Delineation of glioma extent for surgical or radiotherapy planning is routinely based on MRI. There increasing awareness that contrast enhancement T1-weighted images (T1-CE) may not reflect the entire disease. The amino acid tracer (18)F-DOPA (3,4-dihydroxy-6-[18F] fluoro-l-phenylalanine) has a high tumor-to-background signal and sensitivity imaging. This study compares PET against conventional MRI neurosurgical biopsy targeting, resection planning, target volume delineation.Conventional MR...

Meningioma firmness is a critical factor that influences ease of resection and risk, notably when operating on tumors intimate with neurovascular structures such as the mesial sphenoid wing. This study develops predictive tool using preoperative magnetic resonance imaging (MRI) characteristics to determine meningioma consistency.101 patients intracranial (50 soft/51 firm) were included. MRI 38 (19 soft/19 retrospectively reviewed identify features then correlated intraoperative description...

In the present study, we describe effects of deep tissue massage on systolic, diastolic, and mean arterial blood pressure.The study involved 263 volunteers (12% males 88% females), with an average age 48.5. Overall muscle spasm/muscle strain was described as either moderate or severe for each patient. Baseline pressure heart rate were measured via automatic cuff. Twenty-one (21) different soothing CDs played in background performed over course study. The massages between 45 60 minutes...

The object of this study was to assess outcomes after surgery for recurrent intracranial glioma.The authors retrospectively reviewed cases involving adult patients with glioma undergoing initial (biopsy or resection) and one more additional surgeries at their institution.A total 323 operations were performed in 131 patients. median survival 76 months first surgery, 36 second, 24 third, 26.5 4 surgeries. overall complication rate 12.8% 27.0% second (OR 2.52, p = 0.0068), 22.0% third 1.92, not...

We present a case of an intramedullary melanotic schwannoma (IMS) the thoracic spinal cord. To our knowledge, this is seventh reported IMS central nervous system. Schwannomas are benign nerve sheath tumors neural crest origin composed entirely well differentiated Schwann cells that typically occur in peripheral nerves. Both location and component lesion make it exceedingly rare. will case, theories as to these tumors, clues radiographic identification, current clinical follow-up recommendations.

<b>Objectives</b> We sought to identify if preoperative schwannoma magnetic resonance imaging (MRI) intensities might predict intraoperative consistency. then determined whether consistency correlated with facial nerve outcomes. <b>Design</b> Operative reports from 2000 2010 were searched for tumor description as either <i>soft</i> and/or <i>suckable</i> or <i>firm</i> <i>fibrous</i>. Preoperative T1 and T2 sequences reviewed relative gray matter. Facial function was recorded at the time of...

Background: Opioid‐induced vasodepressor responses have been reported in a variety of species and laboratory models. The aim this study was to ascertain the relative potencies different clinically relevant opioids compared with traditional agents feline pulmonary vascular bed. A second effects morphine identify receptors involved mediation or modulation these effects. Methods: This prospective vehicle‐controlled involving an intact chest preparation adult mongrel cats. various opioids,...

The authors present the case of a 56-year-old right hand-dominant woman who was referred for chronic neck pain and second opinion regarding cervical lesion. patient's localized to subaxial spine in midline. She reported subjective sense intermittent left arm weakness manifesting as difficulty manipulating small objects with her hands fingers. also paresthesias numbness hand. Physical neurological examinations demonstrated no abnormal findings except positive Tinel sign over median nerve at...

In Brief this investigation we sought to identify the role of remifentanil in feline pulmonary vascular bed. Using adult mongrel cats separate experiments, effects glibenclamide (adenosine triphosphate-sensitive K+ channel blocker), diphenhydramine (histamine H1-receptor antagonist), L-N5-(1-Iminoethyl) ornithine hydrochloride (nitric oxide synthase inhibitor), and naloxone (opioid receptor antagonist) were investigated arterial responses agonist), pinacidil activator), bradykinin inducer)....

The objective of this study was to test the hypothesis that fentanyl induces a depressor response in pulmonary vascular bed cat and identify receptors involved mediation or modulation these effects. authors conducted prospective vehicle-controlled at university research laboratory using intact chest preparation adult mongrel cats. In separate experiments, effects diphenhydramine (histamine receptor blocker), glibenclamide (ATP-sensitive K+ channel l-N5-(1-Iminoethyl) ornithine hydrochloride...

Availability of opiate substances through physicians and on the street has led to a rise in dependence addiction resulting countless numbers people hooked these drugs. Long-term use agents results reduction endogenous supply replaced by exogenous compounds. A technique known as Ultrarapid Detoxification (UROD) been developed appears more promising than conventional modalities. UROD modified over 3 decades safe an effective general anesthetic that hemodynamically stable withdrawal without...

Frameless stereotaxy commonly registers preoperative magnetic resonance imaging (MRI) to patients by using surface scalp anatomy or adhesive fiducial markers. Patients' scalps may shift slightly between and final surgical positioning with pinion placement, introducing error. This might be reduced when frameless is performed in a high-field intraoperative MRI (iMRI), as are positioned before imaging. could potentially improve accuracy.To compare stereotactic accuracy iMRI that standard...

Tissue Doppler Imaging (TDI) provides information on systolic function through its mitral annulus velocity wave (Sm), reflecting the peak of shortening myocardial fibers oriented in longitudinal direction. In this study, we evaluated effect load changes Sm. Forty-two cardiac surgical patients with left ventricular ejection fraction >60% were consecutively evaluated. 24 patients, was changed an IV bolus phenylephrine (50-100 microg) or nitroglycerine (300-500 microg); 18 preload a rapid...

Objective: To test the hypothesis that norepinephrine induces a pressor response in pulmonary vascular bed of cat and identify α-(1)adrenoceptor subtypes involved mediation or modulation these effects. Design: Prospective vehicle controlled study. Setting: University research laboratory. Subjects: Intact chest preparation, adult mongrel cats. Interventions: In separate experiments, effects 5-methyl-urapidil, selective α-(1)A-subtype adrenoceptor antagonist, chloroethylclonidine, an...

In accordance with German neurosurgical and neurological consensus recommendations, lead placements for deep brain stimulation (DBS) in patients Parkinson's disease (PD) are usually performed the patient awake "medication off" state. This allows optimal position adjustment according to clinical response intraoperative test stimulation. However, exacerbation of Parkinsonian symptoms after withdrawal dopaminergic medication may endanger by inducing severe "off" state motor phenomena....

A 68-year-old female had a three-week history of severe low back pain radiating down the posterior left buttocks and leg exacerbated by standing walking. Lumbar spine MRI revealed cystic mass with similar intensity to cerebrospinal fluid located on dorsolateral side sacral spinal canal inferior S1 pedicle. There was compression exiting traversing S2 nerve roots. Neurosurgery consult requested evaluate in canal. After clinical evaluation, an unusually synovial cyst thought possible. Cyst...

To test the hypothesis that St. John's wort induces a depressor response in feline pulmonary vascular bed and identify pathways involved mediation or modulation of these effects.Prospective vehicle controlled study.University research laboratory.Intact chest preparation; adult mongrel cats.In separate experiments, effects L-N5-(1-Iminoethyl) ornithine hydrochloride (L-NIO), nitric oxide synthase inhibitor, glibenclamide, an ATP-sensitive K+ channel blocker, meclofenamate, non-selective...