Tong Zhang

ORCID: 0000-0001-8043-237X
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • COVID-19 diagnosis using AI
  • Stock Market Forecasting Methods
  • Energy Load and Power Forecasting
  • Immune Cell Function and Interaction
  • Bayesian Modeling and Causal Inference
  • Grey System Theory Applications
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Multi-Criteria Decision Making
  • Smart Parking Systems Research
  • Toxin Mechanisms and Immunotoxins
  • Pharmacological Effects of Natural Compounds
  • Systemic Lupus Erythematosus Research
  • Mesenchymal stem cell research
  • Lipoproteins and Cardiovascular Health
  • Seismology and Earthquake Studies
  • Artificial Intelligence in Healthcare and Education
  • Data Stream Mining Techniques
  • Statistical Methods and Inference
  • Pharmaceutical Economics and Policy
  • Advanced Radiotherapy Techniques
  • Bone and Dental Protein Studies
  • Forecasting Techniques and Applications
  • Water Quality Monitoring and Analysis

University of Technology Sydney
2025

Chongqing Medical University
2023-2024

Shandong University of Science and Technology
2022

Beijing Jiaotong University
2022

Guangzhou University of Chinese Medicine
2022

Peng Cheng Laboratory
2021

Liaoning University of Traditional Chinese Medicine
2021

General Hospital of Shenyang Military Region
2018

Rutgers, The State University of New Jersey
2009

The state-of-the-art online learning models generally conduct a single gradient descent when new sample arrives and thus suffer from suboptimal model weights. To this end, we introduce an broad system framework with closed-form solutions for each update. Different employing existing incremental algorithms tasks, which tend to incur degraded accuracy expensive update overhead, design effective weight estimation algorithm efficient updating strategy remedy the above two deficiencies,...

10.48550/arxiv.2501.16932 preprint EN arXiv (Cornell University) 2025-01-28

Recent advances in Reinforcement Learning from Human Feedback (RLHF) have shown that KL-regularization plays a pivotal role improving the efficiency of RL fine-tuning for large language models (LLMs). Despite its empirical advantage, theoretical difference between KL-regularized and standard remains largely under-explored. While there is recent line work on analysis objective decision making \citep{xiong2024iterative, xie2024exploratory,zhao2024sharp}, these analyses either reduce to...

10.48550/arxiv.2502.07460 preprint EN arXiv (Cornell University) 2025-02-11

Abstract Hotspot driver mutations presented by human leukocyte antigens might be recognized anti-tumor T cells. Based on their advantages of tumor-specificity and immunogenicity, neoantigens derived from hotspot mutations, such as PIK3CA H1047L , may serve emerging targets for cancer immunotherapies. NetMHCpan V4.1 was utilized predicting neoepitopes mutation. Using in vitro stimulation, antigen-specific cells targeting the HLA-A*11:01-restricted mutation were isolated healthy donor-derived...

10.1007/s00262-024-03729-y article EN cc-by Cancer Immunology Immunotherapy 2024-06-04

This paper develops a theory for group Lasso using concept called strong sparsity. Our result shows that is superior to standard strongly group-sparse signals. provides convincing theoretical justification sparse regularization when the underlying structure consistent with data. Moreover, predicts some limitations of formulation are confirmed by simulation studies.

10.48550/arxiv.0901.2962 preprint EN other-oa arXiv (Cornell University) 2009-01-01

Chest radiographs clearly present the characteristics of lung lesions in patients with new coronary pneumonia, thus they can be leveraged to build a pneumonia detection model provide doctors favorable auxiliary diagnosis results. This paper proposes COVID-19 localization and identification approach based on yolov5 EfficientNet. Due inherent reasons such as computational complexity network structure, features single are usually limited representation, EfficientNet provides competitive feature...

10.1109/icsp54964.2022.9778327 article EN 2022 7th International Conference on Intelligent Computing and Signal Processing (ICSP) 2022-04-15

Objective To evaluate the clinical value of 125I seeds implantation (RSI) for treatment lymph nodes metastases (LNM) in patients with 131I refractory differentiated thyroid carcinoma (RAIR-DTC). Methods A total 42 RAIR-DTC LNM (14 males, 28 females, median age 49 years) who underwent RSI guided by CT from January 2015 to June 2016 were retrospectively analyzed. All and their serum thyroglobulin (Tg) levels measured 2, 4 6 months post-treatment. The size Tg before after compared,...

10.3760/cma.j.issn.2095-2848.2018.01.003 article EN Zhonghua heyixue yu fenzi yingxiang zazhi 2018-01-25

Reinforcement learning from human feedback (RLHF) has emerged as the primary method for aligning large language models (LLMs) with preferences. The RLHF process typically starts by training a reward model (RM) using preference data. Conventional RMs are trained on pairwise responses to same user request, relative ratings indicating which response humans prefer. RM serves proxy However, due black-box nature of RMs, their outputs lack interpretability, cannot intuitively understand why an...

10.48550/arxiv.2406.12845 preprint EN arXiv (Cornell University) 2024-06-18

Forecasting regional economic activity is a progressively significant element of research. Regional prediction can directly assist local, national, and subnational policymakers. forecast be employed for defining macroeconomic forces, such as stock market cyclicality national labor movement. The recent advances machine learning (ML) models to solve the time series problem. Since parameters involved in ML model considerably influence performance, parameter tuning process also becomes...

10.1155/2022/2900434 article EN Computational Intelligence and Neuroscience 2022-01-30

Abstract Hotspot driver mutations presented by human leukocyte antigens (HLAs) can be recognized antitumor T cells. Based on their advantages of tumor-specificity and immunogenicity, neoantigens derived from hotspot mutations, such as PIK3CA H1047L may serve emerging targets for cancer immunotherapies. NetMHC V4.1 were utilized predicting neoepitopes mutation. Using in vitro stimulation, antigen specific cells targeting the HLA-A*11:01-restricted mutation isolated healthy donor-derived...

10.21203/rs.3.rs-3544061/v1 preprint EN cc-by Research Square (Research Square) 2023-11-09

This research focuses on the direct and indirect systemic risk spillovers among East Asian, European, U.S. stock markets under COVID-19 pandemic. Based GARCH-Copula-CoVaR model, we construct spillover matrix of further explore path through R-vine. The empirical results first show in that Hong Kong exhibited largest change value after pandemic erupted, implying market is more sensitive to extreme events. Compared quiet period, Russia’s output increased significantly pandemic, environment...

10.2139/ssrn.4019499 article EN SSRN Electronic Journal 2022-01-01

Despite tremendous efforts, it is very challenging to generate a robust model assist in the accurate quantification assessment of COVID-19 on chest CT images. Due nature blurred boundaries, supervised segmentation methods usually suffer from annotation biases. To support unbiased lesion localisation and minimise labeling costs, we propose data-driven framework by only image-level labels. The can explicitly separate potential lesions original images, with help generative adversarial network...

10.48550/arxiv.2103.00780 preprint EN cc-by arXiv (Cornell University) 2021-01-01

At present, the prediction of stock market is one most popular and valuable research fields in financial field. More more scholars are engaged forecast, exploring law development, new science technology constantly applied to price forecast. In this paper, we proposed a closing model based on XGBoost Grid SearchCV algorithms. Experimental results show that our idea represents better performance than other machine learning methods. Specifically, RMSE value 1.39%, 2.43% 8.33% lower SVM...

10.1109/csaiee54046.2021.9543136 article EN 2021-08-20

C-HN, TZ and Y-FL conducted the experiments.YY helped in processing medicine

10.17582/journal.pjz/20191106011147 article EN Pakistan Journal of Zoology 2021-01-01
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