A5100342493- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Cancer, Hypoxia, and Metabolism
- Cancer-related gene regulation
- High-Velocity Impact and Material Behavior
- Kruppel-like factors research
- Supercapacitor Materials and Fabrication
- Electrochemical Analysis and Applications
- Immune cells in cancer
- Angiogenesis and VEGF in Cancer
- RNA modifications and cancer
- Glycosylation and Glycoproteins Research
- Ubiquitin and proteasome pathways
- Energetic Materials and Combustion
- Ginseng Biological Effects and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinoids in leukemia and cellular processes
- Advanced Nanomaterials in Catalysis
- Fuel Cells and Related Materials
- Chemokine receptors and signaling
- Electrocatalysts for Energy Conversion
- Ferroptosis and cancer prognosis
Beijing Institute of Technology
2002-2024
Sichuan Normal University
2024
Zhejiang University
2021-2024
Cold Spring Harbor Laboratory
2023
First Affiliated Hospital of Xi'an Jiaotong University
2014-2022
Sun Yat-sen University
2022
Sun Yat-sen University Cancer Center
2022
Shenzhen Second People's Hospital
2022
State Key Laboratory of Chemical Engineering
2007-2021
Dalian University of Technology
2021
Silicon (Si) is a promising material for lithium ion battery (LIB) anodes due to its high specific capacity. To overcome shortcomings such as insulation property and large volume change during the charge–discharge process, novel hybrid system, Si nanoparticles encapsulated in hollow graphitized carbon nanofibers, studied. First, electrospun polyacrylonitrile (PAN)–Si nanofibers were obtained using water collector. The loose nanofiber lumps suspended have inter-fiber distance, allowing situ...
The function of the mammalian brain relies upon specification and spatial positioning diversely specialized cell types. Yet, molecular identities types, their positions within individual anatomical structures, remain incompletely known. To construct a comprehensive atlas types in each structure, we paired high-throughput single-nucleus RNA-seq with Slide-seq, recently developed transcriptomics method near-cellular resolution, across entire mouse brain. Integration these datasets revealed...
Cancer cells prefer to metabolize glucose through aerobic glycolysis, known as the Warburg effect. It plays a crucial role in proliferation and progression of cancer cells. However, complete mechanism remains elusive. In recent studies, signal transducer activator transcription 3 (STAT3) signaling has been discovered have roles cancer‑associated changes metabolism. this study, we find that ginsenoside 20(S)‑Rg3, pharmacologically active component traditional Chinese herb Panax ginseng,...
Characterizing microscale single particles directly is requested for dissecting the performance-limiting factors at electrode scale. In this work, we build a single-particle electrochemical setup and develop physics-based model extracting solid-phase diffusion coefficient (Ds ) exchange current density (i0 from impedance measurements. We find that carbon coating on LiNi1/3 Mn1/3 Co1/3 O2 surface enhances i0 . addition, Ds decay irreversibly by ≈25 % ≈10 %, respectively, when cutoff charge...
The majority of the projectiles used in hypersonic penetration study are solid flat-nosed cylindrical with a diameter less than 20 mm. This aims to fill gap experimental and analytical evolution nose shape larger hollow under penetration. In test, eight ogive-nose AerMet100 steel 40 mm were launched hit concrete targets impact velocities that ranged from 1351 1877 m/s. Severe erosion was observed during high-speed heterogeneous targets, apparent localized mushrooming occurred front recovered...
Dragon's blood is a bright red resin obtained from Dracaena cochinchinensis. It traditional medicinal that used for wound healing and to stop bleeding. Its main biological activity appears be phenolic compounds found in blood. In this study, the radioprotective effects of were examined after whole brain irradiation rats with either 100 MeV/u Carbon 12C6 heavy ions or 60Co γ-rays. The amounts radiation-induced oxidative stress, inflammatory cytokines apoptosis irradiated rat brains compared...
Hypoxia-inducible factor 1 is believed to play a prominent role in the survival and developing progress of cancers. As result, inhibiting α subunit hypoxia-inducible represents an attractive strategy against tumor. Although 1α hypoxia-regulated subunit, increasing evidence indicates that could stable expression under normoxic conditions, regulated by non-hypoxia-mediated mechanisms. However, there are few strategies target conditions. Here, we report ginsenoside 20(S)-Rg3, one main active...
Recently, increasing evidence has indicated that elevation of Hexokinase 2 (HK2) plays an important role in several cancers on regulating cell motility and growth. However, its EMT human ovarian cancer still less to known.The transwell wound-healing assay were used detect the effective HK2 cells. Real Time PCR Western Blotting explore changing EMT-related proteins HK2-modified The clonogenic formation, growth curves MTT assays evaluate proliferation flow cytometry was differences...
Abstract Limited research has been carried out to investigate the local damage features of reinforced concrete (RC) beams under close‐in explosions. To better capture rectangular cross‐sectional RC beams, a numerical study on subjected explosions based calibrated Karagozian & Case (K&C) model was conducted in LSDYNA. First, systematic calibration K&C for performed single‐element analysis. Calibration consists parameter determination new strength surfaces, modification function...
The ionic conductivity of composite solid-state electrolytes (SSEs) can be tuned by introducing inorganic fillers, which the mechanism remains elusive. Herein, ion SSEs is characterized in an unprecedentedly wide frequency range 10-2 -1010 Hz combining chronoamperometry, electrochemical impedance spectrum, and dielectric spectrum. Using this method, it unraveled that how volume fraction v surface fluorine content xF TiO2 fillers tune SSEs. It identified activation energy Ea more important...
A cylinder test was designed for the CL-20-based aluminized explosives to study influence of aluminum (Al) powder properties on explosives' metal driving performance in direction perpendicular detonation wave propagation. The research results showed that: propagation, as Al particle size became larger (in range 2–43 μm), grew stronger; explosive containing 25% much less capable accelerating than formulation 15% Al. Considering two-dimensional flow characteristics products radial and axial...
Abstract Promoting interfacial kinetics of high‐nickel LiNi 0.8 Mn 0.1 Co O 2 (NMC811) is a critical strategy for enhancing rate capability lithium‐ion batteries (LIBs). At the solid‐liquid interface positive electrode, charge transfer across cathode‐electrolyte interphase (CEI) responsible redox reaction, which dominated by desolvation process Li + and NMC811 CEI evolution. Since these two processes are significantly impacted solvation effect electrolytes, herein single‐particle Raman...
In this work, we present a strategy to improve the gas-sensing performance of NiFe2O4 via controllable annealing Ni/Fe precursor fluffy nanosheet flowers. X-ray diffraction (XRD), scanning electron microscope (SEM), nitrogen adsorption–desorption measurements and photoelectron spectroscopy (XPS) were used characterize crystal structure, morphology, specific surface area structure. The was tested results demonstrate that response strongly influenced by resultant flowers with heating rate 8 °C...
The relationship between interface structure (e. g., the facet of solid phase and configuration solvation) reactivity corresponding electrode is a critical issue in electrochemistry. Compared to macroscopic measurements, electrochemical methods established on single-particle scale have advantages establishing structure-property relationship. In recent years, great achievements been made energy storage electrocatalysis that allow evolution kinetics electrodes be understood by employing...
Summary The objective of this study was to the effect load details successive explosions on blast behaviors reinforced concrete (RC) beams. First, loading two identical discussed by considering influences standoff distance, charge mass failure states, and structural responses (displacement support reaction force). And keeping total TNT 1 kg unchanged, numbers investigated 0.5 successively a single RC beams, respectively. Besides, different also considered investigating effects sequences...
A quasi-isentropic study on the process of driving a cylinder with aluminized explosives was carried out to examine influence aluminum (Al) reaction rate expansion and physical parameters detonation products. Based proposed hypothesis relevant isentropic theories, characteristic lines were analyzed, model established. This includes variation wall velocity products Al degree. Using previously reported experimental results, verified be applicative accurate. used calculate for experiments...