A5081412163- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Systemic Lupus Erythematosus Research
- Autoimmune Neurological Disorders and Treatments
- Infectious Diseases and Tuberculosis
- Long-Term Effects of COVID-19
- Infectious Encephalopathies and Encephalitis
- IgG4-Related and Inflammatory Diseases
- SARS-CoV-2 and COVID-19 Research
- Neurological Complications and Syndromes
- Myasthenia Gravis and Thymoma
- Glioma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Brain Metastases and Treatment
- Herpesvirus Infections and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Polyomavirus and related diseases
- Vasculitis and related conditions
- Amyloidosis: Diagnosis, Treatment, Outcomes
- COVID-19 Clinical Research Studies
- Cerebrospinal fluid and hydrocephalus
- Systemic Sclerosis and Related Diseases
- Chronic Lymphocytic Leukemia Research
- Mosquito-borne diseases and control
Brigham and Women's Hospital
2016-2025
Harvard University
2016-2025
Massachusetts General Hospital
2014-2024
Quinnipiac University
2024
Johns Hopkins Medicine
2024
Johns Hopkins University
2024
University of California, San Francisco
2023
Mass General Brigham
2023
The University of Texas Southwestern Medical Center
2022
Hanyang University
2022
To report neuropathological findings and quantify SARS-CoV-2 viral burden for 18 consecutive coronavirus disease 2019 (COVID-19) autopsies.
Neurosarcoidosis poses a diagnostic and management challenge due to its rarity, phenotypic variability, lack of randomized controlled studies guide treatment selection. Recommendations for based on expert opinion are useful in clinical practice provide framework designing prospective studies. In this Delphi survey study, specialists with experience managing patients neurosarcoidosis were invited anonymously complete 2 surveys about key elements evaluation, diagnosis, treatment, monitoring,...
Previous work in animal models has shown that projections from the basolateral amygdala (BLA) progressively infiltrate medial prefrontal cortex (mPFC) birth to adulthood, with most dramatic sprouting occurring during postweanling period. GABAergic (gamma-aminobutyric acidergic) interneurons human homolog of rat mPFC have been implicated pathophysiology schizophrenia, an illness onset is delayed until late adolescence. Here we investigated interaction BLA fibers postnatal day 6 (P6) P120...
Introduction Higher serum urate predicts slower progression in PD. The aim of this work was to assess whether oral inosine alters antioxidant capacity plasma or CSF urinary markers oxidative injury early Methods We assayed and by ferric-reducing power measured DNA oxidation adduct 8-hydroxydeoxyguanosine from urine Safety URate Elevation PD, a randomized, placebo-controlled trial assessing safety elevating <6 mg/dL 6.1–7.0 7.1–8.0 patients with Results At 6 months, 29% higher among mild 43%...
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune condition characterized by unpredictable relapses that affect the optic nerves and spinal cord, which can lead to blindness, paralysis, increased mortality rates. Evidence on clinical economic burden of NMOSD in USA currently lacking.A retrospective, observational cohort study was conducted using data from IQVIA PharMetrics Plus Healthcare Claims Database between January 1, 2012 March 31, 2019. Adults (aged 18 years or more)...
<h3>Background and Objectives</h3> This [<sup>18</sup>F]fluorodeoxyglucose (FDG) PET study evaluates the accuracy of semiquantitative measurement putaminal hypermetabolism in identifying anti–leucine-rich, glioma–inactivated-1 (LGI1) protein autoimmune encephalitis (AE). In addition, extent brain dysmetabolism, their association with clinical outcomes, longitudinal metabolic changes after immunotherapy LGI1-AE are examined. <h3>Methods</h3> FDG-PET scans from 49 age-matched sex-matched...
With some regularity, we have encountered the unusual imaging abnormality of bilateral hippocampal restricted diffusion, either in isolation or combination with other coincident abnormalities. In this retrospective case series, examine clinical and data to explore potential etiologies implications finding. Sixteen cases are presented, including hypoxemia, hypoxemia-ischemia, seizures.