James Di Michiel

ORCID: 0000-0001-8243-1012
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About
Contact & Profiles
Research Areas
  • Tracheal and airway disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Long-Term Effects of COVID-19
  • Restless Legs Syndrome Research
  • Trauma Management and Diagnosis
  • Dysphagia Assessment and Management
  • Organ Transplantation Techniques and Outcomes
  • Cystic Fibrosis Research Advances
  • Obstructive Sleep Apnea Research
  • Cardiac Structural Anomalies and Repair
  • Emergency and Acute Care Studies
  • Renal Transplantation Outcomes and Treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Cardiovascular Issues in Pregnancy
  • Pneumonia and Respiratory Infections
  • Injury Epidemiology and Prevention
  • Respiratory Support and Mechanisms
  • Vascular Anomalies and Treatments
  • Vascular Malformations and Hemangiomas
  • Transplantation: Methods and Outcomes
  • COVID-19 Clinical Research Studies
  • Thermal Regulation in Medicine

Concord Repatriation General Hospital
2019-2024

Woolcock Institute of Medical Research
2023

St Vincent's Hospital Sydney
2021

The University of Sydney
2013-2016

Royal Prince Alfred Hospital
2013-2016

Restless legs syndrome (RLS) is a common sensorimotor disorder causing significant distress and commonly seen in the primary care setting.This article outlines epidemiology, pathophysiology, diagnosis management of RLS, with focus on setting.RLS clinical diagnosis, although mimics exist. Brain iron deficiency, dopaminergic dysfunction genetics underpin poorly understood pathophysiology this condition. After repleting stores, reviewing any exacerbating medications attending to...

10.31128/ajgp-02-23-6722 article EN cc-by Australian Journal of General Practice 2023-09-01

Background Mucociliary clearance (MCC) is critical to lung health and impaired in many diseases. The path of MCC may have an important impact on but has never been rigorously studied. objective this study assess the three-dimensional human tracheal disease health. Methods Tracheal was imaged 12 ex-smokers, 3 non-smokers (1 opportunistically during acute influenza repeated after recovery) 5 individuals with primary ciliary dyskinesia (PCD). Radiolabelled macroaggregated albumin droplets were...

10.1136/thorax-2023-221052 article EN Thorax 2024-02-20

Abstract Reduced carbon monoxide diffusing capacity (DL CO ) is common after recovery from severe COVID‐19 pneumonitis. The extent to which this relates alveolar membrane dysfunction as opposed vascular injury uncertain. Simultaneous measurement of nitric oxide NO and DL can partition gas diffusion into its two components: alveolar–capillary conductance (D mCO capillary blood volume (V C ). We sought evaluate D V in the early later periods COVID‐19. Patients attended for post‐COVID‐19...

10.14814/phy2.15660 article EN cc-by Physiological Reports 2023-04-01

Liver disease develops in one‐third of patients with cystic fibrosis ( CF ). It is rare for liver to have its onset after 20 years age. Lung disease, however, usually more severe adulthood. A retrospective analysis was performed on nine patients. Three required lung transplantation approximately a decade transplant, and another underwent combined transplants. Four additional transplants are awaiting assessment One patient With increased survival , several may require than single organ...

10.1111/imj.13126 article EN Internal Medicine Journal 2016-07-01

Despite a population of 600,000 people from 900 islands, there is little published data on the prevalence lung disease in Solomon Islands. We sought to 1) estimate obstructive (OLD) Gizo, Islands, 2) identify risk factors for respiratory this and 3) review current management practices through an audit local emergency department (ED) presentations.

10.2147/copd.s331734 article EN cc-by-nc International Journal of COPD 2021-11-01

Management of recurrent haemoptysis poses a difficult clinical scenario. TISSEEL (Baxter Healthcare Corporation Deerfield, IL, USA) is fibrin sealant often used in surgery to aid control bleeding. However, when endoscopic independently, migration, dislodgement, or even expectoration the clot common complication that may lead recurrence haemoptysis. Here we describe two patients with context malignancy who underwent bronchoscopy, during which they were managed application topical bleeding...

10.1002/rcr2.406 article EN cc-by Respirology Case Reports 2019-01-31

Reduced carbon monoxide diffusion capacity (DLCO) is common after recovery from severe COVID-19. The extent to which this relates membrane dysfunction Vs vascular injury uncertain. Concurrent measurement of nitric oxide (DLNO) and DLCO can partition gas into its two components, conductance (DmCO) capillary blood volume (V<sub>C</sub>). We sought evaluate DmCO V<sub>C</sub> in the early later periods <b>Methods:</b> Patients attended for post-COVID-19 clinical review lung function testing...

10.1183/13993003.congress-2023.pa1170 article EN 01.05 - Clinical respiratory physiology, exercise and functional imaging 2023-09-09

<b>Introduction:</b> The aetiology of central sleep apnea (CSA) remains incompletely understood. While proposed mechanisms exist for those with secondary causes, a complete understanding primary CSA lacking. Here we describe the characteristics patients in our centre and CSA, possible role arousal threshold. <b>Methods:</b> A retrospective study was conducted across undergoing full overnight diagnostic polysomnography (PSG) at Concord Repatriation General Hospital (CRGH) Sydney, Australia...

10.1183/23120541.sleepandbreathing-2019.p24 article EN 2019-04-11
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