Here, we examined the effect interleukin (IL)-33, a novel member IL-1 family, on cardiac survival mice.Mice heterotopic transplants were performed sequential recipient sacrifice at anticipated time points examine immunoregulatory action IL-33 mice.In vitro Th1-polarized CD4 T cells did not express ST2L;...
A simple, rapid, and efficient method, vortex‐assisted extraction followed by dispersive liquid–liquid microextraction ( DLLME ) has been developed for the of polycyclic aromatic hydrocarbons PAH s) in sediment samples prior to analysis high performance liquid chromatography fluorescence detection. Acetonitrile was used as collecting solvent s from extraction. In , were rapidly transferred acetonitrile dichloromethane. Under optimum conditions, method yields a linear calibration curve...
Abstract Background Interleukin-33 (IL-33) is a well-recognized pleiotropic cytokine which plays crucial roles in immune regulation and inflammatory responses. Recent studies suggest that IL-33 its receptor ST2 are involved the pathogenesis of neurological diseases. Here, we explore effect IL-33/ST2 signaling neonatal hypoxic-ischemic (HI) brain injury elucidate underlying mechanisms action. Methods The HI model was established C57BL/6 mice by left common carotid artery occlusion with 90 min...
The rapid accumulation of data on non-synonymous single nucleotide polymorphisms (nsSNPs, also called SAPs) should allow us to further our understanding the underlying disease-associated mechanisms. Here, we use complex networks study role an amino acid in both local and global structures determine extent which polymorphic SAPs differ terms their interactions other residues. We found that can be well characterized by network topological features. Mutations are probably when they occur at a...
Thymic-derived CD4+CD25+Foxp3+ natural regulatory T (nTreg) cells are essential for the maintenance of peripheral immune tolerance. Signaling pathways that drive immature thymic progenitors to differentiate into nTreg need be elucidated. The precise role TSC1/2 complex, a critical negative regulator mammalian target rapamycin (mTOR), in nTreg-cell develop ment remains elusive. In present study, we found percentage and cell number were significantly increased T-cell-specific TSC1-knockout...
A method using multi-wall carbon nanotubes assisted matrix solid phase dispersion was developed to couple with HPLC-ICP-MS for mercury speciation.
Macamides are a class of amide alkaloids that only found in maca and widely considered to be its bioactive marker compounds. More than thirty macamide monomers have been identified recent years; however, it is difficult obtain single monomer from the plant because their similar structures characteristics. We used carbodiimide condensation method (CCM) efficiently synthesize five typical macamides, including N-benzyl-hexadecanamide (NBH), N-benzyl-9Z,12Z,15Z-octadecenamide,...
In this work, we have carefully designed and synthesized two Ru(II) metal complexes: [Ru(phen)2(HMPIP)](PF6)2 (6a, where phen = 1,10-phenanthroline, HMPIP 2-(2-hydroxy-3-methylphenyl-1H-imidazo[4,5-f][1,10]phenanthroline) [Ru(bpy)2(HMPIP)](PF6)2 (6b, bpy 2,2'-bipyridine). Using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to explore the cytotoxicity of 6a 6b towards HepG2, B16, A549, SGC-7901, HCT116 non-cancer LO2. The complexes exhibited activity against HepG2 cells....