A5090562362- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pulmonary Hypertension Research and Treatments
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Long-Term Effects of COVID-19
- Systemic Sclerosis and Related Diseases
- Occupational exposure and asthma
- Heart Rate Variability and Autonomic Control
- High Altitude and Hypoxia
- Occupational and environmental lung diseases
- Pharmaceutical Practices and Patient Outcomes
- Sarcoidosis and Beryllium Toxicity Research
- Nursing Roles and Practices
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Heart Failure Treatment and Management
- Inflammatory Myopathies and Dermatomyositis
- Respiratory and Cough-Related Research
- Myasthenia Gravis and Thymoma
- Thermal Regulation in Medicine
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- Inhalation and Respiratory Drug Delivery
- Injury Epidemiology and Prevention
Concord Repatriation General Hospital
2000-2025
Macquarie University
2024
Isabela State University
2023
Royal Prince Alfred Hospital
2021
Concord Hospital
2014
Repatriation General Hospital
2002
There is a major need for effective, well-tolerated treatments idiopathic pulmonary fibrosis (IPF).To assess the efficacy and safety of autotaxin inhibitor ziritaxestat in patients with IPF.The 2 identically designed, phase 3, randomized clinical trials, ISABELA 1 2, were conducted Africa, Asia-Pacific region, Europe, Latin America, Middle East, North America (26 countries). A total 1306 IPF (525 at 106 sites 781 121 2). Enrollment began November 2018 both trials follow-up was completed...
Abstract Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease (ILD) relating to specific occupational, environmental or medication exposures. Disease behaviour influenced by the nature of exposure and host response, with varying degrees inflammation fibrosis seen within individuals. The differentiation HP from other ILDs important due distinct causes, pathophysiology, prognosis management implications. This Thoracic Society Australia New Zealand (TSANZ) position...
Objective Patients with pulmonary arterial hypertension (PAH) are often recommended supplemental oxygen for altitude travel due to the possible deleterious effects of hypoxia on haemodynamics and right heart function. This includes commercial aircraft travel; however, direct potential risks unknown. Methods Doppler echocardiography gas exchange measures were investigated in group 1 patients PAH healthy at rest breathing room air while 15.1% oxygen, 20 min during mild exertion. Results The 14...
Abstract Reduced carbon monoxide diffusing capacity (DL CO ) is common after recovery from severe COVID‐19 pneumonitis. The extent to which this relates alveolar membrane dysfunction as opposed vascular injury uncertain. Simultaneous measurement of nitric oxide NO and DL can partition gas diffusion into its two components: alveolar–capillary conductance (D mCO capillary blood volume (V C ). We sought evaluate D V in the early later periods COVID‐19. Patients attended for post‐COVID‐19...
Asthma management plans and asthma education have been incorporated into recent guidelines, implementation of these reduces morbidity. Junior doctors are frequently involved in management, but teaching about medical school is seldom assessed. We studied knowledge, confidence practical the effectiveness an interactive workshop final year students. Thirty-five students attended workshop, with 26 returning questionnaires on both two sessions.Students a hour comprising sessions acute stable...
Lung function testing remains a cornerstone in the assessment and management of interstitial lung disease (ILD) patients. The clinical implications Global Initiative (GLI) reference equations updated interpretation strategies remain uncertain.
Reduced carbon monoxide diffusion capacity (DLCO) is common after recovery from severe COVID-19. The extent to which this relates membrane dysfunction Vs vascular injury uncertain. Concurrent measurement of nitric oxide (DLNO) and DLCO can partition gas into its two components, conductance (DmCO) capillary blood volume (V<sub>C</sub>). We sought evaluate DmCO V<sub>C</sub> in the early later periods <b>Methods:</b> Patients attended for post-COVID-19 clinical review lung function testing...