A5100755765- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Lung Cancer Treatments and Mutations
- Diverse Approaches in Healthcare and Education Studies
- Congenital Diaphragmatic Hernia Studies
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Pluripotent Stem Cells Research
- RNA modifications and cancer
- Shoulder Injury and Treatment
- Education, Safety, and Science Studies
- Global Cancer Incidence and Screening
- Diverse Topics in Contemporary Research
- Knee injuries and reconstruction techniques
- Head and Neck Cancer Studies
- Trauma Management and Diagnosis
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Thyroid Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Medical Imaging Techniques and Applications
- Mycobacterium research and diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Antimicrobial Peptides and Activities
Yonsei University
2020-2025
Korea National University of Transportation
2023-2025
Bio-Medical Science (South Korea)
2023-2025
Chungbuk National University Hospital
2014-2024
Asan Medical Center
2023-2024
Ulsan College
2023-2024
Konkuk University
2023-2024
Inje University Busan Paik Hospital
2024
University of Ulsan
2023-2024
The University of Texas Southwestern Medical Center
2022-2024
Human embryonic stem cell (hESC)-derived midbrain dopaminergic (mDA) transplantation is a promising therapeutic strategy for Parkinson's disease (PD). Here, we present the derivation of high-purity mDA progenitors from clinical-grade hESCs on large scale under rigorous good manufacturing practice (GMP) conditions. We also assessed toxicity, biodistribution, and tumorigenicity these cells in immunodeficient rats laboratory (GLP)-compliant facilities. Various doses were transplanted into...
Outcomes of antibiotic treatment for lung disease caused by nontuberculous mycobacteria (NTM) are unsatisfactory. The role adjunctive surgery in the NTM is still unclear.We conducted a retrospective review 70 patients who underwent pulmonary resection from March 2007 to February 2013. All received recommended before and after surgery.A total 74 operations. median age was 50 years. Of patients, 45 (64%) had Mycobacterium avium complex infection (24 M. intracellulare 21 avium) 23 (33%)...
Abstract Hemophilia A (HA) is caused by mutations in coagulation factor VIII ( FVIII ). Genome editing conjunction with patient-derived induced pluripotent stem cells (iPSCs) a promising cell therapy strategy, as it replaces dysfunctional proteins resulting from genetic normal proteins. However, the low expression level and short half-life of still remain significant limiting factors efficacy these approaches HA. Here, we constructed functionally enhanced variant, F309S/E1984V-mutated B...
This study aims to establish the impact of environmental, social, and governance (ESG) activities undertaken by South Korean professional sports clubs on fan trust loyalty. Furthermore, it examines moderating influence citizenship among these connections. Data were gathered via surveys administered 348 spectators at matches two in Korea that are noted for their active ESG activities. Structural equation modeling (SEM) moderation analysis using Jamovi software (version 2.4.8) employed analyze...
Objective To compare thyroid cancer incidence rates and trends between Korean, non‐Korean Asian, non‐Hispanic White populations in the United States, US Korean population South population. Method Population‐based analysis of data. Cases diagnosed during 1999–2014 from Central Cancer Registry (KCCR) Surveillance, Epidemiology, End Results (SEER) 9 detailed Asian/Pacific Islander subgroup dataset were included. Incidence obtained datasets, annual percent change (APC) was calculated using...
Parameters of positron emission tomography-computed tomography (PET-CT) were compared with the results histopathologic examination in order to determine which can provide an objective indication response after neoadjuvant chemoradiation for treatment thoracic esophageal squamous cell carcinoma (SCC).Between August 2003 and January 2010, data on 25 patients who underwent subsequent resection SCC retrospectively reviewed. Changes maximum standardized uptake value (ΔSUVmax), metabolic tumor...
The aims of the study were to investigate psychological distress in pneumothorax patients.A cohort was performed 101 patients with spontaneous pneumothorax. They divided into three groups: (A) under 19 years old, (B) those an intermediate age, and (C) over 45 old. General well-being [Psychological Wellbeing Index-Short Form (PWI-SF)], traumatic event [Impact Event Scale (IES)], resilience [Life Orientation Test-Revised (LOT-R)] assessed.There 35 Group A, 51 B, 15 C. mean length hospital stay...
This study aims to evaluate the incidence and characteristics of chyle leakage after curative oncologic esophagectomy, effectiveness thoracic duct ligation.This is a retrospective cohort using medical records 1514 patients who underwent esophagectomy for esophageal cancer between September 1994 December 2010. Patients whose pleural fluid analysis corresponded were included, drainage patterns by different management groups examined with multilevel models. The during time before ligation also...
Mediastinal paragangliomas are very rare neuroendocrine tumors. Complete resection is the standard treatment of a paraganglioma because tumor's potential malignancy and poor response to chemo- or radiotherapy. However, highly vascular nature tumor its characteristic anatomic location make complete difficult. We report case an anterior mediastinal paraganglioma, which was incidentally found on chest computed tomography scan for chronic cough work-up 55-year-old woman. accomplished using...
Lung cancer is a fatal disease, highlighting the importance of research on related topics, including surgery for lung cancer. However, systematic analyzing national scale limited. This study aimed to investigate using nationwide data in South Korea and analyze trends surgery, its clinical implications. Published articles from Korean National Health Insurance database were used. Although incidence mortality have been improving, it predicted be most common type 2021. The number surgical...
We investigated the prognostic value of International Association for Study Lung Cancer (IASLC)/American Thoracic Society (ATS)/European Respiratory (ERS) classification and assessed relationship between pathologic invasiveness tumor disappearance rate (TDR) in lung adenocarcinoma with ground-glass opacity (GGO).We reviewed data from 202 consecutive patients operated on 2000 2009 clinical T1-2N0 GGO reclassified their histologic subtypes according to IASLC/ATS/ERS classification. Thirty-nine...
Artificial intelligence (AI) techniques can be a solution for delayed or misdiagnosed pneumothorax. This study developed, deep-learning-based AI model to estimate the pneumothorax amount on chest radiograph and applied it treatment algorithm developed by experienced thoracic surgeons. U-net performed semantic segmentation classification of non-pneumothorax areas. The was measured using computed tomography (volume ratio, gold standard) radiographs (area true label) calculated predicted...
Histologic change is a resistant mechanism in lung cancer. The most common histological the switch from adenocarcinoma (AdenoCa) to small cell carcinoma (SCC) against tyrosine kinase inhibitors (TKI). However, it not clear whether other treatment modalities are involved histologic changes.We investigated changes eight cases, after various treatments, and compared molecular profiles between primary tumors changed using exome sequencing where tissue was available.Three cases of AdenoCa that...
<b>Introduction</b> There have been many reports of N1 node metastasis on computed tomography (CT) scan, but not positron emission (PET)-CT in nonsmall cell lung cancer. The aim this study was to analyze the clinicopathologic correlation and survival disease preoperative PET-CT. <b>Methods</b> From January 2003 December 2007, 1,748 curative resections were performed at a single institute. We enrolled 91 patients with clinical All had undergone pulmonary resection mediastinal lymph...
Our study aimed to report the annual changes in lung cancer statistics and analyze trends sociodemographic, medical, financial factors from 2003 2013 national database Korean National Health Insurance (KNHI).Among 7,489 patients with code C34 KNHI database, only newly diagnosed after were included population, for a total of 4,582 patients. Descriptive used characterize treatment patterns medical costs according sociodemographic factors.Approximately 70% subjects male, mean age was 67 years....
Acute aortic dissection (AAD) during pregnancy can be fatal to both the pregnant mother and baby, particularly in patients with Marfan syndrome. We report a case of modified Bentall procedure surgery for AAD 31-year-old woman at 24 weeks gestation The patient recovered well after operation, but unfortunately, fetus could not saved.