A5015126845- Plant-based Medicinal Research
- Microbial Inactivation Methods
- Berberine and alkaloids research
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Adipose Tissue and Metabolism
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Potato Plant Research
- Optical Coherence Tomography Applications
- Postharvest Quality and Shelf Life Management
- Advanced Fiber Laser Technologies
- Polysaccharides and Plant Cell Walls
- Nutritional Studies and Diet
- Random lasers and scattering media
- FOXO transcription factor regulation
- Synthesis and bioactivity of alkaloids
- Adipokines, Inflammation, and Metabolic Diseases
- Peroxisome Proliferator-Activated Receptors
- Natural Antidiabetic Agents Studies
- Phytochemical Studies and Bioactivities
- Tea Polyphenols and Effects
- Bioactive Natural Diterpenoids Research
- Kruppel-like factors research
- Flavonoids in Medical Research
First Affiliated Hospital of Kunming Medical University
2018-2024
Kunming Medical University
2018-2024
Ningxia University
2024
Beijing Institute of Technology
2007-2023
Zhejiang University of Technology
2021
Ocean University of China
2014-2015
Hefei University of Technology
2013
Quantitative real time RT-PCR has been described as the most sensitive method for detection of low abundance mRNA. To date, no reference genes have screened in half-smooth tongue sole (Cynoglossus semilaevis). The aim this study was to select stable quantitative real-time RT-PCR. Eight housekeeping (18S, TUBA, B2M, ACTB, EF1A, GAPDH, RPL17 and UBCE) were tested at different developmental stages, tissues, following exposure drug SB-431542. Using geNorm, BestKeeper NormFinder software,...
Lycium barbarum (L. barbarum) fruit or extract has been regarded as a superior-grade Chinese medicine, used to modulate body immunity and for anti-aging purposes. However, the underlying molecular mechanisms behind these effects remain unclear. In present study, L. polysaccharides (LBPs), considered major contributor of effects, were elucidate its mechanism action by phenotypic senescence associated-β-galactosidase (SA-β-gal) assays, evaluation survival rates in vivo expression profiling...
The terrifying undiagnosed rate and high prevalence of diabetes have become a public emergency. A efficiency cost-effective early recognition method is urgently needed. We aimed to generate innovative, user-friendly nomograms that can be applied for screening in different ethnic groups China using the non-lab or noninvasive semi-lab data.This multicenter, multi-ethnic, population-based, cross-sectional study was conducted eight sites by enrolling subjects aged 20-70. Sociodemographic...
Chili peppers (Capsicum spp.) exhibit a diverse range of quality characteristics and pectin structures, which are influenced by various factors. This study aimed to investigate the effects ultrasound (US), ultrasonic combined hot blanching (US-BL), freezing thawing (US-FT) on structure vacuum pulsation-dried (VP) chili peppers. The results indicated that US-BL samples exhibited highest L* a* values, retained maximum capsorubin, showed an increase in vitamin C, total phenols, rehydration...
Obesity is defined as the excessive accumulation or abnormal distribution of body fat. According to data from World Atlas 2024, increase in prevalence obesity has become a major worldwide health problem adults well among children and adolescents. Although an increasing number drugs have been approved for treatment recent years, many these inevitable side effects which increased demand new safe, accessible effective prompt interest natural products. Berberine (BBR) its metabolites, known...
Dragon's blood is a bright red resin obtained from Dracaena cochinchinensis. It traditional medicinal that used for wound healing and to stop bleeding. Its main biological activity appears be phenolic compounds found in blood. In this study, the radioprotective effects of were examined after whole brain irradiation rats with either 100 MeV/u Carbon 12C6 heavy ions or 60Co γ-rays. The amounts radiation-induced oxidative stress, inflammatory cytokines apoptosis irradiated rat brains compared...
In this study, we report the cellular uptake studies of novel LX loaded nanoliposomes in H2O2 stress SH-SY5Y Cells synthesized by thin film evaporation method. We have isolated smallest size after 90 min ultrasonification, keeping Polydisperse Index as 0.259. The morphology, size, zepta potential and drug efficiency prepared are characterized using Transmission Electron Microscope (TEM), particle analyzer High Pressure Liquid Chromatography (HPLC). confirmed nanoluposomes measured range...
Abstract The aim of the present study was to explore influence tea consumption on diabetes mellitus in Chinese population. This multi-centre, cross-sectional conducted eight sites from south, east, north, west and middle regions China by enrolling 12 017 subjects aged 20–70 years. Socio-demographic general information collected a standardised questionnaire. A standard procedure used measure anthropometric characteristics obtain blood samples. diagnosis determined using 75-g oral glucose...
There are statistical data indicating that diabetes is a risk factor for Parkinson's disease (PD). Methylglyoxal (MG), biologically reactive byproduct of glucose metabolism, the levels which have been shown to be increase in diabetes, reacts with dopamine form 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ); this formation may provide further insight into connection between PD and diabetes. In study, we investigated role ADTIQ these two diseases determine an aim enhance our...
The present study examined the potential application of Juglans mandshurica Maxim extracts (HT) for cancer therapy by assessing their anti‑proliferative activity, reduction telomerase induction apoptosis and cell cycle arrest in S phase HeLa cells. From perspective using HT as a herbal medicine, photomicroscopy florescent microscopy techniques were utilized to characterize effect on activity morphology. Flow cytometry was employed cells, DNA laddering performed. results showed that inhibited...
The extract of Belamcanda chinensis (L.) leaves (BCLE) is a traditional Chinese herbal medicine for the treatment hyperglycemia in Hainan province, South China. In this study, effects BCLE on obese diabetes were investigated using KK-Ay mice. component F2 alleviate and insulin resistance, as indicated by decreased levels FBG, AUC, GSP, LDH insulin. High hepatic G6Pase PEPCK mice markedly attenuated F2. inhibitory effect GSK-3β enhancement liver glycogen demonstrated that could significantly...
Recent years, image enhancement for single-pixel imaging has developed rapidly and provides an image-free way extracting information. However, the conventional approaches are still based on discontinuously adjustable operations such as integer-order derivatives, which frequently used in edge detection but sensitive to noise. Therefore, how balance between two conflicting demands, i.e. noise suppression, is a new challenge. To address this issue, we introduce arbitrary-order fractional into...
Sinomenine is a morphinan alkaloid with variety of biological activities. Its derivatives have shown significant cytotoxic activity against different cancer cell lines in many studies. In this study, two series sinomenine were designed and synthesized by modifying the active positions C1 C4 on A ring sinomenine. Twenty-three compounds characterized spectroscopy (IR, 1H-NMR, 13C-NMR, HRMS). They further evaluated for their five lines, MCF-7, Hela, HepG2, SW480 A549, normal line, Hek293, using...
To detect the protein and mRNA expression levels of forkhead box C2 (FOXC2) in visceral adipose tissues with type 2 diabetes mellitus (T2DM) as well polymorphism serum FOXC2 gene, to discuss correlations T2DM relevant indices metabolism.A total 18 patients non-diabetic receiving abdominal surgery our hospital were randomly selected. The expressions greater-omental detected by Western blotting RT-PCR. C-512T gene 5' non-translated region was PCR-RFLP. tissues, between glycolipid metabolic...
1) To investigate the effect of FOXC2 on differentiation adipose-derived mesenchymal stem cells. 2) analyze mechanism between expression regulation in adipose and insulin resistance (IR).We first amplified promoter region-512 cloned it into luciferase vector. The reporter gene system was transfected tissue-derived cell to study insulin-mediated expression. We also manipulated protein by either siRNA or overexpression studied capability adipocytes, as well influence several IR-related genes:...
Fractional Fourier transform (FRFT) is the generalization of transform. It provides many significant advantages, such as fractional order new degree freedom and high efficiency great performance for non-stationary signal analysis/processing, that other operations including cannot. Here, we report a hybrid optical system computation arbitrary-order FRFT temporal signals. In experiment, fractional-domain information input signals could be directly acquired by detector. addition, computing...
Gaoreqing freeze-dried powder was effective fraction extracted from Lonicera japonica Thunb.,Scutellaria baicalensis Georgi and Forsythia suspense (Thunb) Vahl. It confirmed to have certain anti-virus, anti-bacterial effects and immuno-enhancing activities. Cell culture influenza viral pneumonia model of mouse were used study its antiviral effect. Plate pathogenic bacteria-infected in established examine Carbon particle clearance test determination serum hemolysin done observe...